Janux Therapeutics is a biopharmaceutical company focused on developing novel immunotherapies to treat cancer and other diseases. Leveraging cutting-edge technologies and innovative research, Janux Therapeutics aims to revolutionize the field of immunotherapy and provide new treatment options for patients worldwide.

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<div>Janux Therapeutics is seeking an Executive Director, Head of Bioinformatics, to build, lead, and scale a best‑in‑class bioinformatics and computational biology function supporting our discovery, translational, and clinical development programs across oncology and immunology.</div><div>This is a hands‑on scientific leadership role for a seasoned bioinformatics leader who can operate as both strategist and technical expert. The Executive Director will define Janux’s bioinformatics vision, own multi‑omic and computational strategies from discovery through early clinical development, and serve as a key scientific partner across Research, Translational Medicine, Biometrics, and Clinical Development.</div>

Executive Director, Head of Bioinformatics

<div>Janux Therapeutics is seeking a Director of FP&amp;A to serve as a strategic finance partner for clinical organization. This role will lead budgeting, forecasting, and long‑range planning while ensuring financial systems, models, and data integrity scale with the organization. The ideal candidate brings deep FP&amp;A experience in a biotech or life sciences environment, strong systems administration experience (Adaptive preferred), and experience planning and executing clinical trials (Oncology and/or Autoimmune preferred).</div>

Director, Financial Planning & Analysis

<div> <p style="margin: 0in; background: white; font-size: 12pt; font-family: 'Times New Roman', serif;"><span style="font-size: 11.0pt; font-family: Calibri, sans-serif; color: black;">Janux Therapeutics is seeking a highly motivated Research Associate/Sr. Research Associate with experience working in immunology or oncology in a clinical laboratory or CRO settings. The incumbent will be an integral member of the clinical immunology team and will work on flow-based assays for Janux’s TRACTr and TRACIr clinical programs. An ideal candidate will have hands-on experience with flow cytometry, T cell activation, assay development and optimization.</span></p> <p style="margin: 0in; background: white; font-size: 12pt; font-family: 'Times New Roman', serif;">&nbsp;</p> <p style="margin: 0in; background: white; font-size: 12pt; font-family: 'Times New Roman', serif;"><span style="font-size: 11.0pt; font-family: Calibri, sans-serif; color: black;">This position is hands-on bench work and requires effective communication and documentation of results. The ideal applicant will be collaborative and team-oriented, self-motivated, possess excellent communication and organizational skills, and carry a strong commitment to excellence.</span></p> </div>

Research Associate / Sr. Research Associate, Clinical Immunology

<div>Janux Therapeutics is seeking a highly motivated Principal Scientist with demonstrated skills in the field of cancer immunology and/or immune cell biology. The incumbent will develop and troubleshoot cell-based assays for pre-clinical programs. These studies will aid in better understanding of MoA and in differentiation from competition. This person will mentor or manage more junior members in the immunology team, as well as interact closely with members across functional teams. A successful candidate will have extensive hands-on experience with assay development and troubleshooting, lead the immunology team in laboratory research to ensure timelines are met, inspire and develop team members, and be accountable for meeting deliverables for the Immunology team. This position is approximately 30-50% hands-on bench work and requires the effective communication and documentation. The ideal applicant will be collaborative and team-oriented, self-motivated, possess excellent communication and organizational skills, and carry a strong commitment to excellence.</div> <div>&nbsp;</div> <div>This position is approximately 30-50% hands-on bench work and requires the effective communication and documentation. The ideal applicant will be collaborative and team-oriented, self-motivated, possess excellent communication and organizational skills, and carry a strong commitment to excellence.</div>

Principal / Senior Scientist, Immunology

<div> <p>The Senior Manager, Pharmacovigilance will be responsible for the execution and oversight of pharmacovigilance activities for Janux programs. This individual will ensure compliance with global safety regulations and support the identification, evaluation and communication of safety information across all Janux programs. This role combines strategic oversight with hands-on execution, ensuring integration of safety into drug development. The Senior Manager will also serve as a key liaison with internal and external stakeholders.</p> </div>

Senior Manager, Pharmacovigilance

<div> <p>Janux Therapeutics is seeking a Project Team Leader (PTL) to provide visionary leadership and strategic direction for the development and execution of Integrated Asset Plans across our oncology and autoimmune portfolio. The PTL will serve as the single point of accountability for the seamless delivery of project milestones and outcomes for one or more assets, guiding them from First-in-Human/First-in-Patient (FIH/FIP) studies through Phase 1–3 clinical development and comprehensive life-cycle management.</p> <p>This role requires a leader with exceptional expertise in oncology drug development, a proven ability to drive cross-functional teams, optimizing team alignment, governance, and overall team health. The PTL will be entrusted with critical oversight of asset budgets, investment recommendations, and continuous optimization of asset strategies, ensuring alignment with Janux’s broader portfolio objectives.</p> </div>

Project Team Lead

<div> <p>Janux Therapeutics is seeking a paralegal to support the Legal Department across a broad range of corporate, securities, contracts, and compliance matters, with a focus on the unique needs of a public, clinical‑stage biotechnology company. This role requires exceptional organizational skills, attention to detail, and the ability to work independently in a fast‑paced, collaborative environment.</p> <p>The ideal candidate brings strong experience in contract administration, corporate governance and legal operations, and is comfortable partnering cross‑functionally with Finance, HR, Business Development, and external counsel.</p> </div>

Paralegal

<div><span style="font-size: 11pt;">The Senior Director of Clinical Operations will provide global operational leadership overseeing complex clinical programs focusing on innovative T-cell engager therapies for immunology indications. This role is responsible for efficient planning, resourcing and execution of portfolio level programs in adherence to ICH-GCP, FDA regulations, and company SOPs. The Senior Director will report into the Vice President, Clinical Operations and will ensure strategic alignment of programs and key stakeholder management in a fast-paced environment, while mentoring and growing the Clinical Operations team and culture to ensure successful program delivery.</span></div>

Senior Director, Clinical Operations (autoimmune)

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<p>Reporting to the Chief Medical Officer, the Vice President, Biometrics will lead and oversee all biometrics activities supporting clinical development from IND-enabling studies through regulatory submission. This role is responsible for Biostatistics, Statistical Programming, and Clinical Data Management, and will serve as the functional head of Biometrics at Janux.</p>
<p>The VP will work closely with senior leadership to shape clinical strategy, study design, regulatory planning, and data-driven decision-making. This role requires a highly strategic and collaborative leader who can also operate hands-on in a dynamic, fast-paced clinical-stage biotech environment.</p>
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Vice President, Biometrics

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<p>The Enterprise Applications Administrator plays a key role in supporting and optimizing key business and scientific applications at Janux Therapeutics. This individual will serve as a technical resource for administering enterprise platforms, managing user environments, and ensuring reliable system performance that support both corporate and scientific operations. This role requires experience managing Microsoft Office365, Azure, and both on-premise and cloud-based systems. Superior troubleshooting skills will be required for issues related to deployment, updates, and ongoing use of business-critical software. Experience in biotech or lab-based environments is highly desirable.</p>
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