Alumis, established in 2005, is a leading innovator in sustainable energy solutions. The company's cutting-edge technologies in solar power and energy storage have revolutionized the renewable energy sector, driving the transition towards a cleaner and more efficient future. Alumis continues to push boundaries with its comprehensive range of eco-friendly products and services, making significant strides in combating climate change and promoting environmental sustainability on a global scale.

Manager, Supply Chain

Scientist, DPMK

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.&nbsp;Alumis Inc is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer – our goal is to fundamentally change the outcomes for these patients. We are seeking an experienced and motivated Director, CMC Program Management. In this highly visible, exciting role, you will guide our CMC Tech Ops team in partnership with the molecule development team and cross-functional team leads, providing exceptional program management for our lead molecule, currently in Phase 3. This position will report to the Head of Program and Portfolio Management (PPM). RESPONSIBILITIES Actively partner with CMC team leads, providing leadership and guidance for team and to team members Provide Project Management support by coordinating and aligning teams and associated workstreams, and managing their activities. This includes meeting facilitation, tracking of action items and team deliverables, to execute on program’s strategic plan and strategic objectives. CMC Teams this position will support include but are not limited to CMC operations for our lead molecule, strategic CMC core team across portfolio, and Module 3 team for NDA filing Partner with other PMs (Ex. Molecule PMs (supporting Project Team, Clinical Development teams, etc), Medical Affairs PM, Commercial PM) to ensure seamless PPM support across molecules Act as a vendor liaison, providing contract, requisition processing, and invoice management support, as well as following up with vendor on project updates and status reports, to ensure timely and quality deliverables, including tracking of reports for Module 3 Ensure effective communication within functional team and stakeholders to support good decision-making in fast-paced small company environment Proactively identify, analyze and communicate decision points and project risks, including tradeoff and scenario analyses (including timelines, costs, and risks), framing options within broader molecule or portfolio context Identify needs and propose solutions to project and portfolio tools, systems and practices to support the growth and evolution of PPM’s capabilities As needed, provide Business Manager support to Head of Technical Operations – potential responsibilities include project managing quarterly functional meetings, serving and functional rep for enterprise processes (ex Training system) and facilitating team culture within function As needed, support other business priorities within PPM, including but not limited to potential assignments in research, development, clinical, medical affairs, or commercial project management THE IDEAL CANDIDATE Minimum 12 years industry experience, with at least 5 years of drug development project management (e.g. research, clinical, CMC, commercial, medical affairs), including CMC project management experience Experience with filing and launch for small molecules Highly skilled in communication, stakeholder management, and influencing without authority, where you are able to effectively interact with, and facilitate complex conversations across the organization Excellent critical thinking, verbal and written communication skills, with ability to simplify and integrate multiple cross-functional perspectives and inputs for team Agile and flexible: Able to step in, assess situations, and help team to make sound decisions in alignment with program strategy Strong organizational skills with critical attention to detail and ability to track to numerous deliverables Broad scientific and business acumen in the biotech or pharmaceutical industry, including a strong understanding of cross-functional dependencies Proficient with Microsoft Office Suite, as well as project management software such as MS Project and Smartsheets EDUCATION B.A. or BSc. with MSc., MBA or Ph.D. a plus Project Management Professional (PMP) or other PM certification a plus Alumis Values Elevate Challenge Nurture &nbsp; This position is located in South San Francisco, CA. At this time we are not considering remote applicants. Alumis Inc. is an equal opportunity employer. &nbsp;

Director, CMC Program Management (Contractor)

