Executive Director, Business & Digital Platforms Lead

Company Overview: Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease.

At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities.  Learn more https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.  Role Summary: The Executive Director, Business & Digital Platforms Lead at Dyne is a strategic leader and trusted advisor who will help architect Dyne’s business systems and associated processes across R&D, G&A, and Technical Operations with a strong focus on Commercial and Medical. This role is beyond systems - it’s about leading and shaping how Dyne connects with patients and providers, how we deliver therapies efficiently, and how we scale for future launches. This individual will work in lockstep with our Business Operations teams, Commercial and Medical, and cross-functional partners across all business areas.  This individual will define and execute a roadmap that integrates cutting-edge platforms, data-driven insights, and compliant processes to support Dyne’s commercialization strategy in the US and globally.  This role is based in Waltham, MA.

Primary Responsibilities Include:   Serve as the primary technology leader and business partner across the business with a focus on Commercial and Medical functions, building strong relationships with senior leadership and stakeholders to understand business objectives, priorities, and technology and process needs and gaps.  Collaborate with Medical Affairs, Commercial Operations, Marketing, Market Access, Patient Services as well as G&A, R&D and other business functions to design and implement a technology roadmap that supports Dyne’s launch strategy and long-term growth.  Lead the delivery, support, and continuous improvement of business technology platforms (e.g., CRM, data management, omnichannel engagement, analytics), ensuring they are robust and scalable.  Align IT initiatives with business priorities, ensuring scalability for multiple product launches and global expansion.  Serve as the primary IT liaison for medical and commercial teams, translating business needs into actionable technology solutions.  Lead and manage future IT Business Partners to support business areas as Dyne grows.   Foster strong relationships with internal stakeholders and external vendors to deliver best-in-class platforms.  Enable Dyne’s Omnichannel Engagement model incorporating field learning, digital, and data insights.  Lead initiatives to implement and optimize CRM systems (e.g., Veeva Vault CRM and Patient services CRM), digital engagement tools, and analytics platforms that empower field teams and enhance customer experience.  Lead with Compliance and Trust—embedding regulatory compliance (e.g., GxP, GDPR) into every solution, safeguarding our data and maintaining Dyne’s reputation for integrity.  Oversee the lifecycle of commercial technology solutions, including requirements gathering, vendor management, implementation, and ongoing support.  Be a champion of innovation--Identifying emerging technologies that can elevate Dyne’s commercial and medical capabilities and patient engagement strategies.  Bring forward ideas that challenge the status quo and deliver measurable business impact.  Education and Skills Requirements:   Bachelor's degree required, preferably in Computer Science or Business Administration, MBA preferred  18+ years of experience as an IT leader in roles supporting commercial and medical functions, R&D and G&A functions in biotech or pharmaceutical industry  10+ years overseeing cross functional implementations, running task plans (Smartsheet preferred), setting goals and aligning dates with business needs.  AI Fluency Preferred—deploying workforce automation or using LLM enhanced processes as workforce multipliers.  Experience “building from scratch” an IT business partner team, commercial ecosystem required for launch of a rare disease product.  Deep understanding of requirements and methods to build and operate CRM platforms (preferably Veeva), patient services, omnichannel marketing, business analytics, and other digital engagement technologies.  Strong business acumen with the ability to influence senior stakeholders, motivate and lead project teams, and shape strategy.  Expertise working collaboratively--ensuring the right people are “at the table” when making key business and technology strategy decisions.  A passion for Dyne’s mission and a commitment to building systems that make a difference for patients.   Ability to articulate a commercial business technology ecosystem at all levels of our business      #LI-OnsiteMA Pay Range$241,000—$295,000 USD  The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting.

Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills. The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements.  Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

Dyne Therapeutics is a biotechnology company dedicated to advancing life-changing therapies for patients with serious muscle diseases. Leveraging its expertise in muscle biology, nucleic acid delivery, and gene therapy, Dyne is at the forefront of developing innovative treatments to address unmet medical needs and improve the lives of individuals affected by muscle disorders.