Absci is a biotechnology company that has been leading the way in advancing drug discovery and development through its innovative AI-powered platform. The company's cutting-edge technology has revolutionized the process of creating new therapies, accelerating the pace of scientific breakthroughs in the pharmaceutical industry. Absci's comprehensive approach to biopharmaceutical innovation has positioned it as a key player in driving the future of healthcare.

Senior Scientist - Translational Research - Now Hiring

Senior Research & Development Program Manager

Senior Scientist

Head of IT

People & Experience Director

Scientist - Structural Biology

Director, Alliance & Growth Strategy

Scientist II - Protein Engineering

General Interest

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.General Application: Join Absci and Redefine Possible Job Description At Absci, we are always on the lookout for extraordinary talent to help us redefine the boundaries of science and innovation. While we may not have your dream job listed today, we encourage you to submit a general application. By doing so, you’ll be the first to know when the right opportunity becomes available tomorrow. Areas of Focus Drug Discovery (In-Vitro and In-Vivo bioassays) Translational Research Protein Engineering and Structural Biology Analytical Chemistry Protein Purification Fermentation Bioinformatics Software Engineering and Data Science Machine Learning and AI Business Development Corporate (Legal, Administration, Finance, HR, etc.) Qualifications We are seeking candidates who embody Absci's core values and are eager to immerse themselves in our innovative and collaborative company culture. Successful candidates will thrive in our dynamic innovative environment and contribute as key members of project teams. If you share our vision and are excited to be part of a team that’s redefining possible, we invite you to join us. Submit your application today and become an Unlimiter at Absci!Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Head of Chemistry, Manufacturing &amp; Controls (CMC)&nbsp; Remote or Hybrid, Vancouver, WA Our Head of CMC will drive the CMC development, scale-up, cGMP manufacturing, and quality control processes to advance Absci’s internal pipeline of AI-generated antibody assets. The leader of CMC will be solely responsible for coordinating the CMC efforts in CDMOs, driving timelines of Absci’s early-phase biologics. This role requires a blend of technical expertise in chemistry and manufacturing processes, and strong internal and external communication skills. This role will also contribute to regulatory filings, requiring strong experience in technical writing and biologics regulations. Occasional travel is required.&nbsp; Responsibilities:&nbsp; Strategic Development Function as technical leader at contract development and manufacturing organizations (CDMOs) for early-phase biologics for development of both Drug Substance and Drug Product, including upstream and downstream development, gap/risk analysis, cGMP manufacturing, release, and stability.&nbsp; Provide technical guidance for cell line development, upstream process development, downstream process development, formulation development, analytical development, and drug product development.&nbsp; Review and approve controlled documents, including batch records, SOPs, protocols, and reports related to process development and characterization.&nbsp; Preparation of program/platform dashboards and presentations.&nbsp; Manage project budgets to target. Ensure that senior management/development teams are informed of important program timelines, milestones, and risks. Management of external vendors and providers Responsible for tracking commitments and communications with external vendors and providers. Keep projects in compliance with cGMP regulations.&nbsp; Coordinate activities to ensure efficient and cost-effective project completion.&nbsp; Coordinate production of commercial batches as needed.&nbsp; Cross-Functional Collaboration&nbsp; Work closely with QA to identify and evaluate deviations, CAPA and change control.&nbsp;&nbsp; Serve as a liaison between internal stakeholders and external partners, such as contract development and manufacturing organizations (CDMOs) and vendors.&nbsp; Lead and direct the work of our partner organizations and consultants. Build strong communications and relationships with partner organizations and consultants.&nbsp; Collaborate with clinical operations to ensure deliverables meet development plans. Adhere to all company policies, procedures and safety rules. Qualifications: Educational Background:&nbsp; Bachelor’s degree in a technical field such as chemistry, chemical engineering or pharmaceutical sciences. An advanced degree is preferred.&nbsp; Professional:&nbsp; Recommended to have 10 to 15&nbsp; years of industry experience in pharmaceutical development and manufacturing, with a focus on CMC; required knowledge of the biologics development process; experience interacting with key functional stakeholders such as manufacturing, QA, QC, and supply chain. Experience in planning and managing resources to deliver predetermined objectives as specified by more senior managers (Over 3 years to 6 years) Proven track record of successfully developing and setting strategy for CMC programs from development through commercialization. Flexibility to work non-traditional work hours when needed, given international operations across time zones. Ability to create and deliver presentations to influence and inform individuals across functions and levels within the organization. Ability to travel up to 10% of the time. This will include outside of the United States. How We Thrive Together: Absci’s Core Values We are one team with one finish line: You will foster strong cross-functional collaboration, ensuring smooth information flow from development to manufacturing.&nbsp; We embrace our differences: You will value and leverage the diverse backgrounds and perspectives within our team to create more robust solutions together. We deliver Results: By proactively driving project timelines and troubleshooting technical challenges, you will ensure the reliable delivery of high-quality products. We do the right thing: You will uphold the highest standards of quality and compliance, working transparently with regulatory agencies and partners to build trust and accountability. Innovate because lives depend on it: You will champion the implementation of novel manufacturing technologies and CMC strategies, supporting our mission to bring life-changing medicines to patients faster. We believe in the impossible: You will embrace experimentation, rapidly learn from setbacks, and translate those lessons into continuous CMC and process improvements. The salary range for this position is $160,000- $230,000/year. Competitive equity package applies. Pay offered may vary depending on job-related knowledge, skills, and experience. In addition to equity, compensation packages include a wide range of medical, dental, vision benefits and ability to participate in our employee stock purchase plan. Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, breakfast and lunch for onsite employees, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match. Legal authorization to work in the United States is required.&nbsp;Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Head of Chemistry, Manufacturing & Controls

