Gossamer Bio is a biopharmaceutical company dedicated to discovering, developing, and delivering innovative therapeutics to address high unmet medical needs. With a focus on immunology and inflammation, Gossamer Bio aims to advance cutting-edge treatments that can make a meaningful impact on patients' lives.

SUMMARY: Gossamer Bio has an outstanding opportunity for a motivated and accomplished computational biology leader to join our lean Translational Science team. We are seeking a visionary bioinformatics leader who thrives at the intersection of biology, technology, and data science. This is a chance to build and drive cutting-edge translational bioinformatics, leveraging AI/Machine Learning and multi-omics innovation to transform clinical development and precision medicine. The successful candidate will join a biotech environment that values creativity, impact, and rapid execution, and will partner closely with Translational Medicine, Research, and Clinical Development teams to shape the next generation of patient-centric therapeutics. Essential Duties and Responsibilities Lead the analysis of clinical biomarker data by developing and executing exploratory biomarker analysis plans&nbsp;(genetics, proteomics, RNA‑seq/single-cell, imaging), including pre-specification of hypotheses, endpoints, and statistical methodologies Support clinical development programs by ensuring exploratory biomarker results, analyses and deliverables meet project timelines and regulatory-grade expectations, if applicable&nbsp;(data integrity, traceability, documentation) Collaborate with interdisciplinary teams (Clinical, Research, Biostats) to perform (hands-on) and/or direct multi-omics data analyses and integration across various domains and apply best-in-class algorithms to directly address the motivating biological and clinical questions.&nbsp; Drive innovation by applying advanced bioinformatics, data science, machine learning (ML) and Artificial Intelligence (AI) methods to interrogate high-dimensional datasets, enabling mechanism-of-action insights, drug response biomarkers, and data-driven patient stratification. Effectively lead bioinformatics CRO relationships by developing work plans, fostering efficient communication and ensuring high-quality deliverables. Translate complex findings into clear narratives for clinical teams, governance and external audiences (posters/manuscripts) Develop and scale the translational bioinformatics and AI platform and strategy, building a lean, high-impact team and external network to support future pipeline growth JOB QUALIFICATIONS Education, Certifications, Experience Required: Ph.D. (or equivalent experience) in computational biology, bioinformatics or biostatistics with 10+ years of biotech industry experience and a strong publication record in peer-reviewed journals. Expertise in next-generation sequencing algorithms, pipelines and applications (including single cell genomics) Strong coding skills (eg. R, Python) with an excellent working knowledge of public bioinformatics databases, emerging technologies and reproducible research practices. Experience in pulmonary disease, fibrosis, inflammation, immunology and/or cardiovascular biology. Scientific curiosity and creativity, with an ability to identify questions that computational approaches can address, and the skills to develop solutions both independently and collaboratively. Demonstrated experience in evaluating and executing data science algorithms and machine learning/AI models. Proven ability to bridge computation and biology, with an entrepreneurial mindset and track record of driving innovation from concept to clinical impact. A deep understanding of biology and the drivers of human disease would be a plus. Strong communication (written and verbal), data presentation and visualization skills. Experience leading productive collaborative relationships, including remotely and across cultures. Comfortable communicating science and influencing strategic decisions at all levels. Office environment/Remote/Hybrid Gossamer Bio is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants and complies with all applicable national, state and local laws governing nondiscrimination in employment. &nbsp;The expected salary range for this position is listed below. Actual pay will be determined based on experience, qualifications, and other job-related factors permitted by law. &nbsp;This position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. This position also qualifies for the benefits as listed below.Gossamer Bio offers highly competitive benefit plans and programs, including medical, dental and vision insurance, 401(k) and 401(k) matching , long-term incentive plan, disability plan, vacation pay, sick time, holiday pay, and work, personal and family time off in accordance with the terms of the applicable plans. For additional general information on Company benefits, please visit https://www.gossamerbio.com/work-at-gossamerbio/Pay Range$231,000&mdash;$272,000 USDCalifornia Consumer Privacy Act (CCPA) Notice for California Residents:This notice is to notify you that personal data about you has been collected by Gossamer Bio (“Controller”), which is located at 3115 Merryfield Row, Suite 120, San Diego CA 92121 and can be contacted by emailing privacy@gossamerbio.com, because Controller wishes to evaluate your candidacy for employment at Controller. Your personal data was either obtained from publicly available sources (e.g. LinkedIn) or provided to Controller by someone who referred you for potential employment. &nbsp;Controller’s Privacy team can be contacted at privacy@gossamerbio.com. &nbsp;Your personal data will be processed for the purposes of managing Controller’s recruitment related activities, which include setting up and conducting interviews and tests for applicants, evaluating and assessing the results thereto, and as is otherwise needed in the recruitment and hiring processes. &nbsp;Such processing is legally permissible under Art. 6(1)(f) of Regulation (EU) 2016/679 (General Data Protection Regulation) and the California Consumer Privacy Act (CCPA) as necessary for the purposes of the legitimate interests pursued by the Controller, which are the solicitation, evaluation, and selection of applicants for employment. Your personal data has been shared with Greenhouse Software, Inc., a cloud services provider located in the United States of America and engaged by Controller to help manage its recruitment and hiring process on Controller’s behalf. &nbsp;&nbsp; Your personal data will be retained by Controller as long as Controller determines it is necessary to evaluate your application for employment. &nbsp;Under the GDPR and CCPA, you have the right to request access to your personal data, to request that your personal data be rectified or erased, and to request that processing of your personal data be restricted. &nbsp;You also have to right to data portability. &nbsp;In addition, you may lodge a complaint with a supervisory authority.

