Scholar Rock Holding is a biopharmaceutical company committed to discovering and developing innovative medicines that target the transforming growth factor beta (TGFβ) superfamily of proteins to treat serious diseases with high unmet medical need.

scholar-rock-holding

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<p><em>Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.</em></p>
<p><em>As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fscholarrock.com%2F&amp;esheet=54602249&amp;newsitemid=20260911564629&amp;lan=en-US&amp;anchor=ScholarRock.com&amp;index=10&amp;md5=af235377a7f0c8fbf451d85159f006ff"><strong>ScholarRock.com</strong></a> and follow @ScholarRock on X and on LinkedIn.</em></p>
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<div><strong style="font-size: 18px;">Summary of Position:</strong></div><div><br></div><div>
<p>Scholar Rock is seeking a strategic, service-oriented, and collaborative Workplace Services Senior Manager to lead workplace strategy and day-to-day workplace operations for our site. This role will shape how space, services, and employee experience support the evolving needs of the business, with responsibility for strategic space planning, workplace utilization, occupancy planning, hospitality, facilities coordination, vendor performance, budgets, and site readiness.</p>
<p>The Workplace Services Senior Manager will lead and partner with business leaders and cross-functional stakeholders, translate workforce and growth plans into practical workplace solutions, and continuously improve the workplace to deliver a safe, flexible, efficient, and polished experience for employees, visitors, and senior leaders. This role is expected to be primarily on-site to maintain visibility, support daily operations, and ensure a high level of service across the workplace. Occasional schedule flexibility may be needed to support key meetings, workplace events, executive visits, or business initiatives.</p>
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Workplace Services Senior Manager

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<p><em>Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.</em></p>
<p><em>As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fscholarrock.com%2F&amp;esheet=54602249&amp;newsitemid=20260911564629&amp;lan=en-US&amp;anchor=ScholarRock.com&amp;index=10&amp;md5=af235377a7f0c8fbf451d85159f006ff"><strong>ScholarRock.com</strong></a> and follow @ScholarRock on X and on LinkedIn.</em></p>
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<div><strong style="font-size: 18px;">Summary of Position:</strong></div><div><br></div><div>
<p>The Senior Manager, Lab Operations will provide leadership and oversight for Scholar Rock’s laboratory operations and support services. This role is responsible for maintaining safe, reliable, and efficient laboratory environments and for ensuring that equipment, facilities, systems, vendors, and operational resources effectively support research activities.</p>
<p>The ideal candidate is a collaborative and service-oriented leader with biotechnology laboratory operations experience. This individual will partner across scientific and business functions, lead internal and external resources, and drive practical improvements that support current and evolving research needs.</p>
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Senior Manager, Lab Operations

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<p><em>Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.</em></p>
<p><em>As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fscholarrock.com%2F&amp;esheet=54602249&amp;newsitemid=20260911564629&amp;lan=en-US&amp;anchor=ScholarRock.com&amp;index=10&amp;md5=af235377a7f0c8fbf451d85159f006ff"><strong>ScholarRock.com</strong></a> and follow @ScholarRock on X and on LinkedIn.</em></p>
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<div><strong style="font-size: 18px;">Summary of Position:</strong></div><div><br></div><div>
<p>The Director, reporting to the Senior Director, Market Insights, will be a member of the Business Operations and Analytics team, accountable for insight generation and competitive intelligence for a newly launched neuromuscular treatment with potential expansion into new indications. This role will serve as an organizational, strategic thought partner, enabling high-quality, data driven, evidence-based decision making.&nbsp; This is a high-impact, high-visibility role within a fast-growing organization and an opportunity to contribute to the Global commercial foundation of Scholar Rock’s first marketed product.</p>
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Director, Market Insights

