Vaxcyte is a biotechnology company focused on developing novel vaccines to address infectious diseases.

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: Working closely with the General Counsel and reporting to the Executive Director, Associate General Counsel, the Director, Senior Counsel will enjoy a high-visibility and high-impact role supporting cross-functional teams. The emphasis of this role will be on drafting, negotiating, executing, and managing contracts with company vendors as well as industry partners, government agencies, and CROs. Additionally, there will be exposure to other legal areas such as compliance. Essential Functions: Prepare and negotiate a wide variety of agreements, including commercial, consulting, vendor, supply, master service, licensing, collaboration and development, joint venture, sponsored research, CRO, manufacturing, confidentiality, and other agreements essential to Vaxcyte’s business. Provide counsel to, and participate in strategy discussions with, internal stakeholders to ensure the Company’s contracts meet strategic objectives while mitigating corporate risk. Lead the continuous improvement of law department operations through problem solving, strategic planning, project management, process, and systems improvement (include contracts management systems), and financial/budget management, including through the implementation of new software tools. Define contracting processes and systems and provide necessary reports and project status information to management and other appropriate staff. Oversee outside counsel engagements, manage department budget, and implement cost‑containment and efficiency initiatives. Advise internal clients regarding legal issues, including identifying, managing, and communicating risks and opportunities in commercial transactions. Support continuous improvements of forms, policies and processes to help streamline and simplify deals and product/service terms. Develop and maintain strong working relationships with internal and external business partners as well as other members of the legal team. Requirements:&nbsp; Juris Doctor degree with exceptional academic credentials. Must hold and maintain an active law license in a jurisdiction that permits the attorney to lawfully provide the required legal services, in accordance with all applicable laws, regulations, and rules of court. Minimum 6-10+ years of legal experience drafting, structuring, and negotiating agreements, including commercial, consulting, vendor, supply, master service, licensing, collaboration and development, joint venture, sponsored research, CRO, manufacturing, confidentiality, and other agreements essential to Vaxcyte’s business. Other combinations of education and/or experience may be considered. In-house legal experience at a biotechnology, pharmaceutical, or biopharmaceutical company is a plus. Experience managing contracts processes and policies and using contracts lifecycle management (CLM) tools (e.g., Ironclad). Hands‑on experience implementing and administering CLM systems and legal‑tech tools including AI applications; aptitude for leveraging data analytics to drive decisions. Experience handling commercial contract disputes and dispute resolution. Experience driving cost-saving initiatives. Experience using AI tools such as Spellbook and ChatGPT Enterprise. Excellent analytical skills; creative, pragmatic problem-solving abilities in a transactional context; and efficient, precise drafting of customized agreements. Excellent analytical, communication and organizational skills, and demonstrated ability to effectively collaborate and manage several simultaneous projects under deadline pressure. Experience working on FDA regulatory and quality assurance matters is preferred. Reports to: Executive Director, Associate General Counsel &nbsp; Location: Hybrid/Open to remote with the ability to work West Coast hours &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Salary Range: $236,000 - $270,000 (SF Bay Area). Salary ranges for non-California locations may vary.We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Director, Senior Counsel

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: Vaxcyte is seeking a highly skilled, energetic and experienced candidate to join our Information Technology (IT) organization as Senior Manager, IT Master Data Management (MDM). This critical role involves active participation in the implementation of our SAP Enterprise Resource Planning (ERP) System. This role is key in defining and managing master data and associated processes within and beyond the ERP ecosystem, helping to implement requisite management and reporting/analytics tools, and establishing a comprehensive data governance framework. The ideal candidate will bring deep master data management expertise within the biotech industry, experience in building master data governance, and designing data solutions for the reporting and analytics inclusive of master data elements. This role must have strong analytical skills and the ability to collaborate cross-functionally to drive strategic and operational insight and excellence.&nbsp; Essential Functions: SAP Master Data Management Actively participate in the SAP S/4HANA project. Responsible to identify and ensure precise and efficient integration of master data as ERP MDM Lead. Oversee creation, maintenance, and governance of master data across SAP modules (e.g., Materials, Vendors, Customers, GL Accounts, Departments). Collaborate with business units to define data standards, naming conventions, and data quality rules. Take lead to ensure data quality and resolve issues related to master data. Help establish and co-lead (with Supply Chain) a Data Governance Council to uphold data integrity and best practices. Define and manage master data management processes to align with business objectives. Develop and implement strategies to improve data accuracy and consistency across ERP and related functions. Design and implement data validation and cleansing routines. Work closely with technical teams to architect and build reporting/analytical solutions inclusive of master data elements. Monitor and report on data management performance and identify continued areas for improvement. Maintain compliance with industry regulations and standards related to data management. &nbsp; Data Analytics and Reporting Develop and maintain scalable data pipelines and integrations into enterprise data lakes. Build and support dashboards, visualizations, and KPIs using tools like Power BI, Tableau, or SAP Analytics Cloud. Collaborate with business stakeholders to gather reporting requirements and translate them into technical solutions. Utilize advanced data analysis to support business insights, forecasting, and strategic initiatives. Ensure data security, privacy, and compliance in all analytics work. &nbsp; Requirements:&nbsp; B.S. / B.A. degree in Business Administration, Information Systems, Data Science, or a related field. Advanced degree or relevant certifications preferred. 8+ years of experience supporting ERP initiatives within Life Science industries. Deep understanding of SAP ERP systems (S/4HANA) and master data structures. Experienced in SAP Master Data Management and respective tools. Hands-on experience with data integration fundamentals and designing analytical solutions (i.e., data lakes, analytical reports, dashboards, etc.). Proven experience with analytics tools including SAP Analytics Cloud, Azure, Tableau. Proficiency in data visualization and dashboarding tools (e.g., Power BI, Tableau, SAP Analytics Cloud). Strong SQL skills; experience with Python or R is a plus. Strong analytical and problem-solving abilities. Ability to analyze complex data and make data-driven decisions. Solid knowledge of ERP processes and data areas including Finance, Procurement, Inventory, HR. Excellent verbal and written communication skills. Ability to effectively communicate with stakeholders at all levels of the organization. Demonstrated leadership and team management skills. Ability to lead and motivate cross functional teams to achieve high levels of performance. Strong organizational skills with the ability to manage multiple activities simultaneously and meet deadlines. High level of accuracy and attention to detail in all aspects of work. Strong interpersonal skills with the ability to build and maintain effective relationships with internal and external stakeholders. Ability to thrive in a fast-paced, dynamic environment and adapt to changing priorities and requirements. Reports to:&nbsp;Senior Director, IT Enterprise Systems &nbsp; Location:&nbsp;San Carlos, CA &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Salary Range: $182,000 - $212,000 (SF Bay Area). Salary ranges for non-California locations may vary. &nbsp;We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Senior Manager, IT Master Data Management

Director, Environmental, Health, & Safety (EH&S)