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.&nbsp;We are seeking an Associate Director of Biostatistics to provide statistical expertise and operational support across a variety of clinical activities with a focus on supporting early-stage and late-stage clinical programs. &nbsp;This role will serve as lead study statistician, collaborating with cross-functional teams to support clinical development and data-driven decision-making. The Associate Director will contribute hands-on to key deliverables, manage CROs, and provide guidance to junior team members.&nbsp; &nbsp; Essential Responsibilities: Contribute to the statistical design and analysis of early and late phase clinical studies.&nbsp; Apply advanced statistical methods and data visualization skills to clinical trial data summaries and interpretations such as integrated safety and efficacy analyses for regulatory submissions.&nbsp; Serve as the biostatistics representative on cross-functional teams, ensuring alignment of statistical approaches with study and program objectives.&nbsp; Provide input on study design, endpoint selection, and sample size planning.&nbsp; Draft statistical analysis plans (SAPs) and support interpretation of results.&nbsp; Ensure the quality and accuracy of statistical deliverables by independently generating the statistical deliverables and/or independently reviewing and validating the statistical deliverables generated by either CRO or internal statistical programming team.&nbsp; Manage CROs and mentor junior staff or contractors as appropriate.&nbsp; The Ideal Candidate: Education:&nbsp; Ph.D. in Biostatistics with 6+ years of relevant industry experience, or Master’s with 8+ years. Experience:&nbsp; Significant experience serving as a study statistician on global Phase III clinical trials, ideally in immunology or immune-mediated diseases. Demonstrated track record of supporting regulatory submissions (NDA/BLA/MAA), including integrated safety/efficacy analyses. Hands-on experience working in a biotechnology or pharmaceutical company environment (not only CRO, Site, or Academic). Proven ability to manage CROs and statistical programming teams in a sponsor setting. Strong foundation in clinical trial design, statistical analysis, and regulatory guidelines. Proficiency in statistical programming (SAS and R). Experience in publication work and/or analysis of real-world data preferred.&nbsp; Demonstrated ability to manage multiple priorities and work cross-functionally.&nbsp; Experience with both early-stage and late-phase clinical trials.&nbsp; Skills:&nbsp; Strong analytical thinking and attention to detail.&nbsp; Excellent verbal and written communication skills.&nbsp; Ability to work independently in a fast-paced, regulated environment.&nbsp; Ability to manage deliverables with competing priorities and influence others effectively.&nbsp; Strong organizational skills, with the ability to manage workflows and activities to meet department timelines.&nbsp; Collaborative mindset and ability to influence without authority.&nbsp; &nbsp; The salary range for this position is $190,000 USD to $230,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices. This position is located in South San Francisco, CA, with an expectation to be onsite Tuesday through Thursday. While we prefer local candidates, remote applicants based in the Pacific Time Zone will be considered on a case-by-case basis. Alumis Inc. is an equal opportunity employer. Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program. &nbsp; Other benefits include: Health insurance premiums paid at 90% for employee, 80% for dependents Free access to Genentech Bus &amp; Ferry Share program $100 monthly cell phone stipend Unlimited PTO for Exempt employees Free onsite gym and a kitchen stocked with yummy snacks and drinks! We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to&nbsp;elevate,&nbsp;challenge&nbsp;and&nbsp;nurture&nbsp;one another along the way. &nbsp; &nbsp;