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<p><em>Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.</em></p>
<p><em>As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fscholarrock.com%2F&amp;esheet=54602249&amp;newsitemid=20260911564629&amp;lan=en-US&amp;anchor=ScholarRock.com&amp;index=10&amp;md5=af235377a7f0c8fbf451d85159f006ff"><strong>ScholarRock.com</strong></a> and follow @ScholarRock on X and on LinkedIn.</em></p>
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<div><strong style="font-size: 18px;">Summary of Position:</strong></div><div><br></div><div>
<p>Scholar Rock is seeking an accomplished and highly collaborative leader in clinical bioanalysis to join the Bioanalytical Sciences team as <strong>Principal Scientist, Bioanalytical Specialist </strong>to provide scientific and operational leadership across our clinical stage programs.</p>
<p>Reporting to the Head of Bioanalytical Sciences, this individual will serve as a bioanalytical subject matter expert for our clinical stage programs, by representing the bioanalytical team at clinical study team meetings and providing oversight of clinical bioanalysis activities at CROs, including assay validation, sample analysis, data delivery, issue resolution, and inspection readiness, supporting strategic initiatives within the Bioanalytical and Preclinical Sciences teams. &nbsp;The Principal Scientist will partner cross-functionally with key parters in Discovery, Biomarker Development, Clinical Pharmacology, Clinical Sciences, Clinical Operations, and Regulatory to align bioanalytical strategy and execution with clinical development plans, regulatory expectations, and key program decisions. This individual will establish priorities and drive bioanalytical execution across multiple clinical programs in a dynamic, fast-paced environment.</p>
<p>The successful candidate will have demonstrated the ability to lead bioanalysis across all clinical stages, CRO management, and issue resolution. They will collaborate cross-functionally and provide scientific, strategic, and operational leadership for outsourced bioanalytical activities supporting Scholar Rock’s clinical-stage programs.</p>
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Principal Scientist, Bioanalytical Specialist

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<p><em>Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.</em></p>
<p><em>As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fscholarrock.com%2F&amp;esheet=54602249&amp;newsitemid=20260911564629&amp;lan=en-US&amp;anchor=ScholarRock.com&amp;index=10&amp;md5=af235377a7f0c8fbf451d85159f006ff"><strong>ScholarRock.com</strong></a> and follow @ScholarRock on X and on LinkedIn.</em></p>
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<div><strong style="font-size: 18px;">Summary of Position:</strong></div><div><br></div><div>
<p>Reporting to the Director of Payroll, the Payroll Manager plays a key part in Scholar Rock’s payroll function and ensuring employees are paid accurately, on time, and in compliance with applicable federal, state, local, and internal policy requirements. This role will have responsibility for payroll processing, tax and regulatory compliance, payroll records, audits, reconciliations, and payroll system administration. The Payroll Manager partners closely with Human Resources as well as other departments and external vendors to support a reliable and efficient payroll operation. The successful candidate will have a proven track record in processing multi-state payroll in a public company environment. This position will require a hands-on approach, strong organization, clear communication, attention to detail and a great sense of teamwork. This position represents a great opportunity to help build a critical function at a growing and evolving biotechnology company.</p>
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Payroll Manager

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<p><em>Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.</em></p>
<p><em>As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fscholarrock.com%2F&amp;esheet=54602249&amp;newsitemid=20260911564629&amp;lan=en-US&amp;anchor=ScholarRock.com&amp;index=10&amp;md5=af235377a7f0c8fbf451d85159f006ff"><strong>ScholarRock.com</strong></a> and follow @ScholarRock on X and on LinkedIn.</em></p>
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<div><strong style="font-size: 18px;">Summary of Position:</strong></div><div><br></div><div>
<p>Scholar Rock is seeking an accomplished and highly collaborative <strong>Principal Scientist, Biomarker Development,</strong> to provide scientific leadership for biomarker strategy and execution across preclinical programs in neuromuscular disease. Reporting to the Senior Director, Head of Biomarker Development, this individual will support the discovery, development, and implementation of fit-for-purpose biomarker approaches that enable translation from discovery through early clinical development.</p>
<p>The Principal Scientist will serve as a subject matter expert in biomarker and translational science, partnering closely with Discovery Biology, Bioanalytical, and Clinical Pharmacology and other cross-functional stakeholders. This individual will be responsible for developing biomarker strategies, defining context-of-use, guiding assay development and data generation, interpreting biomarker data, and contributing to program strategy.</p>
<p>The successful candidate will bring deep scientific expertise, strong strategic thinking, and hands-on experience translating biological hypotheses into clinically actionable biomarker approaches. They will integrate discovery, translational, and clinical perspectives to support assessment of target engagement, pharmacodynamic response, and neuromuscular disease biology and progression.</p>
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<h3>Position Responsibilities:&nbsp;</h3>
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Principal Scientist