Senior Manufacturing Systems Analyst

Senior Associate Scientist, Upstream Polysaccharide Process Development

Sr. Regulatory Document Formatting Specialist

Clinical Data Manager

Associate Director, Clinical Quality Assurance

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making. Summary: Vaxcyte is seeking a highly skilled and experienced candidate to join our Commercial Manufacturing and Supply Chain (CSMC) organization. This critical role entails active participation in the implementation of SAP Enterprise Resource Planning System and OMP Advanced Planning System, building master data capabilities, processes and tools and team from the ground up.&nbsp; The role excels at collaborating across various supply chain functions and establish a comprehensive data governance framework, process, tools, and team. The ideal candidate brings deep master data management expertise within the biotech industry, experience in building master data governance, processes and a strong team from the ground up, strong analytical skills, and the ability to collaborate cross-functionally to drive strategic and operational excellence.&nbsp; Essential Functions: Oversee the management of master data for supply chain, manufacturing, logistics, direct procurement, and quality functions. Define and manage the data management process to align with business objectives. Establish and lead a Data Governance Council to uphold data integrity and best practices. Actively participate in the SAP and OMP APS implementation projects, responsible to ensure precise and efficient integration of master data. In the mid-to-long term, build and lead a team responsible for master data management in SAP and OMP Advanced Planning System. Develop and implement strategies to improve data accuracy and consistency across the supply chain. Collaborate with cross-functional teams to ensure data quality and resolve issues related to master data. Monitor and report on data management performance, identifying areas for improvement. Maintain compliance with industry regulations and standards related to data management. Requirements:&nbsp; B.S. / B.A. degree or advanced degree (preferred) Minimum 10 years of supply chain experience within the biotechnology or pharmaceutical industries&nbsp; Has completed multiple SAP S/4 HANA lifecycle implementations in master data roles Proven track record successfully building and growing master data management programs and teams Proficient in SAP ERP Master Data Management, GMP data standards, and respective tools&nbsp; Strong analytical and problem-solving abilities. Capable of analyzing complex data and making data-driven decisions In-depth understanding of supply chain processes, including manufacturing, logistics, procurement, and quality Excellent verbal and written communication skills. Ability to effectively communicate with stakeholders at all levels of the organization Demonstrated leadership and team management skills. Ability to lead and motivate cross-functional teams to achieve high levels of performance Strong organizational skills with the ability to manage multiple activities simultaneously and meet deadlines High level of accuracy and attention to detail in all aspects of work Strong interpersonal skills with the ability to build and maintain effective relationships with internal and external stakeholders Ability to thrive in a fast-paced, dynamic environment and adapt to changing priorities and requirements Reports to: Senior Director, Supply Planning, Inventory Management and Systems &nbsp; Location: San Carlos, CA &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Salary Range: $174,000 - $202,000 (SF Bay Area). Salary ranges for non-California locations may vary. &nbsp; Relocation:&nbsp; This role is eligible for relocation assistance.We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Associate Director, Supply Chain Master Data Management

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: We are seeking a highly skilled and experienced Senior Director, Supply Chain, ERP Transformation, to join our dynamic team. As we transition from a clinical-stage organization to a fully integrated commercial biotech company, we are building the foundational capabilities essential to reliably deliver our first commercial vaccine to patients. The Senior Director, Supply Chain ERP Transformation role will play a pivotal leadership role in designing and implementing the end-to-end processes required to support this transformation. This is a business role and not a technology role. In this role, you will lead a team of process leaders in developing and executing Plan-to-Deliver capabilities—including planning, scheduling, production, quality release, and logistics—as well as overseeing the comprehensive Direct Procure-to-Pay process, including purchasing, receiving and inventory management, quality release, and reconciliation. The ideal candidate is well-versed in industry standards and best practices that are scalable, compliant, and aligned with our future-state operating model. You bring deep supply chain expertise, proven cross-functional leadership, and a strong track record of driving transformation through effective business process and technology alignment. If you are passionate about building leading-class supply chain capabilities and enabling organizational transformation in a fast-paced, innovative environment, we invite you to apply and make a meaningful impact on the future of healthcare. Essential Functions: Serve as the Global Business Process Owner: Own and champion the end-to-end Plan-to-Deliver and Direct Procure-to-Pay value streams with Business Process Leaders, ensuring processes are integrated, optimized, and aligned with organizational objectives. Lead Process Design and Standardization: Drive the development and implementation of robust, scalable, and compliant supply chain processes that will support Vaxcyte’s transition to a commercial-stage operation. Strive to balance agility, efficiency, and compliance while standardizing workflows. Act as a Change Leader: Inspire and guide stakeholders through transformational change, fostering a performance-driven culture and embracing new ways of working to unlock organizational potential. Integrate Business Process and Technology: As a core member of the SAP Project PMO, ensure business processes and ERP capabilities are harmoniously integrated to deliver the intended target-state business outcomes and sustain long-term value. Drive Cross-Functional Collaboration: Build and nurture strong partnerships across Supply Chain, Manufacturing, Quality, Regulatory, Procurement, Finance, IT, and Commercial functions. Facilitate alignment and collaboration across both clinical and commercial supply chain operations. Establish Data Governance Strategy: Define and execute a comprehensive data governance framework to enable to the Plan to Deliver and Direct Procure to Pay Business Processes, ensuring data integrity and accuracy, reliability, and operational efficiency. Develop and Implement Metrics and KPIs: Design, deploy, key performance indicators to monitor and assess process effectiveness, identify improvement opportunities, and drive a culture of continuous improvement. Oversee SOP and Documentation Development: Lead the creation and maintenance of standard operating procedures and business process documentation to support operational readiness and ensure compliance with Health Authority inspection requirements. Lead and Mentor Cross-Functional Teams: Manage, inspire, and develop a high-performing team of business professionals, cultivating an environment of continuous learning, growth, and operational excellence. Collaborate with Executives and Senior Leaders to ensure strategic alignment between ERP, operational initiatives, and corporate objectives, providing critical insights and recommendations to inform decision-making and drive enterprise-wide results. Requirements:&nbsp; Bachelor's degree in supply chain management, business administration, or a related field. A master's degree or professional certification (e.g., APICS, CSCP) is preferred. 12+ years of experience in supply chain, manufacturing, procurement, quality functions, preferably within the biotechnology industry. Proven track record of success in a senior management role. Has held Business Process Owner/Lead roles previously with significant experience designing biotech business processes Proficiency in SAP ERP is required and OMP Advanced Planning Systems is preferred. Has completed multiple full life-cycle SAP S/4 HANA implementations Strong analytical and problem-solving abilities. Ability to analyze complex data and make data-driven decisions. Exceptional verbal and written communication skills. Ability to effectively communicate with stakeholders at all levels of the organization. Demonstrated leadership and team management skills. Ability to inspire and motivate a team to achieve high levels of performance. Strong project management skills with the ability to manage large complex projects and meet deadlines. High level of accuracy and attention to detail in all aspects of work. Ability to thrive in a fast-paced, dynamic environment and adapt to changing priorities and requirements. Strong interpersonal skills with the ability to build and maintain effective relationships with internal and external stakeholders. Reports to: Senior Director, Supply Planning, Inventory Management and Systems &nbsp; Location: San Carlos, CA &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Salary Range: $211,000 - $246,000 (SF Bay Area). Salary ranges for non-California locations may vary. &nbsp; Relocation:&nbsp; This role is eligible for relocation assistance.&nbsp;We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Director, Supply Chain, ERP Transformation