Director/Senior Director Translational Bioinformatics

SUMMARY: We are seeking a highly capable bioinformatics expert to join our Translational Medicine team as a Principal Scientist, Bioinformatics. This individual will serve as a senior technical leader within the Bioinformatics function, driving high-impact biomarker and multi-omics analyses across Gossamer’s clinical programs in pulmonary disease. &nbsp;The role involves developing and executing advanced analytical workflows, contributing to biomarker hypothesis generation, and supporting cross-functional program teams from late-stage discovery through clinical development. The successful candidate will step into active therapeutic programs and operate with a high degree of independence, contributing meaningfully to program-level strategy and execution. This role requires close collaboration with Translational Research and Medicine, Clinical Development, Biostatistics, Medical Affairs and Regulatory Affairs, as well as engagement with external partners, thought leaders and CROs. Essential Duties and Responsibilities Lead computational biology and bioinformatics efforts within active therapeutic programs. Partner closely with Translational Research, Clinical Development and Biometrics to shape biomarker strategies and analysis plans. Perform study-level analyses of exploratory clinical biomarker data (including proteomics, transcriptomics, imaging) to assess mechanism of action, identify molecular drivers of remission and characterize therapeutic response. Conduct analyses to support preclinical translational research and exploratory biology studies to inform clinical development programs and business development objectives, including mechanism validation, target assessment, and responder biology. Develop and apply ML/AI models to characterize patient trajectories and identify responder subgroups Generate high-quality data visualizations, summaries, and analyses to support manuscripts, abstracts, regulatory submissions and internal communication and decision-making. Communicate findings clearly and effectively to both technical and non-technical stakeholders, contributing to program strategy and direction. Serve as a computational thought partner to scientific leadership across programs. JOB QUALIFICATIONS Required: Ph.D. in Bioinformatics, Computational Biology, Systems Biology, Biostatistics or related field. 5-10+ years of relevant experience in biotech or pharmaceutical industry roles, ideally supporting therapeutic development programs. Strong understanding of biology and translational research, with demonstrated ability to address biological questions using computational approaches. Demonstrated experience in analysis and biological interpretation of multi-omics datasets, including RNAseq, proteomics, single-cell, spatial, imaging, etc Strong proficiency in statistical modeling, machine learning and integrative data analysis Excellent programming skills in R and/or Python; experience with cloud computing environments Ability to work independently, manage priorities across programs, and influence program strategy through data-driven insights. Strong communication and collaboration skills, with experience working in matrixed, cross-functional teams. Preferred: Experience in pulmonary disease, fibrosis, inflammation, immunology and/or cardiovascular biology. Demonstrated track record of peer-reviewed publications and conference presentations Formal training or strong background in statistics Gossamer Bio is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants and complies with all applicable national, state and local laws governing nondiscrimination in employment.The expected salary range for this position is listed below. Actual pay will be determined based on experience, qualifications, and other job-related factors permitted by law. &nbsp;This position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. This position also qualifies for the benefits as listed below.Gossamer Bio offers highly competitive benefit plans and programs, including medical, dental and vision insurance, 401(k) and 401(k) matching , long-term incentive plan, disability plan, vacation pay, sick time, holiday pay, and work, personal and family time off in accordance with the terms of the applicable plans. For additional general information on Company benefits, please visit https://www.gossamerbio.com/work-at-gossamerbio/Pay Range$181,000&mdash;$195,000 USDCalifornia Consumer Privacy Act (CCPA) Notice for California Residents:This notice is to notify you that personal data about you has been collected by Gossamer Bio (“Controller”), which is located at 3115 Merryfield Row, Suite 120, San Diego CA 92121 and can be contacted by emailing privacy@gossamerbio.com, because Controller wishes to evaluate your candidacy for employment at Controller. Your personal data was either obtained from publicly available sources (e.g. LinkedIn) or provided to Controller by someone who referred you for potential employment. &nbsp;Controller’s Privacy team can be