Associate Director, Biostatistics

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.&nbsp;As a Director of Data Management, you will play a critical role in ensuring the integrity, quality, and readiness of clinical data that will drive key decisions across our development programs—including ongoing studies in lupus and beyond.&nbsp; In this role, you will lead data management activities across multiple studies, partnering closely with cross-functional teams to ensure our data not only meets regulatory standards but also tells a clear and actionable story. From CRF design and database development to data transfer agreements and database lock, you will guide critical processes that support the advancement of therapies with the potential to change patients’ lives.&nbsp; This role reports to the Vice President of Data Management and offers a unique opportunity to contribute to a high-performing team at the forefront of immunology drug development.&nbsp; &nbsp; Responsibilities:&nbsp; Lead and deliver: May serve as the Data Management Program Lead; Will serve as Study Lead across multiple clinical trials, owning data management from study start-up through database lock and archival.&nbsp; Team leadership and mentoring: Manage and develop data management study leads and supporting team members; foster a high-performance, collaborative culture.&nbsp; Vendor oversight: Establish and manage relationships with contract research organizations and data management vendors; oversee scope, timelines, performance, and compliance.&nbsp; Standards and systems: Drive case report form design and clinical database builds; oversee integrations between electronic data capture systems and interactive response technologies (electronic data capture and interactive response technology/interactive voice response systems).&nbsp; Testing and readiness: Lead user acceptance testing by creating test plans and scripts and executing test cycles to ensure system readiness.&nbsp; Documentation: Author and review core data management documentation, including case report form specifications and annotations, case report form completion guidelines, Data Management Plans, Data Validation Specifications, and Data Transfer Specifications and agreements; maintain inspection-ready files.&nbsp; Data quality: Execute and oversee validation checks and ongoing reviews according to the Clinical Data Review Plan; manage routine data transfers and reconcile external data to ensure accuracy and consistency.&nbsp; Cross-functional collaboration: Represent Data Management with Clinical Operations, Biostatistics and Statistical Programming, Regulatory Affairs, and Medical teams; review clinical protocols, Statistical Analysis Plans, and mock tables, figures, and listings; support blinded data reviews prior to database lock.&nbsp; Metrics and reporting: Track and communicate data quality and cleaning metrics, including query trends and source data verification progress, to study teams and stakeholders.&nbsp; Process improvement: Lead initiatives that enhance data quality, efficiency, and scalability through improved processes, tooling, and automation.&nbsp; RFP participation: Contribute to vendor requests for proposals, technical evaluations, and contract and budget discussions.&nbsp; &nbsp; Qualifications:&nbsp; 12+ years of relevant experience and has earned a BS or equivalent degree; MS or MBA a plus&nbsp; Experience running Ph I-IV clinical trials, both in-house and through CRO partners&nbsp; Strong knowledge and experience in EDC and other key technologies (e.g., IXRS, data visualization)&nbsp;&nbsp; Proficiency in CDISC standards (CDASH, SDTM, ADaM)&nbsp; Experience with SAS, SQL and/or other clinical programming tools&nbsp; Proficiency in clinical research regulations and guidance, including FDA CFR and ICH GCP&nbsp;&nbsp; Depth of experience across all aspects of DM, including but not limited to: CRF and database development, data quality assurance and analytics, data transfer management, vendor management, DM study documentation and inspection readiness.&nbsp;&nbsp; Strong understanding of the application of MedDRA and WHO Drug clinical data coding classification systems&nbsp; Strong interpersonal, organizational, and communication (oral and written) skills&nbsp; Demonstrated ability to cultivate strong working relationships with internal and external colleagues.&nbsp; Logical thinking, attention to detail and accuracy, strong organizational skills, and problem-solving abilities&nbsp; Ability to prioritize and to adapt quickly to changing business conditions with a “can-do” attitude&nbsp; Capable of proactively identifying project challenges and risks and proposing appropriate and strategic solutions to issues.&nbsp; Willing to travel if required&nbsp;&nbsp; &nbsp; Alumis Values&nbsp;• We Elevate&nbsp;• We Challenge&nbsp;• We Nurture&nbsp; &nbsp; This position is located in South San Francisco, CA. At this time, we are not considering remote applicants.&nbsp;&nbsp; The salary range for this position is $190,000 USD to $235,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.&nbsp; &nbsp; Alumis Inc. is an equal opportunity employer. If you are hired, we will require you to prove that you have received the primary series of an FDA-approved or authorized COVID -19 vaccine and at least one booster or have a valid religious or medical reason not to be vaccinated.&nbsp; &nbsp;

