Janux Therapeutics is a biopharmaceutical company focused on developing novel immunotherapies to treat cancer and other diseases. Leveraging cutting-edge technologies and innovative research, Janux Therapeutics aims to revolutionize the field of immunotherapy and provide new treatment options for patients worldwide.

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<div><span style="font-size: 11pt; color: black;">We are seeking a highly skilled and motivated Principal Scientist to join our Analytical and Formulation Development team. The successful candidate will lead and oversee analytical and formulation development activities for our pipeline of therapeutic candidates in immuno-oncology and autoimmune disease. This role requires a deep understanding of analytical methodologies, formulation development of biologics, regulatory requirements, as well as experience managing analytical development and QC activities at CDMOs.</span></div>

Principal Scientist, Analytical Development & Formulation

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<p>The Clinical Trial Associate (CTA) will provide operational support for the planning, execution, and closeout of clinical studies across Janux Therapeutics' clinical development programs. The CTA will partner closely with Clinical Trial Managers, Clinical Operations leadership, CROs, study vendors, and investigative sites to ensure studies are conducted in compliance with protocol requirements, ICH/GCP guidelines, regulatory requirements, and internal SOPs. This individual will be responsible for coordinating study documentation, maintaining inspection-ready Trial Master Files (TMFs), tracking study metrics, supporting study start-up and closeout activities, and facilitating communication among cross-functional stakeholders. The ideal candidate is highly organized, detail-oriented, proactive, and eager to grow within a fast-paced biotech environment.</p>
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Clinical Trial Associate

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<p>As a member of the pharmacology group, we seek a scientifically curious and motivated individual with an ability to work in a fast-paced environment. The potential Research Associate will develop and execute the ligand binding assay based bioanalytical method development to support pharmacokinetics (PK) sample analysis. In addition, the candidate will have opportunity to analyze high volume of data and to develop in vitro assays for compound characterization using ELISA, Octet, and cell-based assays. This position is hands-on and requires the effective experiment execution, communication, and documentation of results that enable the advancement of novel research molecules toward development candidates. Strong candidates will be hard working, efficient, collaborative, and passionate about drug discovery and development. Experience in ligand binding assay development and routine sample analysis is desired. This position will report directly to the Scientist of in vivo Pharmacology.</p>
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Research Associate, Pharmacology

<p>Our Analytical Development team is growing and we’re seeking a Senior Research Associate to participate in designing and executing experiments, as well as perform sample analysis utilizing HPLC, CE-SDS, iCIEF, and plate-based assays. These activities will support CMC, discovery, pre-clinical, and clinical development of existing and new lead candidates. This position will directly support the discovery of next-generation immune oncology drugs. It is a hands-on position that requires effective communication and documentation of results to enable the advancement of novel research molecules toward development of clinical candidates, which will ultimately lead to late-stage development and commercialization. Ideal applicants will be agile and highly driven, collaborative, team-oriented, possess excellent communication and organization skills, and carry a strong commitment to excellence.</p>

Senior Research Associate, Analytical Development

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<p>The Senior Manager, Clinical Contracts will ensure the successful negotiation and ongoing management of clinical trial-related agreements and serve as the key liaison between Clinical Operations, Legal, Finance and Accounting departments. This role involves but is not limited to generating, reviewing, finalizing and tracking contracts and budgets, and managing cross-functional communication. This individual will be expected to support the clinical team in the planning, execution and control of contracts. The ideal candidate tasks effectively and applies critical thinking to resolve challenges while maintaining clear communication.</p>
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Senior Manager, Clinical Contracts

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<p>The Senior/Clinical Trial Manager will be responsible for managing and executing operational aspects of assigned clinical trials, from study start-up to close-out, with a focus on autoimmune studies. This individual will be instrumental in managing and overseeing CROs, study vendors, and clinical trial sites, while partnering with key internal stakeholders to ensure clinical trial deliverables are completed on time, within budget, and in accordance with regulatory requirements, GCP guidelines, and internal SOPs. This position reports directly to the Senior Director of Clinical Operations and serves as an integral member of the Clinical Operations team, contributing to the development of trial strategy, executing initiatives, and ensuring the highest standards in operational delivery. This is a great opportunity to make a meaningful impact in a fast-paced, mission-driven biotech environment.</p>
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Clinical Trial Manager/Senior Clinical Trial Manager

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<p>An integral member of the Janux Therapeutics’ Clinical Development team; the Director, Clinical Science will &nbsp;support the strategic planning and execution of clinical-stage programs for one of the the company’s early stage oncology platforms. This role partners closely with Clinical Operations to ensure effective trial conduct and supports the Clinical Lead in delivering critical trial milestones.</p>
<p>This role is perfect for individuals passionate about science-driven strategy and want to be at the forefront of immunotherapy innovation, as their opportunity to make a difference.</p>
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Director, Clinical Science

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<p style="margin: 0in 0in 8pt; line-height: 115%; font-size: 12pt; font-family: Aptos, sans-serif;">Janux Therapeutics is seeking a Senior Director, Clinical Supply Chain will lead and execute Janux’s clinical supply strategy across Phase 1–3 programs, with a focus on enabling progression into late-stage development. This is a hands-on leadership role responsible for ensuring uninterrupted global supply of investigational medicinal product (IMP) while building scalable processes to support growing clinical program complexity.</p>
<p style="margin: 0in 0in 8pt; line-height: 115%; font-size: 12pt; font-family: Aptos, sans-serif;">This role partners closely with Clinical Operations, CMC, Quality, and Regulatory to align supply planning, manufacturing, and trial execution. The ideal candidate brings deep experience in biologics and global clinical trial supply, including hands-on support of late-stage clinical programs in a fast-paced biopharma environment.</p>
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Senior Director, Clinical Supply Chain

<p>The Associate Director, Clinical Operations will be responsible for managing operational aspects of assigned clinical trials, with a focus on early-phase oncology studies. This includes oversight of contract research organizations (CROs), vendors, and clinical sites across both U.S. and international regions. The role requires a deep understanding of clinical trial processes, regulatory compliance (GCP, FDA, ICH), and the ability to lead cross-functional teams to ensure high-quality, timely, and cost-effective trial execution. The ideal candidate will bring an in-depth understanding of managing early phase oncology trials at a sponsor biotech.</p>

Associate Director, Clinical Operations

<div><span style="font-size: 11pt;">The Senior Director of Clinical Operations will provide global operational leadership overseeing complex clinical programs focusing on innovative T-cell engager therapies for immunology indications. This role is responsible for efficient planning, resourcing and execution of portfolio level programs in adherence to ICH-GCP, FDA regulations, and company SOPs. The Senior Director will report into the Vice President, Clinical Operations and will ensure strategic alignment of programs and key stakeholder management in a fast-paced environment, while mentoring and growing the Clinical Operations team and culture to ensure successful program delivery.</span></div>

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