contacted at privacy@gossamerbio.com. &nbsp;Your personal data will be processed for the purposes of managing Controller’s recruitment related activities, which include setting up and conducting interviews and tests for applicants, evaluating and assessing the results thereto, and as is otherwise needed in the recruitment and hiring processes. &nbsp;Such processing is legally permissible under Art. 6(1)(f) of Regulation (EU) 2016/679 (General Data Protection Regulation) and the California Consumer Privacy Act (CCPA) as necessary for the purposes of the legitimate interests pursued by the Controller, which are the solicitation, evaluation, and selection of applicants for employment. Your personal data has been shared with Greenhouse Software, Inc., a cloud services provider located in the United States of America and engaged by Controller to help manage its recruitment and hiring process on Controller’s behalf. &nbsp;&nbsp; Your personal data will be retained by Controller as long as Controller determines it is necessary to evaluate your application for employment. &nbsp;Under the GDPR and CCPA, you have the right to request access to your personal data, to request that your personal data be rectified or erased, and to request that processing of your personal data be restricted. &nbsp;You also have to right to data portability. &nbsp;In addition, you may lodge a complaint with a supervisory authority.

Principal Scientist Bioinformatics

Summary: The Associate Director/Director, HR Operations is a key member of the HR team, responsible for scaling and governing efficient, compliant, and employee-centric HR operational services across a growing life-sciences organization. This role ensures HR infrastructure, systems, and workforce processes—spanning employees, contingent workers, and global employment partners—are scalable, compliant, and aligned to a regulated, commercialization-ready environment.&nbsp;The Associate Director / Director balances hands-on execution with strategic oversight to&nbsp; organizational growth, evolving workforce models, and global expansion. Key Responsibilities HR Operations &amp; Service Delivery Lead end-to-end HR operational processes across the employee lifecycle (offers, onboarding, offboarding, job changes, promotions, performance cycles, and data governance). Provide strategic oversight of employee benefits administration, ensuring accurate enrollment, eligibility management, vendor coordination, and compliance with applicable regulations. Oversee the preparation, review, and issuance of employment offer letters. Own and govern background check and pre-employment screening processes for U.S. and global hires, including vendor oversight, process standardization, and compliance with local regulations. Lead a fit-for-purpose HR operations model (in‑house, shared services, and/or vendor‑supported) that scales with commercialization and geographic growth. Ensure process standardization across global and multi-state operations Provide direct people leadership to HR Operations team members, including full-time employees and contractors, setting clear expectations, goals, and accountability. Contingent Workforce Management Provide operational leadership and governance for an established contingent workforce program, including consultants, contractors, temporary staff, and vendor-provided resources. Oversee standardized onboarding and offboarding processes for contingent workers, ensuring appropriate documentation, system access, training requirements, and security controls. Partner with Talent Acquisition, Contracts, Finance, IT, and Hiring Managers to support proper worker classification, contract management, and risk mitigation. Manage contracts with staffing agencies and workforce suppliers, including service quality, performance oversight, and issue resolution in partnership with Talent Acquisition. Reporting on contingent workforce headcount, spend, tenure, compliance status, and overall workforce mix. Immigration &amp; Global Mobility Serve as the HR operations point of contact for immigration and work authorization programs, partnering closely with external immigration counsel and internal teams. Support visa and work authorization processes (e.g., H-1B, TN, O-1, L-1, E-3, and other country-specific visas and permits), ensuring accurate documentation and timely case coordination. Advise Talent Acquisition Partners, HR Business Partners and leaders on immigration considerations related to hiring, role changes, and workforce planning. Monitor changes in U.S. and global immigration and mobility regulations and policies, proactively assessing impact and recommending mitigation strategies when needed. Provide operational oversight of employee mobility and relocation activities across both U.S. domestic and international (ex-U.S.) moves, in partnership with relocation vendors, immigration counsel, and internal stakeholders. &nbsp;Global Workforce Partner (PEO/EOR) Management Own operational relationships with Global Workforce Partners (PEOs/EORs) supporting