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: Vaxcyte is looking for an energetic and talented individual to join Vaxcyte’s Facilities organization. The primary function of this Director-level position is to lead Facilities operations and site services for Vaxcyte’s Headquarters and to develop and maintain global security programs and policies. This position will manage and grow a high-performing and service-centric team comprised of full-time employees, contingent workers and 3rd party partners. Beyond functional and technical experience, the primary keys to success for this role focuses on relationships, culture, trust, forward thought, and operational excellence. This position reports to the Senior Director Facilities and will work out of Vaxcyte’s San Carlos office. &nbsp; Note: rotational, shared 24x7 on-call support is required of this role. Essential Functions: Partner closely with the Director of Lab Operations to establish, monitor and maintain the labs and all lab equipment. Support planning oversight for the installation of lab equipment. Help cultivate a culture of compliance with job-appropriate policies, procedures and training. Collaborate, develop and evolve a rolling 3-5 year strategic Facilities roadmap for Vaxcyte’s HQ and associated spaces. Develop and maintain oversight of Vaxcyte’s global security program.&nbsp; This will include the development of access controls, oversight of Security for Vaxcyte’s HQ in San Carlos, develop visitor/vendor management protocols and practices and any governance documents/polices required under a global security envelop. Plan and co-lead relocations, expansions and redesign initiatives. Oversee ongoing space planning and assignment move/add/change efforts. Manage site functions as assigned. Establish and maintain 24x7 on-call schedule, site lead roster and emergency call tree for Facilities team. Help drive key processes and systems related to Facility operations to ensure they are integrated and monitored. Develop building and equipment standards, including Basis of Design for labs and office spaces to support future growth and development Implement and maintain an Integrated Workplace Management System (IWMS). Maintain master calendar for required inspections, preventative maintenance, submissions, renewals, and (re)certifications via Facilities Computerized Maintenance Management System (CMMS).&nbsp; CMMS will be the master database for the general facilities including the Labs and lab equipment. Establish and operationalize strategic relationships with key external partners. Lead, coach and manage a high-performing Facilities team with a focus on career growth. Help nurture and grow workplace engagement through creative Facilities solutions. Liaise regularly with property managers, external agencies and key 3rd party partners. Engage regularly with employees and business partners to forge relationships and build trust. Operationalize and/or automate Facilities functions for improved consistency and efficiency. Support the development of procedures that comply with appropriate cGxP and other statutory requirements. Manage Vaxcyte HQ Facilities projects and serve as SME for cross-functional and enterprise initiatives. Establish functional KPI’s and report regularly on performance against metric/measure targets. Create a customer-centric Facilities support capability built upon solid process and technology. Work with IT and business partners to identify, implement and evolve Facilities systems. Partner closely with Finance to establish, monitor and maintain Facilities budgets. Plan, oversee and track Facilities-related procurement; help optimize procurement process. Serve as Facilities SME and point of contact during audits. Assist with Vaxcyte’s emergency and continuity planning with ongoing table-top exercises. Support troubleshooting and perform minor repairs in office and laboratory settings. Member of Emergency Response Team. Requirements:&nbsp; BS in Engineering or similar technical-related degree, with 12 years Facilities experience in the life sciences industry, biotech preferred. 5+ years’ people-management experience required. Other combinations of education and/or experience may be considered. Project management experience with office and lab builds; manufacturing a plus. Expert-level proficiency with facilities and lab systems such as BMS, CMMS, ELN/LIMS. Proficient, hands-on experience with biotech facility and laboratory instruments and equipment. Relentless focus and passion around process improvements (efficiency and automation). Fluent in Facilities-related statutory/regulatory requirements for a public life sciences company. Proficiency developing and managing corporate EH&amp;S programs. Compete training and maintain training qualifications for ERT Practical experience with system/equipment qualification plans and protocols. Ability to thrive in a highly dynamic and fluid environment where priorities may quickly change. Excellent communication, customer service and relationship skills are an absolute must. Reports to: Senior Director, Facilities &nbsp; Location:&nbsp;San Carlos, CA &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Salary Range: $197,000 - $230,000 (SF Bay Area). Salary ranges for non-California locations may vary.We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Director, Facilities

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: Vaxcyte is seeking an experienced candidate to support implementation of our OMP Advanced Planning (APS), SAP Enterprise Resource Planning (ERP) and future Supply Chain systems, as part of our Commercial Manufacturing and Supply Chain (CMSC) organization.&nbsp; This is a business role, not an IT role.&nbsp; It is focused on process definition, systems design, and integration of the Supply Chain Management, Procurement, Logistics, Manufacturing, AD/QC, and Quality business functions at Vaxcyte.&nbsp; The candidate will work closely with the Director, Supply Chain Systems to implement the Plan to Deliver and Direct Procure to Pay workstreams. Essential Functions: Project Management:&nbsp; Partner with project managers to develop detailed project plans. Coordinate and lead cross functional teams to ensure successful project execution per the project plans.&nbsp; Monitor progress, manage schedule, issues and risks, and provide status updates. APS and ERP Design and Implementation: Support the end-to-end design and implementation of SAP&nbsp; and OMP for the Supply Chain Management, Procurement, Manufacturing, AD/QC and Quality business functions. Develop and align integrated business processes for the above functions, incorporating best practices and industry standards while adhering to compliance standards and regulatory requirements. Stakeholder Management: Serve as the primary Vaxcyte Switzerland contact for the OMP and SAP implementation projects. Communicate effectively with all internal and external stakeholders and project team members including business partners, software vendors, and integrators.&nbsp; Facilitate team meetings to keep stakeholders engaged and informed. Escalate appropriately to senior management for awareness and decision making. Resource Management: Identify resources and skills necessary to complete project activities and meet project goals.&nbsp; Coordinate with department managers to secure necessary resources and support.&nbsp; Monitor resource allocation and develop contingency plans to address resource constraints. Business Training and Support: Develop and deliver training programs to ensure end user adoption of business processes and systems.&nbsp; Develop and maintain training documentation including policies, standard operation procedures (SOPs), and work instructions.&nbsp; Performance Management and Optimization: Work with global process owners and key stakeholders to align key performance indicators (KPIs). Monitor performance, analyze data, and identify areas for optimization. Drive continuous improvement through iterative enhancements. Master Data Management: Support the governance of master data for supply chain systems.&nbsp; Lead the creation, maintenance and quality control of master data.&nbsp; Ensure data is aligned with business needs and meets regulatory requirements.&nbsp; Design and implement the data management end-to-end process and data quality and accuracy KPIs. Process and systems continuous improvement:&nbsp; Lead process and system improvements, enhancements, and upgrades to scale Vaxcyte’s capabilities and integration with our primary Switzerland-based CMO. Secure business resources to support initiatives. Ensure end-user support and troubleshooting are provided post implementation and verify new functionalities are properly rolled out and intended benefits are achieved. SAP and OMP EU Business Systems Owner: Ensure systems are maintained in compliance with changing and/or new regulatory and validation requirements.&nbsp; With IT, maintain validation documentation and ensure the systems operate in a state of control.&nbsp; Work closely with quality assurance to comply with industry standards and regulatory guidelines Requirements:&nbsp; S. / B.A. degree or Advanced Degree (preferred). 8+ years of experience working in commercial pharmaceutical / biotech companies with a focus on APS/ERP implementations Has completed multiple SAP S/4 HANA lifecycle systems implementations in similar roles PMP or similar project management certification and proficient in project management tools (e.g. MS Project and Smartsheet) Strong experience working with CMOs, Software Vendors and Integrators In-depth knowledge of GMPs, FDA regulations and biotech industry standards Strong experience leading cross-functional teams Proficient in change management methodologies (e.g. Prosci ADKAR, Kotter’s Change Model) or demonstrated experience in leading change management initiatives Design and implementation expertise in APS and ERP systems with a proven track record of managing and delivering fast-track projects successfully Comprehensive knowledge of Supply Chain, Procurement, Manufacturing, Quality and Regulatory processes Experience with systems validation processes, including developing and executing validation plans to ensure compliance with regulatory requirements Experience with Lean, Six-Sigma or other process improvement methodologies Strong communication, problem-solving, analytical and decision-making skills Reports to: Director, Supply Chain Europe &nbsp; Location: Switzerland: Visp, VS or Steinhausen, ZG &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Relocation:&nbsp; This role is eligible for relocation assistance.&nbsp; We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Senior Manager, Supply Chain Systems