Director, Data Management

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.&nbsp;Responsibilities: Support late-stage and launch readiness strategy for ESK-001 in dermatology, serving as the cross-functional medical lead for executional initiatives. Translate clinical data into high-impact medical education, scientific communications, and evidence-generation strategy. Develop and execute comprehensive medical education plans (CME and non-CME) aligned to strategic imperatives and HCP education needs. Drive execution of medical congress activities, including abstract planning, insight capture, on-site engagement, and coordination with field teams. Serve as the day-to-day medical lead for KEE (key external expert) engagement planning, field medical resource development, and internal field alignment. Partner with MSL leadership on field strategy, training, insight management, and field-facing content development. Support the medical strategy and execution of scientific publications in collaboration with Scientific Communications, including data communication and external authorship management. Plan and execute scientific advisory boards across HCP segments (Tier 1, Emerging, APPs) to gather insights and refine positioning. Collaborate cross-functionally with Clinical Development, Commercial, Regulatory, Legal, and Program Management to ensure alignment across data, messaging, and launch milestones. Represent Alumis at major dermatology congresses and serve as a medical voice supporting the strategic goals of the ESK-001 program. Experience, Education, and Specialized Knowledge and Skills: Must thrive in a fast-paced, innovative environment while remaining proactive, resourceful, and adaptable. Deep understanding of the dermatology therapeutic landscape, especially immunology and psoriasis. Exceptional ability to translate clinical and mechanistic data into medical strategy and execution plans. Proven experience leading cross-functional initiatives in support of late-stage development or product launch. Strong interpersonal and relationship-building skills with both internal stakeholders and external thought leaders. Experience delivering scientific insights and HCP-facing content in a clear, concise, and strategic manner. &nbsp; Basic Qualifications: Advanced clinical or scientific degree (MD, DO, PhD, PharmD, NP/PA) required. Minimum of 5 years combined experience in the pharmaceutical industry, clinical practice, or academic setting focused on dermatology or immunology. &nbsp;Preferred Qualifications: Demonstrated success developing and executing medical strategy for late-stage programs or product launch. Experience in designing and executing medical education (CME and non-CME), congress planning, and KEE engagement. Ability to manage multiple complex initiatives with strategic clarity and operational precision. Seen as a credible, collaborative scientific leader by internal and external stakeholders. Highly strategic thinker with strong execution capabilities and the ability to translate ambiguity into clear action. Ability to travel and engage with HCPs and KOLs across the US and internationally. Embodies Alumis values and commitment to transforming care for patients with immune-mediated diseases. Title commensurate with education, experience, and qualifications. The salary range for this position is $210,000-250,000 This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices. This position is located in South San Francisco, CA, with an expectation to be onsite Tuesday through Thursday. While we prefer local candidates, remote applicants will be considered. Alumis Inc. is an equal opportunity employer. Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program. &nbsp; Other benefits include: Health insurance premiums paid at 90% for employee, 80% for dependents Free access to Genentech Bus &amp; Ferry Share program $100 monthly cell phone stipend Unlimited PTO for Exempt employees Free onsite gym and a kitchen stocked with yummy snacks and drinks! &nbsp; We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to&nbsp;elevate,&nbsp;challenge&nbsp;and&nbsp;nurture&nbsp;one another along the way.

Director, Medical Affairs

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.&nbsp;Alumis is hiring a Clinical Quality Assurance Director, reporting to the SVP, of Quality and Regulatory. The role will work closely with the Quality, Development, and Study Execution Teams to provide Clinical Quality support for all ongoing clinical studies. This involves working closely with Clinical Operations, Clinical Development, Clinical Supply Chain, Medical Affairs, Regulatory, Legal, and other teams across Alumis. The Clinical QA Director is responsible to ensure quality is embedded throughout the lifecycle of all the ongoing clinical programs through oversight, assessment and monitoring, risk assessment tools and risk mitigations. The Director will be responsible to establish Key Performance Indicators and Metrics to trend and track on the health of the clinical trials.&nbsp; The role is responsible to provide the operational quality support and guidance for the development teams and support the SVP of Quality and Regulatory in building the Alumis Quality organization strategy and vision. This position requires expertise in Good Clinical Practices and relevant US and EU regulations. The successful candidate will drive, promote, and embed a culture of ethics, integrity, and proactive quality management.&nbsp; The candidate will provide guidance and leadership to ensure that the quality function maintains the standards expected by global regulatory authorities.&nbsp; ESSENTIAL DUTIES &amp; RESPONSIBILITIES Establish, maintain and enhance GCP QA programs, policies, and procedures. Ensure ongoing clinical programs are in compliance with applicable health authority regulations and guidelines. Act as the primary GCP QA subject matter expert and point of contact for all GCP/CSV related matters and issues for the assigned program, project or study. Establish the study specific audit plan ensuring successful execution and audit findings close out including CAPA management and oversight. Establish and manage the Quality Risk Management program. Represent Quality on project teams, Health Authority Inspections, service providers and CROs operational meetings, and QA to QA meetings. Support Quality Review meetings content and material. Prepare and manage Quality KPI and metrics. Provide quality oversight and review of key Clinical and IND/NDA enabling documents. Perform reviews of clinical trial documentation for data integrity and compliance with Good Clinical Practice guidance and regulations. Conduct root cause analysis for recurring issues. Partner in implementation of inspection readiness plans and activities. Act as the primary liaison with Development and Compliance team in execution of inspection and audit readiness plans including for internal/external and business partners audits. Support clinical service provider selection and qualification activities and develop periodic compliance/metric reports. EDUCATION &amp; EXPERIENCE Bachelors or advanced degree in Biology, Chemistry, or related field. Minimum 10 years of Clinical Quality Assurance experience. Strong understanding of small molecule products with direct experience in solid oral dosage forms. KNOWLEDGE/ SKILLS/ ABILITIES Extensive knowledge of FDA regulations and practices, ICH guidance, and strong knowledge of global health authority regulations and practices. Hands-on experience in drug life cycle management. A successful track record of working with service providers and CROs. Ability to make timely and sound quality decisions when faced with complex clinical, compliance, technical and regulatory considerations. Highly skilled in the ability to work with ambiguity and complexity. Knowledge of Quality Management Systems; experience in implementing and managing quality systems in the pharmaceutical industry. Excellent verbal and written communication skills. Collaborative, analytical and interpretative skills. Ability to work with minimal supervision, to set priorities to meet timelines, to motivate and influence others. Prior management experience is required. Previous experience in successfully leading assigned activities within cross-functional teams. Some travel required. The salary range for this position is $190,000 USD to $240,000&nbsp; USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices. This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday. Lab personnel, however, are generally onsite 4-5 days/week. &nbsp;At this time we are not considering remote applicants. Alumis Inc. is an equal opportunity employer. Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program. &nbsp; Other benefits include: Health insurance premiums paid at 90% for employee, 80% for dependents Free access to Genentech Bus &amp; Ferry Share program $100 monthly cell phone stipend Unlimited PTO for Exempt employees Free onsite gym and a kitchen stocked with yummy snacks and drinks! We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to&nbsp;elevate,&nbsp;challenge&nbsp;and&nbsp;nurture&nbsp;one another along the way.