international employees. Ensure consistent and compliant employee lifecycle management for PEO-employed staff, including onboarding, offboarding, employment changes, and documentation. Oversee PTO tracking, leave administration, and local statutory benefits in partnership with PEO providers. Coordinate country-specific employment updates, including changes to compensation practices, benefits, policies, and statutory requirements. Ensure global workforce practices balance local compliance, internal consistency, and a positive employee experience across countries. Maintain accurate workforce data and reporting aligned between internal HR systems and PEO records. &nbsp;HR Systems, Data &amp; Reporting Serve as the functional owner for HR systems (e.g., HRIS, ATS, Benefits), ensuring configuration supports compliance, reporting accuracy, and scalability. Lead system enhancements, integrations, and process improvements to enable automation and executive-ready reporting. Deliver dashboards and insights on headcount, attrition, workforce mix, and compliance tracking, Qualifications Bachelor’s degree in Human Resources, Business, Life Sciences, or a related field; advanced degree or HR certification (SHRM-SCP, SPHR) preferred. 8–12+ years of progressive HR experience, including significant experience in HR Operations within a biotech, pharmaceutical, or life-sciences environment. Demonstrated experience leading and developing teams, including direct management of employees and contractors. Experience supporting regulated, high-growth organizations and commercialization-ready operations. Working knowledge of contingent workforce management, immigration processes, and global employment models (PEO/EOR). Hands-on experience with HR systems, workforce data governance, and reporting. Proven ability to partner cross-functionally and operate effectively in fast-paced, evolving environments. This role may be performed remotely within the United States, with a strong preference for candidates based in or willing to work in a hybrid capacity in San Diego, CA. Gossamer Bio is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants and complies with all applicable national, state and local laws governing nondiscrimination in employment. &nbsp; &nbsp;The expected salary range for this position is listed below. Actual pay will be determined based on experience, qualifications, and other job-related factors permitted by law. &nbsp;This position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. This position also qualifies for the benefits as listed below.Gossamer Bio offers highly competitive benefit plans and programs, including medical, dental and vision insurance, 401(k) and 401(k) matching , long-term incentive plan, disability plan, vacation pay, sick time, holiday pay, and work, personal and family time off in accordance with the terms of the applicable plans. For additional general information on Company benefits, please visit https://www.gossamerbio.com/work-at-gossamerbio/Pay Range$171,000&mdash;$220,000 USDCalifornia Consumer Privacy Act (CCPA) Notice for California Residents:This notice is to notify you that personal data about you has been collected by Gossamer Bio (“Controller”), which is located at 3115 Merryfield Row, Suite 120, San Diego CA 92121 and can be contacted by emailing privacy@gossamerbio.com, because Controller wishes to evaluate your candidacy for employment at Controller. Your personal data was either obtained from publicly available sources (e.g. LinkedIn) or provided to Controller by someone who referred you for potential employment. &nbsp;Controller’s Privacy team can be contacted at privacy@gossamerbio.com. &nbsp;Your personal data will be processed for the purposes of managing Controller’s recruitment related activities, which include setting up and conducting interviews and tests for applicants, evaluating and assessing the results thereto, and as is otherwise needed in the recruitment and hiring processes. &nbsp;Such processing is legally permissible under Art. 6(1)(f) of Regulation (EU) 2016/679 (General Data Protection Regulation) and the California Consumer Privacy Act (CCPA) as necessary for the purposes of the legitimate interests pursued by the Controller, which are the solicitation, evaluation, and selection of applicants for employment. Your personal data has been shared with Greenhouse Software, Inc., a cloud services provider located in the United States of America and engaged by Controller to help manage its recruitment and hiring process on Controller’s behalf. &nbsp;&nbsp; Your personal data will be retained by Controller as long as Controller determines it is necessary to evaluate your application for employment. &nbsp;Under the GDPR and CCPA, you have the right to request access to your personal data, to request that your personal data be rectified or erased, and to request that processing of your personal data be restricted. &nbsp;You also have to right to data portability. &nbsp;In addition, you may lodge a complaint with a supervisory authority.