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: At Vaxcyte, we’re on a mission to protect humankind from the consequences of bacterial diseases through the development of high-fidelity vaccines. As we grow, we are looking for a Talent Acquisition Coordinator to join our collaborative, fast-moving Talent Acquisition team. This is a high-impact, hybrid role for someone who thrives on creating exceptional candidate experiences and has a sharp eye for operational efficiency. You will own critical parts of the interview coordination process, support recruiting projects across departments, and gain exposure to both recruiting and recruiting operations. At the start, this position will be 20-30 hours per week and may flex up to 40 hours a week depending on business needs. If you are passionate about building great teams, have a systems mindset, and love solving problems before they arise, we would love to meet you. Essential Functions: Partner with Recruiters and hiring teams to deliver an exceptional, high-touch candidate experience from first contact through offer. Own interview scheduling (onsite and virtual) for roles across all levels, including executive-level coordination. Manage recruiting calendars, Zoom logistics, and conference room bookings; greet candidates onsite and ensure a welcoming experience. Coordinate candidate travel and process reimbursements. Collaborate with Executive Assistants and Hiring Managers to streamline scheduling and resolve conflicts proactively. Support job posting and description creation across multiple departments. Manage contractor POs and SOWs in IronClad and NetSuite. Maintain the highest level of professionalism, confidentiality, and candidate care. Assist with other projects/assignments as assigned to support Talent Acquisition Operations or other initiatives. Requirements: Bachelor’s degree or equivalent experience. 1-3+ years in an administrative, coordination, or recruiting support role (experience as a Talent Acquisition Coordinator strongly preferred). Experience using Greenhouse or another modern ATS. Excellent communication skills—written, verbal, and interpersonal—with the ability to interact confidently with all levels, including senior executives. High attention to detail, time management, and organizational skills. Problem-solver who stays calm under pressure and can juggle competing priorities. Empathy and a strong customer service mindset—must advocate for a great experience for all stakeholders. A collaborative and growth-oriented mindset. Ability to think in systems and create repeatable, efficient workflows. Reports to: Sr. Recruiter, Talent Acquisition Location: San Carlos, CA; Hybrid (2-3 days/week) Expected Contract Length: 12 months Hourly Range: $37.00- $41.00 &nbsp;We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Talent Acquisition Coordinator (Contract)

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making. Summary: The Associate Director for Global ASAT Polysaccharide (PS) will lead and facilitate the analytical (tech transfer and lifecycle of commercial manufacturing) program prioritization, and execution to drive the successful launch of products. This role provides leadership in validation and &nbsp;implementation of analytical methods to characterize and ensure the quality of polysaccharide for drug substances throughout the lifecycle of commercial manufacturing, with a focus on understanding and controlling critical quality attributes (CQAs) of the polysaccharide, adhering to all relevant regulatory standards and guidelines. Works in alignment with network organization to ensure on-time execution and appropriate planning for commercial lifecycle management and coordinating cross-functional efforts for regulatory filings, facility readiness, and launch supplies. This role also provides leadership to ensure that the organization is equipped to effectively communicate the analytical and scientific rationale for polysaccharides and DSI testing to internal stakeholders, relevant CMOs, and to regulatory agencies. The incumbent will work with the organization to ensure on-time execution and appropriate planning for analytical readiness and lifecycle management for commercial manufacturing. Reporting to the Senior Director for Global ASAT, the Director will collaborate on overall program strategy, with primary responsibility and accountability for the analytical leadership for commercial drug substance (DSI and DS) functions across the network. Essential Functions: The ASAT group will focus on qualifying/validating, and optimizing analytical methods/technologies used in the commercial manufacturing process and through its life cycle. The ASAT Associate Director for PS will support the commercial analytical control strategy (release and characterization) including establishing the analytical methods for DSI and DS. The ASAT PS will support commercial operations as well as quality control (QC) on all aspects of analytical methodology and heightened characterization studies for polysaccharide. &nbsp; PS Commercialization - Provide technical and scientific advice for internal and external stakeholders in support of the successful execution of launch plans and post-launch commercial activities. Support the analytical control strategy with advanced state-of-the-art analytical equipment and technologies and routine trouble shooting. Life Cycle Management of process and product. Analytical validation and comparability - Validate new analytical techniques and methods. Provide leadership for analytical validation and comparability activities. Effectively communicate the scientific and commercial rationale of analytical aspects to the Manufacturing organization for commercialization. Analytical Characterization - Provide analytical support activities related to method qualification/validation, product characterization, and comparability assessment for multiple programs. Tech Transfer - Provide technical support for complex analytical challenges. Tech-transfer new technologies - support technical transfers and integration of new technologies. Lead Tech Transfer Support (including comparability protocols and reports). Support Technical Teams - Support of our internal and external manufacturing network, including materials management and data analytics. Review/Author method validation protocols, reports, and transfer activities. Review analytical documents including but not limited to protocols, reports, and procedures. Regulatory - Engage in support of reviewing and authoring of regulatory filings and responding to questions received from health authorities. Effectively communicate the scientific and commercial rationale for analytical to the Boards of Health for regulatory submissions for commercialization. Contribute to CMC analytical aspects of regulatory filings; review and assemble information for analytical sections in regulatory submission documents (e.g. IND, IMPD, NDA, etc). Support World-Wide Post Approval Submissions. Analytical thought partner - Serve as a thought partner with Regulatory, CMC, Quality, Supply Chain, Sourcing, and Process Engineering colleagues. Interface - Collaboration with cross-functional teams across the internal and external network to drive the successful development and commercial launch of pipeline products. Work in a team environment to manage third-party vendors including analytical method implementation, qualification/validation, and transfer for drug substance and drug product projects. Communicate - Connect and build strong working relationships with others, demonstrating strong emotional intelligence and an ability to communicate clearly and persuasively. Leadership - Contribute as Global ASAT lead and as a member of the Global Manufacturing Operations, with an aim to ensure effective and efficient delivery of our life-enhancing therapies to our patients. Act as the CMC team analytical lead member in cross functional developmental teams. Leadership - As a member of the Global ASAT organization, lead matrixed teams focused on analytical lifecycle of test methods for commercialization with an aim to ensure effective and efficient delivery of our life-enhancing therapies to our patients. Travel - 10-30% of travel required. Requirements:&nbsp; Degree(s) in Chemical or Biochemical Engineering, Chemistry, Biochemistry, or related discipline with a minimum of 9+ years of relevant experience for Ph.D., 11+ years for M.S./M.A., or 14+ years for B.S./B.A. Other combinations of education and/or experience may be considered. Extensive experience in analytical method development, validation, method transfer, commercial launch, and/or analytical lifecycle management of polysaccharides and/or glycoconjugate vaccines preferred. Demonstrated ability to coordinate CDMO activities and direct experience with directing outsourced assay validation, stability, and quality control in support of CMC activities. Leadership experience in analytical development, QC, ASAT or MSAT in supervisory and/or matrixed team roles. Able to leverage deep technical knowledge in a collaborative manner to establish strategic plans and achieve collective goals. Excellent organization, problem solving, and strategic planning skills. Highly skilled in both verbal and written communication with the ability to interact effectively with people of diverse backgrounds and perspectives. Proactively recognizes needs and potential challenges and directs activities to implement effective solutions. The ability to seek and analyze data from a variety of sources to support decisions and to align others with the organization's overall strategy. An entrepreneurial and creative approach to developing new, innovative ideas that will stretch the organization and push the boundaries within the industry. Reports to: Senior Director, Global Analytical Sciences and Technology (ASAT) Lead &nbsp; Location: San Carlos, CA; Open to remote &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Salary Range: $173,000 - $201,000 *(SF Bay Area). Salary ranges for non-California locations may vary.We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Associate Director, Global Analytical Sciences and Technology (ASAT) Polysaccharide

