Janux Therapeutics is a biopharmaceutical company focused on developing novel immunotherapies to treat cancer and other diseases. Leveraging cutting-edge technologies and innovative research, Janux Therapeutics aims to revolutionize the field of immunotherapy and provide new treatment options for patients worldwide.

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<p>Reporting to the Chief Medical Officer, the Vice President, Biometrics will lead and oversee all biometrics activities supporting clinical development from IND-enabling studies through regulatory submission. This role is responsible for Biostatistics, Statistical Programming, and Clinical Data Management, and will serve as the functional head of Biometrics at Janux.</p>
<p>The VP will work closely with senior leadership to shape clinical strategy, study design, regulatory planning, and data-driven decision-making. This role requires a highly strategic and collaborative leader who can also operate hands-on in a dynamic, fast-paced clinical-stage biotech environment.</p>
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Vice President, Biometrics

<div><span style="font-size: 11pt;">Janux Therapeutics is seeking a strategic and accomplished Manager / Senior Manager, Talent Acquisition to drive our recruitment efforts in a dynamic, high-growth biotechnology environment. As a key partner to our Talent Acquisition and Human Resources teams, you will own the full lifecycle of talent acquisition, shaping and executing strategies that attract, engage, and secure top-tier talent aligned with Janux’s mission and values.</span></div>

Manager / Senior Manager, Talent Acquisition

<div><span style="font-size: 11pt;">To support our growth, Janux Therapeutics is searching for a Senior Manager of Data Management to manage day-to-day operations of data management activities. The Senior Manager will ensure compliance with regulatory requirements and industry standards to improve operational efficiency.&nbsp; They will also manage activities with vendors to support our oncology clinical trials and maintain high quality data management deliverables in a timely manner.</span></div><div><span style="font-size: 11pt;">This role needs a proactive, and resourceful professional who has strong experience in hands-on data management activities within oncology indications.</span></div>

Senior Manager, Data Management

<div><span style="font-size: 11pt;">The Director of Corporate Strategy and Analytics will lead strategic initiatives that define Janux’s long-term growth trajectory. This role integrates corporate strategy, market insights, and analytics to ensure alignment across research, clinical development, and commercialization. The ideal candidate will have strong analytical capabilities, deep biopharma industry knowledge, preferably in oncology and autoimmune, and proven leadership skills to influence decisions at the highest levels.&nbsp;&nbsp;</span></div>

Director, Corporate Strategy and Analytics

<div>Janux Therapeutics is seeking a Clinical Biomarker Lead to join our Translational group and contribute hands-on in the development and execution of biomarker analysis plans and data analytics strategy for our early-stage oncology programs. This individual will develop critical insights from clinical trial data to inform strategic decision-making across Janux’s early phase portfolio. The ideal candidate will bring an in-depth understanding of solid tumor immunology and clinical-translational research experience.&nbsp;</div>

Clinical Biomarker Lead

<div><span style="font-size: 11pt;">Janux Therapeutics is seeking a Senior Research Associate to participate in designing and executing experiments, as well as perform sample analysis utilizing HPLC, CE-SDS, iCIEF, and capillary CE-SDS ELISA [simple western blot (Jess)]. These activities will support CMC, discovery, pre-clinical, and clinical development of existing and new lead candidates. This hands-on position requires effective communication and documentation of results to enable the advancement of novel research molecules toward development of clinical candidates, which will ultimately lead to late-stage development and commercialization. This position will directly support the discovery of next-generation immune oncology drugs. Ideal applicants will be agile and highly driven, collaborative, team-oriented, possess excellent communication and organizational skills, and carry a strong commitment to excellence.</span></div>

Senior Research Associate, Analytical Development

<div>The Senior Payroll Manager will be responsible for overseeing and executing all aspects of payroll operations for Janux Therapeutics, ensuring accurate, timely, and compliant payroll processing across the organization. This role will serve as a key partner to Finance and Human Resources, with a strong focus on compliance, confidentiality, process integrity, and operational excellence in a fast‑paced biotech environment.</div>

Senior Payroll Manager

<div><span style="font-size: 11pt;">The Director, Global Regulatory Affairs will play a critical role in developing and implementing regulatory strategies to support the global development and expansion of Janux’s clinical pipeline. This player-coach individual will work closely with cross-functional teams to ensure compliance with regulatory requirements and to achieve successful regulatory approvals.</span></div>

Director, Global Regulatory Affairs

<div><span style="font-size: 11pt;">The Vice President, Regulatory Affairs &amp; Quality Assurance will provide strategic and operational leadership across Regulatory and Quality functions in Janux’s growing biotech environment. This individual will be responsible for developing and executing regulatory and quality strategies that enable efficient advancement of the company’s pipeline from early development through commercialization, while ensuring sustained compliance with global regulatory and GxP requirements.</span></div><div><span style="font-size: 11pt;">Reporting to the Chief Medical Officer, the VP will be a key partner to clinical development, CMC, manufacturing, and commercial teams and will represent the company in interactions with global health authorities.</span></div>