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.About the role&nbsp; Absci is seeking AI Research Interns to join its team of experts advancing generative and predictive modeling at the intersection of machine learning and drug discovery. As an AI Research Intern, you will develop AI models that generate and evaluate antibody therapeutic candidates. We are looking for exceptional contributors with backgrounds in deep learning, protein design and engineering, natural language processing, computer vision, and molecular dynamics to develop innovative approaches to creating and assessing therapeutic antibodies in silico.&nbsp; Absci’s computational teams (including its AI Scientists) develop and validate software platforms for antibody design and in silico assessment, while its Wet Lab teams experimentally validate its AI platforms, and its Drug Creation teams translate experimentally-validated AI designs into clinically-viable therapeutics.&nbsp; The ideal AI Research Intern candidate will: Use their expertise to influence the AI team's research agenda while maintaining high levels of responsibility and accountability for their work Demonstrate their curiosity about the problems we are attempting to solve by developing proficiency in disciplines that fall outside their own areas of expertise; Invest in ensuring their work is accessible and interpretable to scientists with other domain expertise Care as much about solving the technical problems related to designing antibody therapeutics as they do about translating solutions to the clinic Be available to work full-time for a 12 week duration Why Absci’s AI team? Absci offers AI Scientists a unique opportunity to not only develop novel, cutting edge machine learning models, but also apply these models in real-time to generate candidate antibody therapeutics. In particular: Absci provides its AI Scientists with access to industry-leading compute resources, enabling large-scale experimentation for model training and deployment.&nbsp; Absci maintains its own Wet Lab, enabling AI Scientists to validate novel modeling methods via both in silico and in vitro experimentation. Absci maintains and is growing its own internal pipeline of assets, enabling AI Scientists to see their work directly translated into therapeutic impact for patients. This position can be remote, hybrid, or on-site in New York City or Vancouver, WA.&nbsp; Key Responsibilities Support Absci’s AI Research team in developing state-of-the-art deep learning models for structure-based antibody design, antibody sequence design, antibody-antigen co-folding, antibody-antigen binding prediction, and physics-based antibody design and evaluation Analyze in silico and in vitro validation results to iteratively improve design and evaluation methodologies Deliver and publish high-impact research that advances Absci’s position as a thought leader in the field of AI antibody design Qualifications Pursuing a degree in Machine Learning, Computer Science, Computational Biology, Computational Chemistry, Biophysics, or a related field Research experience at the intersection of machine learning and protein design, molecular modeling, or a related field Fluency in Python and PyTorch Comfortable with design, implementation, and evaluation of state-of-the-art AI algorithms for protein design and protein structure prediction Demonstrated ability to work collaboratively in an ambitious, fast-paced, interdisciplinary environment Demonstrated experience presenting complex technical work to diverse audiences Absci’s AI team does not accept and is not responsible for fees related to unsolicited agency resumes. Compensation and Benefits The monthly salary range for this full-time position is $9,000 to $11,000. The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