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: As we grow, we are seeking a strategic and collaborative Associate Director of Data and Knowledge Management to ensure the integrity, accessibility, and effective use of data and knowledge assets across the organization. The Associate Director of Data and Knowledge Management will lead enterprise-wide efforts to structure, govern, and utilize data and knowledge resources critical to our process development, clinical, regulatory, and operational activities. This role is instrumental in ensuring scientific data integrity, regulatory readiness, and the preservation of institutional knowledge in a dynamic, fast-paced clinical environment. Essential Functions: Data Management, Strategy &amp; Governance: Acquire and gather data from manufacturing nodes throughout the supply chain to enable regulatory filings, process monitoring, and continuous improvement. Develop and oversee data management strategies to support operations, development, and regulatory submissions. Own data verification for all commercial regulatory submissions. Lead the integration of structured and unstructured data across departments (e.g., preclinical, clinical, regulatory, CMC). Knowledge Management: Build systems and workflows to capture and retain organizational knowledge, including protocols, study results, lessons learned, and decision rationales. Develop tools and processes that enable scientific teams to find, share, and reuse knowledge efficiently. Champion a knowledge-sharing culture across scientific and operational functions. Collaboration &amp; Leadership: Partner with regulatory, quality, R&amp;D, IT and contract manufacturing teams to understand data and knowledge needs and align solutions. Lead cross-functional initiatives focused on digital transformation, data harmonization, and collaboration tools. Manage and mentor a team of data professionals, analysts, and knowledge specialists. Analytics &amp; Insights: Ensure timely access to high-quality data for operational decision-making. Partner with data science team to drive data visualization, reporting, and insights. Support the use of AI/ML and automation for improved data analysis and knowledge extraction. Compliance &amp; Risk Management: Ensure compliance with data protection and clinical trial regulations, including GDPR, HIPAA, and 21 CFR Part 11. Identify and mitigate risks related to data security, access, and retention Requirements:&nbsp; Bachelor’s, Master’s or PhD degree in Life Sciences, Data Science, Information Management, or related field. Minimum of 9+ years of relevant experience for Ph.D., 11+ years for M.S./M.A., or 14+ years for B.S./B.A.&nbsp; 8+ years of experience in data and/or knowledge management, with minimum 3 years in a life sciences or biotech setting. Proven experience leading enterprise data governance and knowledge sharing initiatives in a highly regulated environment. Strong project management and communication skills; able to work cross-functionally with scientific and operational teams. Experience with tools like SharePoint, Veeva Vault, Confluence, Tableau, and SQL is highly desirable. Experience supporting clinical trials and regulatory submissions (e.g., IND, BLA) strongly preferred. Background in immunology, vaccines, or infectious disease R&amp;D is highly preferred. Experience in scaling systems and processes in a high-growth, early- to mid-stage biotech company is preferred. Reports to: Sr. Director, Process Validation &nbsp; Location: San Carlos, CA &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Salary Range: $208,000 – $243,000 (SF Bay Area). Salary ranges for non-California locations may vary. &nbsp; Relocation:&nbsp; This role is not eligible for any relocation assistance.&nbsp;We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Associate Director of Data and Knowledge Management

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making. Summary: As we grow, we are seeking a strategic and collaborative&nbsp;Associate Director, Regulatory Support for Global ASAT (Analytical Sciences and Technology)&nbsp;to manage and support all activities associated with the analytical aspects of regulatory CMC related support. The Associate Director, Regulatory Support will manage the timelines and deliverables to ensure submission requests are aligned with project milestones, and ensure that all the sections are complete, well-written, and meet all relevant requirements. This role is instrumental in ensuring scientific data integrity, regulatory readiness, and the preservation of institutional knowledge in a dynamic, fast-paced clinical environment. Essential Functions: Plan and prepare analytical sections for global regulatory CMC-related content pertaining to Marketing Application (new and renewals), Post-approval Variations, and periodic reports for North America and International markets in accordance with the developed regulatory strategy. Collaborate and align with Reg CMC Product Lead regarding change record assessments of proposed analytical changes and regulatory strategy, provide regulatory guidance for support of implementation to cross-functional stakeholders. Ensure required analytical regulatory documents for submissions are complete, accurate, and meet relevant requirements. Manage the timelines and deliverables to ensure analytical submissions are aligned with program milestones and assure that regulatory query timelines are met. Proactively identify issues and escalate to Global Analytical and Reg CMC Product Lead. Develop relationships with Analytical Development, QC, Regulatory Affairs, Technical Development, Sites (internal and external), and Quality to support submission preparation. Process documentation requests for ASAT to support key application activities and queries. Assist with data/documentation gathering for regulatory authority (FDA, Health Canada) interactions for assigned projects such as pre-Agency meeting requests, briefing packages. Managing and/or assisting in responding to country health authority queries. Work in Regulatory and Quality databases via Veeva platform. Requirements:&nbsp; Degree(s) in Life Sciences, Data Science, Information Management, or related discipline with a minimum of 9+ years of relevant experience for Ph.D., 11+ years for M.S./M.A., or 14+ years for B.S./B.A. Other combinations of education and/or experience may be considered. Proven experience leading enterprise data governance and knowledge sharing initiatives in a highly regulated environment. Strong project management and communication skills; able to work cross-functionally with scientific and operational teams. Experience with tools like LIMS, SharePoint, Veeva Vault, Confluence, Tableau, and SQL is highly desirable. Experience supporting clinical trials and regulatory submissions (e.g., IND, BLA) preferred. Background in immunology, vaccines, or infectious disease R&amp;D preferred. Experience in scaling systems and processes in a high-growth, early- to mid-stage biotech company preferred. Reports to: Senior Director, Global Analytical Sciences and Technology (ASAT) Lead &nbsp; Location: San Carlos, CA; Open to remote &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Salary Range: $173,000 - $201,000 (SF Bay Area). Salary ranges for non-California locations may vary.We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Associate Director, Regulatory Support for Global ASAT

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: We are seeking an experienced Data Systems Engineer to lead the design, implementation, and support of Laboratory data management systems at Vaxcyte. The ideal candidate will have a strong background in deploying lab data systems used in the Biotech industry, coordinating cross-functional teams, and ensuring compliance with relevant industry standards. This role is essential in enhancing laboratory workflows, ensuring data integrity, and improving operational efficiency across scientific domains. Essential Functions: Act as the Systems Lead and Administrator for Vaxcyte’s Benchling ELN to manage user accounts, permissions, and system configurations in alignment with organizational needs. Lead implementation of data system business process mapping and requirements gathering. Create detailed lifecycle documentation for Benchling and other lab data systems. Troubleshoot and resolve technical issues in collaboration with IT and end users. Oversee cross-functional projects, ensuring lab data systems are integrated seamlessly with existing IT systems and aligned with business needs. Provide technical support and training, ensuring optimal end-user experience. Partner with scientists to assess pain points and design improvements in Benchling workflows, schemas, and templates to optimize system performance. Implement new features and modules to support evolving operational processes while maintaining technical documentation. Contribute to data governance by establishing best practices. Maintain vendor relationship to stay updated on product developments, raise ongoing technical challenges, and influence product roadmap priorities. Requirements:&nbsp; Bachelor's degree in Computer Science, Information Systems, or Engineering with a minimum of 5 years of hands-on experience configuring and administering Laboratory Information Management Systems (LIMS), Electronic Lab Notebooks (ELN) or similar Other combinations of education and/or experience may be considered. Hands on experience with Benchling configuration, administration, and/or integrations. Experience gathering user requirements and translating them into technical deliverables. Proficiency in master data management and workflow optimization within lab data. Excellent communication, interpersonal, and training skills, with experience in leading end-user training and support. Ability to translate technical concepts for non-technical end users. Knowledge of data structures and relational database Knowledge of SQL and experience with data interfaces and integrations within lab data. Knowledge of programming languages such as Python. Previous experience in Biotech, pharma, or life science research environment. Familiarity with laboratory workflows: R&amp;D and CMC. Reports to:&nbsp;Data Systems Manager, LIMS &amp; ELN &nbsp; Location:&nbsp;San Carlos, CA &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Salary Range: $138,000 - $161,000 (SF Bay Area). Salary ranges for non-California locations may vary. &nbsp;We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Data Systems Engineer