Director of Clinical Quality Assurance

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.&nbsp;&nbsp; &nbsp; We are seeking an experienced medical professional to serve as a Medical Director, Rheumatology, reporting to the Vice President of Clinical Development, Rheumatology. The successful individual will play a pivotal role in advancing our clinical programs from Phase 2 through regulatory approval. You will contribute to the strategic planning, execution, and management of the SLE program which currently consists of a Phase 2b study (the LUMUS Trial) designed to be the first of two pivotal studies with ESK-001 in SLE. ESK-001 is a highly selective TYK-2 inhibitor which has the potential to be a best-in-class oral treatment for SLE. Collaborating closely with cross-functional teams, this person will contribute to the scientific and medical vision, and provide leadership in the development of innovative therapies to address unmet medical needs in SLE and related inflammatory conditions. &nbsp; RESPONSIBILITIES: · Serve as the Sponsor medical monitor for the LUMUS trial and collaborate with CRO to provide monitoring oversight; · Review and follow all SAEs; · Participate in in-stream data reviews; · Interact with PIs and site staff (e.g.: by raising and responding to queries); · Draft key study documents (e.g.: responses to Regulatory requests for information); · Work on the cross-functional Study Execution Team for LUMUS and broadly across Rheumatology Clinical Development programs at Alumis; · Contribute to the design and development of clinical studies as well as other cross-functional initiatives; · Has opportunities for external engagement (e.g.: participation in Investigator Meetings, external Data Monitoring Committee reviews, etc…); · Maintains the highest levels of integrity and ethical standards for scientific inquiry in drug development. QUALIFICATIONS AND SKILLS REQUIRED: · Licensed physician (required); · Board certification in rheumatology or related field (desired); · Industry experience in pharmacovigilance or clinical development (helpful); · Ability to interact effectively in a cross-functional setting; · Strong interpersonal and communications skills (written and verbal) to effectively address all levels within an organization; · Ability to assess, understand, and communicate continuously expanding medical and scientific information; · Ability to work across diverse teams in a matrixed organizational structure, both as a leader and as part of a cross-functional team; · Approaches deliverables in an organized manner with attention to detail and is able to meet timelines in a fast-paced environment; · Able to work productively with a high level of independence. The salary range for this position is $285,000 USD to $325,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices. This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday. Open to remote applicants with requirement to be onsite once a month. Alumis Inc. is an equal opportunity employer. Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program. &nbsp; Other benefits include: Health insurance premiums paid at 90% for employee, 80% for dependents Free access to Genentech Bus &amp; Ferry Share program $100 monthly cell phone stipend Unlimited PTO for Exempt employees Free onsite gym and a kitchen stocked with yummy snacks and drinks! We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to&nbsp;elevate,&nbsp;challenge&nbsp;and&nbsp;nurture&nbsp;one another along the way.