Vice President, Regulatory Affairs and Quality Assurance

<div><span style="font-size: 11pt">The Executive Assistant to the Chief Medical Officer (CMO) will serve as a highly trusted, proactive, and detail‑obsessed partner to one of Janux’s critical executive leaders. This individual will ensure the CMO’s office operates with exceptional precision, consistency, commitment and professionalism. The ideal candidate is anticipatory by nature, thrives in a high‑expectation environment, and can manage a complex, evolving workload with composure and impeccable judgment in a clinical stage biotech.</span></div><div><br></div><div><span style="font-size: 11pt"> The best candidate for this role is proactive, agile, organized, and calm under pressure. They are exceptional communicators with strong interpersonal and collaborative skills, comfortable engaging with senior leaders, cross-functional partners, and external stakeholders including all levels of leaders in academia, finance and business. You must thrive in a fast-paced environment, stay highly organized, and have a can-do attitude where nothing is outside the job description.</span></div><div><br></div><div><span style="font-size: 11pt"> The EA will also collaborate closely with Clinical Development, Regulatory, Clinical Sciences and Operations teams cross functionally, providing additional leaders support depending on departmental needs.</span></div>

Executive Assistant

<div><span style="font-size: 11pt">The Senior Director of Clinical Operations will provide global operational leadership overseeing complex clinical programs focusing on innovative T-cell engager therapies for oncology or immunology indications. This role is responsible for efficient planning, resourcing and execution of portfolio level programs in adherence to ICH-GCP, FDA regulations, and company SOPs. The Senior Director will report into the Vice President, Clinical Operations and will ensure strategic alignment of programs and key stakeholder management in a fast-paced environment, while mentoring and growing the Clinical Operations team and culture to ensure successful program delivery.</span></div>

Senior Director, Clinical Operations

<div>The Vice President of Global Medical Affairs will provide strategic and hands-on leadership for Janux. Therapeutics. This role will be highly external-facing and execution-driven, responsible for shaping scientific narrative, building key external relationships, and ensuring high-quality, compliant medical engagement as Janux advances its clinical-stage oncology programs. The VP, Medical Affairs will report directly to the Chief Medical Officer, and partner closely with&nbsp;Clinical Development, Regulatory, Translational Science, and Commercial colleagues to ensure strong alignment between clinical strategy, external scientific exchange, and future commercialization readiness.</div>

Vice President, Medical Affairs

<div><span style="font-size: 11pt;">Janux Therapeutics is seeking a detail-oriented Accountant to support core accounting activities across the organization, including support of clinical and research programs. This role prepares monthly accruals, journal entries, and balance sheet reconciliations, while partnering cross‑functionally with teams such as Clinical Operations, Legal, and other internal stakeholders to ensure accurate and timely financial reporting. This position will report to the </span><s><span style="font-size: 11pt;">Senior Director of </span></s><span style="font-size: 11pt;">Accounting Manager and is responsible for performing a range of accounting activities in compliance with Generally Accepted Accounting Practices (GAAP), Sarbanes Oxley (SOX), and organization-wide policies and procedures. &nbsp;&nbsp;</span></div><div><span style="font-size: 11pt;">&nbsp;</span></div><div><span style="font-size: 11pt;">The ideal candidate will be a team-player who is detail-orientated, self-motivated, and possesses strong interpersonal, communication and organizational skills.&nbsp;</span></div>

Senior Accountant

<div>Janux Therapeutics is seeking an Executive Director, Head of Bioinformatics, to build, lead, and scale a best‑in‑class bioinformatics and computational biology function supporting our discovery, translational, and clinical development programs across oncology and immunology.</div><div>This is a hands‑on scientific leadership role for a seasoned bioinformatics leader who can operate as both strategist and technical expert. The Executive Director will define Janux’s bioinformatics vision, own multi‑omic and computational strategies from discovery through early clinical development, and serve as a key scientific partner across Research, Translational Medicine, Biometrics, and Clinical Development.</div>

Executive Director, Head of Bioinformatics

<div>Janux Therapeutics is seeking a Director of FP&amp;A to serve as a strategic finance partner for clinical organization. This role will lead budgeting, forecasting, and long‑range planning while ensuring financial systems, models, and data integrity scale with the organization. The ideal candidate brings deep FP&amp;A experience in a biotech or life sciences environment, strong systems administration experience (Adaptive preferred), and experience planning and executing clinical trials (Oncology and/or Autoimmune preferred).</div>