Associate Director/Director, HR Operations

SUMMARY: The Senior Director, Commercial Supply / Project Lead will provide strategic and operational leadership for commercial supply activities across the small molecule and drug–device combination product portfolio. The role requires deep expertise in supply chain readiness, and regulatory expectations to support global commercialization. RESPONSIBILITIES Serve as Commercial Supply Chain Lead, driving end-to-end planning and execution of commercial manufacturing, packaging, labeling, and distribution strategies for small molecule and combination products. Develop supply strategy to maximize supply efficiency, minimize waste while identifying risk and risk mitigation plans. Develop SOPs and work instructions required to manage supply. Govern supply and operations planning (S&amp;OP) process for end-to end supply chain, including device components. Lead supply chain’s PAI readiness and product launch activities. Lead launch readiness planning and execution, ensuring supply continuity. Responsible for Commercial end-to-end supply chain activities for license to operate. Collaborate closely with internal partners (Regulatory, Quality, Commercial, and Supply Chain) and external CMOs/CDMOs. Oversee relationships and activities with third parties (packager, carrier). Manage supply chain setup for global commercial launch, including demand forecasting, inventory management, and distribution logistics. Support lifecycle management activities, including new presentations, line extensions, and post-approval manufacturing changes. Ensure compliance with GMP, ICH, and regional regulatory requirements (FDA, EMA, etc.). Provide technical and strategic input during regulatory submissions and inspections. Identify hiring strategy to build the commercial supply chain team; lead candidate identification, selection and onboarding. Drive continuous improvement and operational excellence initiatives across commercial manufacturing networks. &nbsp; JOB QUALIFICATIONS BS/BA in Supply Chain, Science or Economics/Finance with 15 years’ experience. Excellent understanding of the Pharma industry &amp; In-Country supply chain needs strongly preferred (orphan drugs experience a plus). 10+ years’ supply chain management experience within Pharma or other Lifesciences manufacturing environments. Ability to set up mission/vision/strategy for Commercial Supply Chain and translate into key strategic drivers. Experienced in implementing and maintaining serialization systems to ensure compliance with current and future regulations. Expertise with MRP/ERP system implementation and integration Strong understanding of supply chain operations and GMP manufacturing. Prior experience supporting global commercialization Experience managing external partners (CDMOs/CMOs) and complex global supply networks. Excellent leadership, communication, and cross-functional collaboration skills. Ability to thrive in a fast-paced, matrixed biotech environment. Positions can be based in San Diego, CA (Hybrid) or Remote. Up to 20% Domestic and International Travel. Gossamer Bio is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants and complies with all applicable national, state and local laws governing nondiscrimination in employment. &nbsp;The expected salary range for this position is listed below. Actual pay will be determined based on experience, qualifications, and other job-related factors permitted by law. &nbsp;This position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. This position also qualifies for the benefits as listed below.Gossamer Bio offers highly competitive benefit plans and programs, including medical, dental and vision insurance, 401(k) and 401(k) matching , long-term incentive plan, disability plan, vacation pay, sick time, holiday pay, and work, personal and family time off in accordance with the terms of the applicable plans. For additional general information on Company benefits, please visit https://www.gossamerbio.com/work-at-gossamerbio/Pay Range$227,000&mdash;$250,000 USDCalifornia Consumer Privacy Act (CCPA) Notice for California Residents:This notice is to notify you that personal data about you has been collected by Gossamer Bio (“Controller”), which is located at 3115 Merryfield Row, Suite 120, San Diego CA 92121 and can be contacted by emailing privacy@gossamerbio.com, because Controller wishes to evaluate your candidacy for employment at Controller. Your personal data was either obtained from publicly available sources (e.g. LinkedIn) or provided to Controller by someone who referred you for potential employment. &nbsp;Controller’s Privacy team can be contacted at privacy@gossamerbio.com. &nbsp;Your personal data will be processed for the purposes of managing Controller’s recruitment related activities, which include setting up and conducting interviews and tests for applicants, evaluating and assessing the results thereto, and as is otherwise needed in the recruitment and hiring processes. &nbsp;Such processing is legally permissible under Art. 6(1)(f) of Regulation (EU) 2016/679 (General Data Protection Regulation) and the California Consumer Privacy Act (CCPA) as necessary for the purposes of the legitimate interests pursued by the Controller, which are the solicitation, evaluation, and selection of applicants for employment. Your personal data has been shared with Greenhouse Software, Inc., a cloud services provider located in the United States of America and engaged by Controller to help manage its recruitment and hiring process on Controller’s behalf. &nbsp;&nbsp; Your personal data will be retained by Controller as long as Controller determines it is necessary to evaluate your application for employment. &nbsp;Under the GDPR and CCPA, you have the right to request access to your personal data, to request that your personal data be rectified or erased, and to request that processing of your personal data be restricted. &nbsp;You also have to right to data portability. &nbsp;In addition, you may lodge a complaint with a supervisory authority.

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