Medical Director, Rheumatology

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.&nbsp;&nbsp; We are seeking an experienced Senior Clinical Development Medical Director who will be involved across the full scope of dermatology and autoimmune clinical drug development activities from discovery research through first in human, POC, and Phase 3 studies. The role will include leadership of one or more studies within the portfolio and will work closely with all members of the cross-functional asset team, to apply full clinical knowledge to successfully advance clinical programs as well as the overall asset strategy. &nbsp; Responsibilities Broadly represent the interests of Alumis as a senior leader and spokesperson for Clinical Development within the fields of Dermatology and Immunology Provide leadership in the management and oversight of the global ESK-001 Phase 3 program in plaque psoriasis, leading one or more studies Effectively contribute to cross-functional teams within Research, Biomarkers, Medical Affairs, Commercial, and Study Team as an expert within the Dermatology therapeutic area and broadly across immune mediated inflammatory diseases Support the clinical Science function contributing to the design and development of novel clinical studies and cross-functional initiatives Provide strategic support and implement clinical strategies across early and late stage clinical development programs Coach, manage, inspire, and support team members to achieve business goals by leveraging an entrepreneurial and collaborative mindset Maintain the highest levels of integrity within development and standards for scientific inquiry in drug development Collaborate with CRO to provide medical monitoring oversight for the Phase 3 program Support the planning and execution of publication plan and data generation, as well as submission activities &nbsp; Qualifications: MD or ex-US equivalent with board certification or eligibility in Dermatology or in a related immunology disease area with &gt; 5 years of drug development experience (data review, CRF query handling, medical monitoring, writing papers) Notable communication skills with credibility to interface with Key Opinion Leaders, external health organizations and regulators within Dermatology Ability to interact effectively in a cross-functional setting Strong interpersonal, influencing, presentation, and communications skills (written and verbal) to effectively address all levels within an organization Ability to assess, understand, and communicate continuously expanding medical and scientific information, as well as knowledge of commercial dynamics impacting drug development Strong business acumen and ability to collaborate with cross-functional partners to achieve enterprise goals Effective negotiation skills that enable the candidate to influence without authority Proven professional track record of strategic, organizational, and executional skills to support project planning across multiple activities, with the ability to anticipate and prioritize one’s workload across multiple projects of equal importance Ability to work across diverse teams in a matrixed organizational structure, both as a leader and as part of a cross-functional team Approaches deliverables in an organized manner with attention to detail and is able to meet timelines in a fast-paced environment Able to work autonomously and with a high level of independence &nbsp; The salary range for this position is $325,000 USD to $358,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices. This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday. Open to remote applicants with requirement to be onsite once a month. Alumis Inc. is an equal opportunity employer. Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program. &nbsp; Other benefits include: Health insurance premiums paid at 90% for employee, 80% for dependents Free access to Genentech Bus &amp; Ferry Share program $100 monthly cell phone stipend Unlimited PTO for Exempt employees Free onsite gym and a kitchen stocked with yummy snacks and drinks! We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to&nbsp;elevate,&nbsp;challenge&nbsp;and&nbsp;nurture&nbsp;one another along the way.