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: The Director of IT SAP Systems is a key leadership role responsible for the successful planning, delivery and ongoing management of Vaxcyte’s SAP and Advanced Planning &amp; Scheduling (APS) initiatives. This individual will oversee and manage the implementation of our upcoming SAP Enterprise Resource Planning (ERP) and OMP Advanced Planning Systems (APS). This position requires a strategic thinker with a high level of expertise in SAP and APS systems. They will provide team leadership to ensure that business goals and objectives are met efficiently and effectively. This is a collaborative hands-on role working closely with business partners and subject matter experts from supply chain, finance and other business teams to deliver ERP/APS solutions that will support our growth through vaccine commercialization and beyond. The position reports to the Sr Director of Enterprise IT Systems at Vaxcyte’s San Carlos, California headquarters. Essential Functions: Lead and execute SAP and OMP implementations and subsequent projects ensuring alignment with organizational objectives and strategic goals. Deep experience collaborating with stakeholders to understand their requirements, manage expectations, and provide regular project updates. Vendor collaboration, budget planning, preparing for and facilitating steering committee meetings. Identify, assess, and mitigate project risks to minimize potential impact on project outcomes. Implement change management processes for SAP and APS to ensure smooth transitions and adoption of new systems and processes. In addition, develop support for tracking GxP and SOX related changes. Monitor project performance using appropriate systems, tools, and techniques, and implement corrective actions as needed. Create and curate program standards including tools, deliverables and document management. Promote a culture of continuous improvement by identifying areas for enhancement and implementing best practices in SAP and APS through initial implementation and lifecycle management. Lead a cross functional team from the business, IT, consultants, contract manufacturer resources, and other professionals to achieve high performance and project success. Requirements:&nbsp; Bachelor’s degree in Information Technology, Business Administration, or a related field. A master’s degree or relevant certifications (e.g., PMP, SAP certification) is desired. At least 12 years of experience in program/project management, with multiple SAP and APS system implementations. Other combinations of education and/or experience may be considered. Experience leading large and complex initiatives, including development of detailed timelines, milestone creation, and resource requirements to ensure timeline execution and delivery. In-depth knowledge of SAP systems, including SAP S/4HANA and integration techniques. Experience implementing APS systems (OMP experience is desired). Experience delivering large scale SAP projects. Expertise with agile methodology, global deployments and data migration planning. Leadership: Strong leadership and team management skills, with the ability to motivate and guide cross-functional teams. Excellent verbal and written communication skills, with the ability to effectively communicate complex technical concepts to non-technical stakeholders. Strong background implementing and maintaining GxP validated and SOX regulated systems Strong analytical and problem-solving skills, with the ability to identify issues and implement effective solutions. Experience in identifying and managing project risks, with a proactive approach to mitigation. Proficiency in change management principles and techniques to facilitate smooth transitions and adoption of new systems. Experience with biotech/pharma companies both pre and post commercialization. Reports to:&nbsp;Senior Director, Enterprise IT Systems &nbsp; Location: San Carlos, CA &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Salary Range: $226,000 - $264,000 (SF Bay Area). Salary ranges for non-California locations may vary. &nbsp; Relocation:&nbsp; This role is eligible for relocation assistance.&nbsp;We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Director, IT SAP Systems

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: The Director, IT Supply Chain Systems is a key leadership role responsible for the successful delivery and management of Vaxcyte’s Supply Chain systems projects and programs. This individual will support the Supply Chain team with the implementation of our SAP ERP system and our OMP Advanced Planning System (APS). This position requires expertise in SAP and APS systems, and project management. This role will be a hands-on technical role and will provide team management and leadership for IT Supply Chain systems and ensure that business goals and objectives are met efficiently and effectively. This is a collaborative role working closely with the Supply Chain team to deliver a system that will support Vaxcyte’s growth through commercialization. Essential Functions: Lead, mentor, develop and manage the IT supply chain systems team, fostering a culture of collaboration, accountability and continuous improvement. Develop and manage the IT supply chain systems roadmap and budget, ensuring resources are allocated effectively and efficiently. Program Management: Provide IT leadership for supply chain portions of SAP implementation ensuring alignment with organizational objectives and strategic goals. Plan and lead IT OMP implementations and subsequent upgrades and enhancements. Program Planning and Execution: Develop detailed project plans, including timelines, milestones, and resource allocation, and ensure timely execution and delivery of supply chain systems. Performance Monitoring: Monitor system and project performance using appropriate systems, tools, and techniques, and implement corrective actions as needed. Continuous Improvement: Promote a culture of continuous improvement by identifying areas for enhancement and implementing best practices in SAP and APS program management. Requirements:&nbsp; Bachelor’s degree in Information Technology, Business Administration, or a related field. A master’s degree or relevant certifications (e.g., SAP certification) is desired. A minimum of 12 years’ experience supporting supply chain systems, with multiple SAP and APS system implementations. Other combinations of education and/or experience may be considered. Stakeholder Engagement: Extensive experience collaborating with stakeholders to understand their requirements, manage expectations, and provide regular project updates. Extensive knowledge of supply chain, procurement, manufacturing and quality systems and regulatory processes. Plan to deliver E2E Process experience including demand and supply planning, CMO scheduling and manufacturing, logistics, direct procurement, and quality release. In-depth knowledge of SAP systems, including SAP S/4HANA and integration techniques. Deep experience implementing APS systems (OMP experience strongly desired). Project Management: Proven experience in managing supply chain projects, including planning, execution, and delivery. Expertise with system integrations with internal and external systems Strong leadership and team management skills, with the ability to motivate and guide cross-functional teams. Communication: Excellent verbal and written communication skills, with the ability to effectively communicate complex technical concepts to non-technical stakeholders and to communicate with internal business partners and external parties (e.g. contract manufacturers) Problem-Solving: Strong analytical and problem-solving skills, with the ability to identify issues and implement effective solutions. Experience managing GxP validation systems and the processes required to manage and maintain validation. Experience with biotech/pharma companies both pre and post commercialization. International travel may be required up to 15%. Reports to:&nbsp;Senior Director, Enterprise IT Systems &nbsp; Location:&nbsp;San Carlos &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Salary Range: $225,000 - $263,000 (SF Bay Area). Salary ranges for non-California locations may vary. &nbsp; Relocation:&nbsp; This role is eligible for relocation assistance.&nbsp;We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Director, IT Supply Chain Systems

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.At Vaxcyte, we are always looking for bright, committed, and innovative people who are passionate about making a difference. &nbsp; If you do not see an opportunity on our Careers Page that is a good match with your background, please submit your resume to be part of our Talent Community to be considered for future opportunities. &nbsp; We also encourage you to regularly visit our Careers Page as we continue to grow and add more opportunities.We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

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Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: We are seeking a highly skilled Manager, Quality Systems to ensure adherence to regulatory standards, continuous improvement, and operational excellence within our organization. The ideal candidate will have experience in quality management systems (QMS), a background in regulatory requirements, and experience successfully validating, implementing, and maintaining quality systems in a regulated industry. Essential Functions: Assist with development and maintenance of the company's Quality Management System (QMS) in accordance with company procedures and regulatory requirements (e.g., 21CFR Part 11). Assist with driving continuous improvement initiatives that relate to QMS to enhance quality, efficiency, and compliance across all departments. Collaborate cross-functionally with IT, and other departments to ensure alignment of quality objectives and initiatives. Strive to foster a culture of quality and continuous improvement. Assist with preparation for and participate in regulatory inspections and customer audits, ensuring readiness and compliance. Ensure alignment with department management and company vision. Promote a quality mindset and quality excellence approach to all activities. Complete other responsibilities, as appropriate. Requirements:&nbsp; Bachelor's degree in a relevant scientific discipline. Minimum of 5 years of experience in quality management within a regulated industry (e.g., medical devices, pharmaceuticals, biotechnology). Demonstrate knowledge of GXP regulations and guidelines as it pertains to Quality Systems. Experience in assisting with the validation, implementation, and managing Quality Management Systems (QMS) compliant with FDA regulations (e.g., 21 CFR Part 820), and other relevant regulatory requirements. Experience driving cross-functional collaboration. Excellent analytical and problem-solving abilities, with a keen attention to detail. Experience with Veeva QMS required. Knowledge or experience with Computer System Validation and/or Computer Software Assurance highly desirable. Experience with test script execution, a plus. Ability to work in a collaborative team environment. Reports to: Associate Director, Quality Systems &nbsp; Location: Hybrid; San Carlos, CA &nbsp; Expected Contract Length: 6-7 months &nbsp; Hourly Range: $70.00 - $78.00 &nbsp;We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Manager, Quality Systems (contract)