Director, Financial Planning & Analysis

<div> <p style="margin: 0in; background: white; font-size: 12pt; font-family: 'Times New Roman', serif;"><span style="font-size: 11.0pt; font-family: Calibri, sans-serif; color: black;">Janux Therapeutics is seeking a highly motivated Research Associate/Sr. Research Associate with experience working in immunology or oncology in a clinical laboratory or CRO settings. The incumbent will be an integral member of the clinical immunology team and will work on flow-based assays for Janux’s TRACTr and TRACIr clinical programs. An ideal candidate will have hands-on experience with flow cytometry, T cell activation, assay development and optimization.</span></p> <p style="margin: 0in; background: white; font-size: 12pt; font-family: 'Times New Roman', serif;">&nbsp;</p> <p style="margin: 0in; background: white; font-size: 12pt; font-family: 'Times New Roman', serif;"><span style="font-size: 11.0pt; font-family: Calibri, sans-serif; color: black;">This position is hands-on bench work and requires effective communication and documentation of results. The ideal applicant will be collaborative and team-oriented, self-motivated, possess excellent communication and organizational skills, and carry a strong commitment to excellence.</span></p> </div>

Research Associate / Sr. Research Associate, Clinical Immunology

<div>Janux Therapeutics is seeking a highly motivated Principal Scientist with demonstrated skills in the field of cancer immunology and/or immune cell biology. The incumbent will develop and troubleshoot cell-based assays for pre-clinical programs. These studies will aid in better understanding of MoA and in differentiation from competition. This person will mentor or manage more junior members in the immunology team, as well as interact closely with members across functional teams. A successful candidate will have extensive hands-on experience with assay development and troubleshooting, lead the immunology team in laboratory research to ensure timelines are met, inspire and develop team members, and be accountable for meeting deliverables for the Immunology team. This position is approximately 30-50% hands-on bench work and requires the effective communication and documentation. The ideal applicant will be collaborative and team-oriented, self-motivated, possess excellent communication and organizational skills, and carry a strong commitment to excellence.</div> <div>&nbsp;</div> <div>This position is approximately 30-50% hands-on bench work and requires the effective communication and documentation. The ideal applicant will be collaborative and team-oriented, self-motivated, possess excellent communication and organizational skills, and carry a strong commitment to excellence.</div>

Principal / Senior Scientist, Immunology

<div> <p>The Senior Manager, Pharmacovigilance will be responsible for the execution and oversight of pharmacovigilance activities for Janux programs. This individual will ensure compliance with global safety regulations and support the identification, evaluation and communication of safety information across all Janux programs. This role combines strategic oversight with hands-on execution, ensuring integration of safety into drug development. The Senior Manager will also serve as a key liaison with internal and external stakeholders.</p> </div>

Senior Manager, Pharmacovigilance

<div> <p>Janux Therapeutics is seeking a Project Team Leader (PTL) to provide visionary leadership and strategic direction for the development and execution of Integrated Asset Plans across our oncology and autoimmune portfolio. The PTL will serve as the single point of accountability for the seamless delivery of project milestones and outcomes for one or more assets, guiding them from First-in-Human/First-in-Patient (FIH/FIP) studies through Phase 1–3 clinical development and comprehensive life-cycle management.</p> <p>This role requires a leader with exceptional expertise in oncology drug development, a proven ability to drive cross-functional teams, optimizing team alignment, governance, and overall team health. The PTL will be entrusted with critical oversight of asset budgets, investment recommendations, and continuous optimization of asset strategies, ensuring alignment with Janux’s broader portfolio objectives.</p> </div>

Project Team Lead

<div> <p>Janux Therapeutics is seeking a paralegal to support the Legal Department across a broad range of corporate, securities, contracts, and compliance matters, with a focus on the unique needs of a public, clinical‑stage biotechnology company. This role requires exceptional organizational skills, attention to detail, and the ability to work independently in a fast‑paced, collaborative environment.</p> <p>The ideal candidate brings strong experience in contract administration, corporate governance and legal operations, and is comfortable partnering cross‑functionally with Finance, HR, Business Development, and external counsel.</p> </div>

Paralegal

<div><span style="font-size: 11pt;">The Senior Director of Clinical Operations will provide global operational leadership overseeing complex clinical programs focusing on innovative T-cell engager therapies for immunology indications. This role is responsible for efficient planning, resourcing and execution of portfolio level programs in adherence to ICH-GCP, FDA regulations, and company SOPs. The Senior Director will report into the Vice President, Clinical Operations and will ensure strategic alignment of programs and key stakeholder management in a fast-paced environment, while mentoring and growing the Clinical Operations team and culture to ensure successful program delivery.</span></div>

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