Senior Clinical Development (Medical Director), Dermatology

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.&nbsp;Sr. Director, Quality Intelligence and Systems Alumis is hiring a forward-thinking Senior Director of Quality Intelligence and Systems reporting to the Senior Vice President of Quality and Regulatory.&nbsp; The Sr. Director is responsible to optimize quality systems and its management to fulfill the purpose of detection, maintenance, and correction of the underlying quality process of interest (e.g., documentation, training/qualification, deviation, CAPA, change control, supplier management, product complaints). In addition, this role interprets, integrates, and applies compliance signals to ensure compliance adherence that is informed by the latest quality regulations, guidance, or expectations. This position requires extensive expertise in the GxPs and relevant regulations. The successful candidate drives, promotes, and embeds a culture of ethics, integrity, and proactive quality management.&nbsp; The candidate provides support to ensure that the quality function maintains the standards expected by the health authorities and facilitates “Right-First-Time” and phase appropriate decisions through risk and knowledge management processes.&nbsp; ESSENTIAL DUTIES &amp; RESPONSIBILITIES Partner closely with the SVP, Quality and Regulatory to drive execution of strategic priorities and departmental planning. Oversee and manage the Quality Systems group, including but not limited to document control, training, quality supplier management deviation, CAPA, and change control, maintaining content and execution ownership with the functional areas. Oversee the global Quality Systems strategy, integrating data, insights, and compliance signals to enable proactive, risk-based decision-making. Lead and align cross-functional initiatives that advance quality system maturity, inspection readiness, and operational excellence. Act as a strategic liaison between the Quality Systems function and the business. Lead Quality Governance processes (QSMR, SOGO, ITQuality..etc.)&nbsp; that elevate enterprise visibility, foster a right-first-time mindset, and support a high-performing quality culture. Lead development and tracking of Quality KPIs to measure performance and support continuous improvement. Act as the “Chief of Staff” for the Quality team. Facilitate the operating rhythm of the Quality leadership team, ensuring alignment and follow-through on key decisions. Develop and maintain a comprehensive knowledge of compliance signals that inform strategic quality decisions and initiatives. Bridge quality insights into actionable strategies to ensure the company remains at the forefront of industry compliance and quality standards. Drives continuous improvement initiatives based on quality trends and intelligence. Develop and implement quality strategies and systems that integrate quality intelligence to enhance compliance and operational efficiency. Collaborates with cross-functional teams to ensure alignment of quality objectives and acts as a liaison with suppliers to address quality systems issues. Author/review or approve appropriate quality documents including SOPs, quality systems records, and health authority responses.&nbsp; Promote a culture of proactive quality management and health authority compliance ensuring quality mindset and quality excellence approach throughout the organization. Uses data to recognize trends, shape strategy, and inform activities using dashboards and other communication vehicles. EDUCATION &amp; EXPERIENCE Bachelor’s degree, advanced degree preferred, in a scientific discipline, communication, business, or training with a minimum of 12 years of industry experience, including relevant combination of education, experience, or training in GxP, quality assurance, quality intelligence, or Life Sciences. Five (5) plus years of management experience leading teams and influencing stakeholders internal and external. Experience in implementing and managing electronic quality management systems (eQMS), including document management, and learning management systems. Experience interacting with health authorities through supporting inspection with on demand evidence fulfillment or interaction with the investigator, and/or writing responses to findings/observation. Familiarity with the Quality Management Maturity Model. Experience with an emerging virtual company. KNOWLEDGE/ SKILLS/ ABILITIES Demonstrates strong knowledge of global GxP expectations, regulations, and quality trends across the product development lifecycle – bench to bedside. Demonstrates the ability to organize, sequence tasks per priority, delegate, thrive in a fast-paced, deadline driven environment, and communicate meaningful expectations. Develops key quality metrics, including quality system, process, and people metrics, that provides insights and foresights in identifying and addressing quality systems or product concerns or opportunities. Exhibits strong interpersonal skills, with experience in leading high-performance team and cross functional projects including a successful track record working with senior management and other key stakeholders. Establishes effective escalation paths that communicates a current context and then a proactive, evidence-based solution while calibrating management and supplier awareness and action. Demonstrates a goal orientation with a completion mindset that incorporates the ability to troubleshoot, resolve problems, and learn from and then share the learning with others. Advocates continuous improvement to quality processes, well-trained workforce, streamlined business processes, and appropriately structured quality operations. Demonstrates a self-organizing orientation that leverages minimal supervision, constructs priorities and deadlines based on the needs of the business and quality requirements and motivates and influences others.&nbsp; Recruits, develops, trains, mentors, coaches, and counsels team members for success and high performance. Be willing to travel 5% of the time. ALUMIS VALUES We Elevate We Challenge We Nurture This position is located in South San Francisco, CA. At this time, we are not considering remote applicants. Alumis Inc. is an equal opportunity employer. If you are hired, we will require you to prove that you have received the primary series of an FDA-approved or authorized COVID -19 vaccine and at least one booster or have a valid religious or medical reason not to be vaccinated. The salary range for this position is $236,000-$295,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.&nbsp;&nbsp; Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program. &nbsp; Other benefits include: Health insurance premiums paid at 90% for employee, 80% for dependents Free access to Genentech Bus &amp; Ferry Share program $100 monthly cell phone stipend Unlimited PTO for Exempt employees Free onsite gym and a kitchen stocked with yummy snacks and drinks! We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to&nbsp;elevate,&nbsp;challenge&nbsp;and&nbsp;nurture&nbsp;one another along the way. *Lab personnel are generally onsite 4-5 days/week. &nbsp; &nbsp; &nbsp;

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