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.&nbsp; Summary: Vaxcyte is looking for a talented Document Specialist, who will be responsible for managing manufacturing documents in a GXP compliant environment. This includes, but is not limited to, batch records, specifications, and memos. The role is focused on maintaining documentation in the Quality Systems associated with the manufacturing and testing of our vaccines and preparing for future clinical trials. Essential Functions: Maintenance of the Quality Systems documentation in Veeva (electronic document control system) and other electronic systems where required. Perform document specialist functions in QA, including managing the lifecycle of GMP documents in Veeva, including creation, revision, approval, distribution and archival, ensuring compliance with internal procedures and regulatory standards. Work closely with quality assurance, external vendors, functional areas and Project Management team for daily management of routing, revisions, approval, and filing of documents within defined timelines. Organize and ensure accurate and reliable filing systems for all electronic and paper-based GMP documents. Support audits as appropriate (internal and regulatory). Requirements:&nbsp; Bachelor’s BA/BS degree or equivalent experience and minimum of 2 years of biopharmaceutical industry experience. Other combinations of education and/or experience may be considered. Experience with managing key Quality Management System processes (e.g., Document Control, Change Management, Training). 2+ years of experience with document management utilizing EDMS systems, Experience with Veeva QualityDocs preferred. Familiarity with documents and records associated with GxP manufacturing and testing activities. Understanding of current regulatory expectations including 21CFR Part 11 requirements. Demonstrated ability to collaborate and influence across organization to gain support and commitment for team goals; effective management of groups of professionals to achieve desired results. Strong professional interpersonal and communications skills, both verbal and written, to provide clear direction for the business, vendors, and internal stakeholders. Strong attention to detail, organizational skills, ability to work in a faced paced environment. Ability to meet deadlines and multi-task efficiently. Working knowledge with SmartSheet, Microsoft Office Suite, Word, Excel, PowerPoint, Visio, and Adobe. Reports to: Senior QA Document Specialist &nbsp; Location: San Carlos, CA; Hybrid &nbsp; Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component. &nbsp; Salary Range: $89,000 – $103,000 (SF Bay Area). Salary ranges for non-California locations may vary.We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

QA Document Specialist II

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: The Development organization is comprised of four Process teams: Protein, Polysaccharide, Conjugate Drug Substance (Conjugation), and Drug Product. These Process Development teams are supported by Analytical Development and Formulation Development teams. Vaxcyte is looking for a Senior Associate Scientist (contract) with experience in microbial fermentation and upstream processing to join the Upstream Polysaccharide Process Development team. The candidate will be responsible for collaboration on experimental design and execution of experiments to further develop and optimize upstream processes for polysaccharide manufacturing using microorganisms. The successful candidate will have practical laboratory experience related to microbial fermentation processes and eager to utilize and learn new laboratory skills. The role will require &gt;50% time in the lab and this person will be able to independently detail experimental procedures/results in written and presentation formats. The successful candidate may interface closely with the cross-functional team, write detailed technical reports, present experimental results internally, and may potentially interface with external CMO partners. Essential Functions: Support in study design, execute, and analyze experiments for upstream polysaccharide for bacterial fermentation (BSL2) and vaccine production processes. Execute experiments to develop the upstream process parameters (e.g., media, feed, pH, temperature, dissolved oxygen, agitation, etc.) and to enhance product yield, quality, and consistency. Perform microbiology related work including plating, colony selection, Gram staining and cell enumeration on microscope. Perform fermentation vessel assembly and script writing for process automation and execute fermentation experiment in shake-flask and lab scale bioreactors. Prepare media and buffer as needed for experiments. Operate and maintain instrumentation for bacterial fermentation and primary recovery (centrifugation, filtration, etc.) of bacterial polysaccharides utilizing aseptic techniques. Support analytical method execution including optical density, residual metabolites and polysaccharide concentration and other relevant analytical techniques. Assist in executing late-stage process development studies including process characterization. Keep accurate and current records of research and/or project related activities in laboratory notebooks and Electronic Lab Notebook. Prepare and review protocol, technical reports, SOPs, and batch records. Present and communicate scientific data and results to internal stakeholders. Be an outstanding teammate and collaborate effectively with downstream, analytical, and manufacturing teams within Polysaccharide Development and Manufacturing team to ensure seamless technology transfer and process integration. Requirements:&nbsp; MSc in Chemical/Biochemical Engineering, Biotechnology, or similar degree with a minimum of 3 years of relevant industry experience, or BSc with a minimum of 5 years of relevant industry experience. Experience in handling microorganisms with proper aseptic techniques to perform upstream processing related work in flasks/bioreactors. Hands-on experience and theoretical understanding of key processing operations such as microbial culture, fermentation process, microbial media, and process optimization and relevant analytical technologies; experience with depth filtration, continuous centrifugation is a plus. Develop and optimize scripts for instrumentation, including Ambr® systems, to enhance efficiency and automate processes, leveraging programming languages such as Python or R is a plus. Experience with Design of Experiments (DoE) principles and DoE software. Process characterization experience is a plus. Cell banking expertise, colony selection and genetic analysis of recombinant strains is a plus. Proficiency with computer programs such as Microsoft Excel, Word, PowerPoint, Visio and JMP. Working knowledge of GMP requirements. Proven ability to succeed in a cross-functional team environment, effectively managing multiple projects and contributing to team outcomes. Strong interpersonal skills, with excellent written and verbal communication abilities. Reports to: Sr. Scientist, Upstream Polysaccharide Process Development &nbsp; Location: San Carlos, CA &nbsp; Expected Contract Length: 12months &nbsp; Hourly Range: $54/hr. - $60/hr. &nbsp; &nbsp;We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Senior Associate Scientist (contract), Upstream Polysaccharide Process Development

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: As Vaxcyte’s products progress towards late stage and commercialization, we are looking for people with experience in Quality Control for late stage or commercial products to strengthen our global Quality Control team. Within that Quality Control Organization, we are seeking a Senior Manager Quality Control acting as single point of contact for our CDMO in Europe. The Senior Manager QC will represent the executive function of QC ensuring analytical strategies are implemented at our CDMO and/or external testing lab to ensure the quality, accuracy, and compliance of testing and analytical services. Working closely with the analytical technical lead and other functions within Analytics, Process Development, Quality Assurance, Operations, and Regulatory functions, this role is accountable that testing and release is performed at our CDMO in a timely and compliant manner to ensure secure and uninterrupted supply of Vaxcyte’s innovative therapies. Essential Functions: Implement the analytical control strategy for our programs at our CDMO/contract labs and ensure they are aligned with the CDMO's goals and objectives as well as comply with relevant regulations and industry standards. Implement, and maintain robust quality control systems that encompass sampling, testing, documentation, and release procedures. Ensure on-time performance for QC testing at our CDMO’s or contract laboratories related to raw materials, intermediates, and drug substance Ensure that contracted QC laboratories are equipped with appropriate instrumentation and equipment, maintained according to regulatory requirements, and calibrated regularly to ensure accuracy and reliability of test results. In partnership with analytical technical lead and analytical science and technology as well as the contract laboratories, oversee method validation and transfer activities between contract laboratories. Assure that appropriate systems for data management, including secure storage, retrieval, and retention of QC data and documentation are in place. Ensure that all testing activities are well-documented and comply with Good Documentation Practices (GDP). Review and approval of analytical data, test reports, and certificates of analysis (CoAs) generated by contract laboratories to verify accuracy, completeness, and compliance with specifications for both release and stability testing. Support investigations and deviations, out-of-specification (OOS), out-of-trend (OOT), out-of-expectation (OOE) results, laboratory incidents, and customer complaints related to contract laboratory testing, collaborating with contract laboratories and internal stakeholders to implement corrective and preventive actions (CAPAs). Provide technical support for product related inspections by Health Authorities. Writing, review and approval of documents related to Quality Control to ensure compliance with applicable regulatory and industry standards. Requirements:&nbsp; Bachelor of Science with 8+ years of relevant experience in biotechnology/pharmaceutical industry. Experience in Pneumococcal vaccines is a plus. Excellent experience in managing CDMOs and/or contract laboratories. Comprehensive knowledge in cGMP and experience in multi-national regulations. Excellent communication, negotiation, and relationship-building skills, with the ability to collaborate effectively with internal and external stakeholders. Strong analytical and problem-solving abilities, with a focus on data-driven decision-making and continuous improvement. Strong teamwork and interpersonal skills. Relentless focus and passion around process improvements (efficiency and automation). Reports to: Head of Quality Control &nbsp; Location:&nbsp;Visp, Switzerland &nbsp; Compensation: The compensation package will be competitive and includes an equity component. &nbsp; Relocation:&nbsp; This role is not eligible for relocation assistance.&nbsp; We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Senior Manager, Quality Control