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<p><em>Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.</em></p>
<p><em>As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fscholarrock.com%2F&amp;esheet=54602249&amp;newsitemid=20260911564629&amp;lan=en-US&amp;anchor=ScholarRock.com&amp;index=10&amp;md5=af235377a7f0c8fbf451d85159f006ff"><strong>ScholarRock.com</strong></a> and follow @ScholarRock on X and on LinkedIn.</em></p>
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<div><strong style="font-size: 18px;">Summary of Position:</strong></div><div><br></div><div>The Senior Clinical Trial Manager is responsible for all operational aspects of a clinical study from setup through final report, with support from Clinical Operations Leadership. Depending on the size of the study, the Clinical Trial Manager may coordinate the activities of several other clinical team members (e.g. Clinical Research Associates, Data Managers), as well as several external clinical vendors and/ or consultants. The Senior Clinical Trial Manager may also assume the role of the in-house Lead Clinical Research Associate for a study, as needed.</div>

Associate Director/Senior Clinical Trial Manager

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<p><em>Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.</em></p>
<p><em>As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fscholarrock.com%2F&amp;esheet=54602249&amp;newsitemid=20260911564629&amp;lan=en-US&amp;anchor=ScholarRock.com&amp;index=10&amp;md5=af235377a7f0c8fbf451d85159f006ff"><strong>ScholarRock.com</strong></a> and follow @ScholarRock on X and on LinkedIn.</em></p>
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<div><strong style="font-size: 18px;">Summary of Position:</strong></div><div><br></div><div>
<p>Scholar Rock is seeking a motivated, energetic, and outstanding individual with experience in clinical statistics to join our team.&nbsp;The Senior Manager/Associate Director, Biostatistics will participate in all biostatistics activities in a clinical development program from clinical design to regulatory submission. The Biostatistics function is an integral part of every step of clinical development at Scholar Rock, and the Senior Manager/Associate Director, Biostatistics plays a key role at the study level, and potentially at a clinical development program level. Key responsibilities include day-to-day clinical statistician activities, clinical trial design, statistical analysis development, carrying out modeling, simulation and analysis, and leading statistical deliverables.&nbsp;</p>
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Senior Manager /Associate Director, Biostatistics

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<p><em>Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.</em></p>
<p><em>As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fscholarrock.com%2F&amp;esheet=54602249&amp;newsitemid=20260911564629&amp;lan=en-US&amp;anchor=ScholarRock.com&amp;index=10&amp;md5=af235377a7f0c8fbf451d85159f006ff"><strong>ScholarRock.com</strong></a> and follow @ScholarRock on X and on LinkedIn.</em></p>
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<div><strong style="font-size: 18px;">Summary of Position:</strong></div><div><br></div><div>
<p>The (Senior) Medical Director, reporting to the VP, Clinical Research, will be a member of the clinical research team, accountable for driving clinical development activities for assigned pipeline products. The successful candidate will be responsible for providing medical leadership for clinical development activities in alignment with corporate strategy. This position requires a highly motivated physician scientist with hands-on expertise in advancing product candidates to deliver life-changing medicines.</p>
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Medical Director/Sr Director, Clinical Research

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<p><em>Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.</em></p>
<p><em>As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fscholarrock.com%2F&amp;esheet=54602249&amp;newsitemid=20260911564629&amp;lan=en-US&amp;anchor=ScholarRock.com&amp;index=10&amp;md5=af235377a7f0c8fbf451d85159f006ff"><strong>ScholarRock.com</strong></a> and follow @ScholarRock on X and on LinkedIn.</em></p>
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<div><strong style="font-size: 18px;">Summary of Position:</strong></div><div><br></div><div>
<p>Scholar Rock is looking for an experienced Senior Director, Device Engineering to be the company’s technical subject matter expert for combination products and drug delivery devices. This is a hands-on technical role, in which you will help shape and execute device engineering strategy for biologic assets, including the development of subcutaneous presentations using prefilled syringe (PFS) and autoinjector technologies, as well as drug delivery solutions for future pipeline assets.&nbsp;</p>
<p>You will lead key device development activities, including design controls, drug-device integration, assembly process development, characterization/validation, device risk analysis, design history file (DHF) management, verification and validation, design transfer and human factors engineering. You will also partner with Regulatory CMC on combination product regulatory activities and work closely with Drug Product Development, Drug Product External Manufacturing, Regulatory CMC, Quality Control, and Quality Assurance. This role includes the opportunity to lead external consultants and device partners and support oversight of device testing at contract test laboratories.</p>
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