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: As Vaxcyte’s products progress towards late stage and commercialization, we are looking for people with experience in Quality Control for late stage or commercial products to strengthen our global Quality Control team. Within that Quality Control Organization, we are seeking a Senior Manager, Quality Control acting as single point of contact for our CDMO in Europe. The Senior Manager QC will represent the executive function of QC ensuring analytical strategies are implemented at our CDMO and/or external testing lab to ensure the quality, accuracy, and compliance of testing and analytical services. Working closely with the analytical technical lead and other functions within Analytics, Process Development, Quality Assurance, Operations, and Regulatory functions, this role is accountable that testing and release is performed at our CDMO in a timely and compliant manner to ensure secure and uninterrupted supply of Vaxcyte’s innovative therapies.&nbsp; Essential Functions: Implement the analytical control strategy for our programs at our CDMO/contract labs and ensure they are aligned with the CDMO's goals and objectives as well as comply with relevant regulations and industry standards. Implement, and maintain robust quality control systems that encompass sampling, testing, documentation, and release procedures. Ensure on-time performance for QC testing at our CDMO’s or contract laboratories related to raw materials, intermediates, and drug substance Ensure that contracted QC laboratories are equipped with appropriate instrumentation and equipment, maintained according to regulatory requirements, and calibrated regularly to ensure accuracy and reliability of test results. In partnership with analytical technical lead and analytical science and technology as well as the contract laboratories, oversee method validation and transfer activities between contract laboratories. Assure that appropriate systems for data management, including secure storage, retrieval, and retention of QC data and documentation are in place. Ensure that all testing activities are well-documented and comply with Good Documentation Practices (GDP). Review and approval of analytical data, test reports, and certificates of analysis (CoAs) generated by contract laboratories to verify accuracy, completeness, and compliance with specifications for both release and stability testing. Support investigations and deviations, out-of-specification (OOS), out-of-trend (OOT), out-of-expectation (OOE) results, laboratory incidents, and customer complaints related to contract laboratory testing, collaborating with contract laboratories and internal stakeholders to implement corrective and preventive actions (CAPAs). Provide technical support for product related inspections by Health Authorities. Writing, review and approval of documents related to Quality Control to ensure compliance with applicable regulatory and industry standards. Requirements:&nbsp; Bachelor of Science with minimum 9 years of relevant experience in biotechnology/pharmaceutical industry. Experience in Pneumococcal vaccines is a plus. Excellent experience in managing CDMOs and/or contract laboratories. Comprehensive knowledge in cGMP and experience in multi-national regulations. Excellent communication, negotiation, and relationship-building skills, with the ability to collaborate effectively with internal and external stakeholders. Strong analytical and problem-solving abilities, with a focus on data-driven decision-making and continuous improvement. Strong teamwork and interpersonal skills Relentless focus and passion around process improvements (efficiency and automation). Reports to: Head of Quality Control&nbsp; &nbsp; Location: Visp, Switzerland&nbsp; &nbsp; Compensation: The compensation package will be competitive and includes an equity component. &nbsp; Relocation:&nbsp; This role is not eligible for relocation assistance.&nbsp;We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.&nbsp; &nbsp; WHAT&nbsp;we do is every bit as important as&nbsp;HOW&nbsp;we do it!&nbsp;Our work together is guided by four enduring core values: &nbsp; *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. &nbsp; *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. &nbsp; *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. &nbsp; *MODEL EXCELLENCE:&nbsp; The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: Vaxcyte is looking for an energetic and talented individual to join Vaxcyte’s Vaccine Product Development organization as a Stability Manager within the Quality Control Unit. The primary function of this level position is to manage the stability program for various projects in preclinical and clinical development.&nbsp; The position will be an integral part of the team implementing and maintaining cGMP Stability for all phases of clinical development. Primary responsibility will include managing stability studies for individual projects and stability data analysis. This individual will collaborate with QC members in a highly collaborative and cross-functional environment. The ideal candidate will apply strong stability experience, ensure compliant operations and documentation, foster open communication, and pursue data-driven approaches. Essential Functions: Designs, coordinate, and execute stability studies for early and late-stage vaccine products according to regulatory guidelines and company protocols. Summarize vaccine stability results by applying analytical testing expertise to ensure scientific and technical excellence. Utilize statistical software like JMP to perform rigorous statistical analyses, ensuring robust interpretation of data and adherence to regulatory standards. This includes, but not limited to, creating, implementing, and managing stability databases, performing data trending and statistical analysis, study and testing forecasting and reporting of metrics, creation, revision and approval of SOP's, stability protocols and reports in accordance with current GMP, FDA, EU, Global and ICH guidelines and regulations. Produce impactful PowerPoint presentations to effectively communicate stability data to diverse project team members. Support the attainment of project milestones by facilitating stability monitoring and determining expiration dates for clinical and in-process materials. Authors, reviews, revises, and approves SOP's, stability protocols and reports, memo’s, regulatory and specification documents (as required). The Stability Manager will also assist with leading the functionality and maintenance of stability related processes and systems. Drives continuous improvement activities for the clinical stability programs. Ensures that the GMP stability program continuously aligns with FDA, ICH and other international agencies. Manages Quality Systems records for QC Stability- creates, assesses, reviews Deviations, Change Controls, CAPA's and other applicable stability-related investigations and events. Guide and work with others to identify opportunities for continuous improvement and implement/maintain solutions. Provide strong teamwork in establishing a quality culture and shared accountability. Ensure GMP compliance is built into the design and implementation of processes and systems, including tracking metrics to monitor and improve performance. Requirements: MS or BS with minimum of 8 years of industry experience in Pharma / Biotech industry required. Other combinations of education and/or experience may be considered. Strong understanding of vaccine stability principles, including degradation pathways, accelerated stability testing, and shelf-life determination. Demonstrated proficiency and expertise in various analytical methodologies, particularly in the context of stability testing and assessment of biologics or vaccines. Solid understanding of relevant FDA, EU, and ICH regulatory guidelines and pharmacopeia as applicable to stability study design, expiry dating, and analytical method qualification/validation for biologics and vaccines. Solid understanding and hands-on experience of applying basic statistical tools for stability data trending and rate analysis to support retest period/ shelf-life proposals. Attention to detail and excellent skills in record keeping / documentation. Experience in IND, NDA and BLA submission is highly preferred. Experience working in a regulated (GLP / GMP) environment. Extensive technical writing experience. Strong interpersonal skills; ability to communicate effectively both verbally and in written formats. Solid understanding of product development activities in biotech/drug/vaccine development, including key interdependencies, and knowledge of proven development strategies and tactics. Ability to work globally with CMOs in different countries and continents. Reports to: Director, Stability Location: San Carlos, CA Compensation: &nbsp;The compensation package will be competitive and includes comprehensive benefits and an equity component. Salary Range: $147,000 – $171,000 *(SF Bay Area). Salary ranges for non-California locations may vary.&nbsp; &nbsp;We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. &nbsp;

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