AI Scientist Internship

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Administrative Partner Hybrid - Vancouver, Washington (3 days onsite per week) The Administrative Partner will work in a fast-paced, highly collaborative, and innovative drug discovery company. You will play a significant role in supporting members of our executive team in managing and directing the entire company.&nbsp; You will leverage your experience in supporting, organizing, and communicating with leaders to support communication throughout the organization and with Absci’s partners. This position requires strategic thinking and a high level of collaboration across multi-disciplinary teams within Absci.&nbsp; We work with a sense of urgency in a dynamic team and high-performance culture, striving to achieve the impossible!&nbsp; Responsibilities:&nbsp; Provides high-level administrative support and assistance to members of the&nbsp; Executive Team and general business administrative tasks as assigned&nbsp;&nbsp; Proactively manage and anticipate the day-to-day needs of the Executive to ensure they are prepared and organized for all internal and external meetings and events.&nbsp;&nbsp; Manage complex and fast-changing global calendars, using sound judgment to assess conflicting priorities and responsibilities.&nbsp; Performs clerical and administrative tasks, including drafting internal and external communications, memos, invoices, reports, and other documents for senior staff.&nbsp; Assists in the preparation of reports and other materials for the consideration of the Board of Directors.&nbsp; Handle highly confidential and/or sensitive matters and projects with discretion and tact.&nbsp; Arranges both international and domestic travel, meals, and accommodations for executives.&nbsp; Schedules and attends meetings on behalf of executives, taking notes, recording minutes, and providing direction.&nbsp; Receives incoming communication or memos on behalf of senior staff, reviews content, determines importance, and summarizes and/or distributes content to appropriate staff.&nbsp; Acts as gatekeeper and manager for the Executives’ schedules.&nbsp;&nbsp; Key role in the preparation of departmental meetings, agenda items, communications, and other functions.&nbsp; Assists with the preparation, monitoring, and improvement of workflows and other project management functions within the department.&nbsp; Prepare and process expense reports.&nbsp; Performs additional duties as assigned. Qualifications: Bachelor's degree in Business Administration or related field preferred.&nbsp;&nbsp; At least five (5) years of related experience working directly with senior management. Experience working in a position that requires confidentiality Expert skills in Excel, PowerPoint, and Word.&nbsp; Extensive knowledge of Google’s office platform, including email, Google Docs, Google Calendar, and other applications.&nbsp; Experience with scheduling for a global organization and managing multiple calendars, in various time zones&nbsp; Preferred (but not required): Education or work experience in a scientific field&nbsp; Previous experience with a high-growth, fast-paced startup organization.&nbsp;&nbsp; Ability to learn processes and procedures quickly and effectively.&nbsp; How We Thrive Together: Absci’s Core &nbsp;Values&nbsp; We are one team with one finish line: Collaborate across departments, proactively supporting leaders and colleagues to ensure everyone reaches shared goals and successes together. We embrace our differences: Foster an inclusive and welcoming environment by respecting diverse perspectives, preferences, and working styles. We deliver Results: Take ownership of your responsibilities, manage priorities efficiently, and ensure all logistics and tasks are completed with excellence and attention to detail. We do the right thing: Act with integrity and professionalism in every interaction, maintaining confidentiality, and communicating transparently. Innovate because lives depend on it: Continuously seek out tools, processes, or organizational improvements that make our teams more effective and amplify our impact. Believe in the impossible: Embracing creative solutions and supporting the team in achieving ambitious goals. The salary range for this position is $90,000-120,000/year. Competitive equity package applies. Pay offered may vary depending on job-related knowledge, skills, and experience. In addition to equity, compensation packages include a wide range of medical, dental, and vision benefits, and the ability to participate in our employee stock purchase plan. Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, breakfast and lunch for onsite employees, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match. Legal authorization to work in the United States is required. Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Administrative Partner

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Director, Protein Engineering and Structural Biology Vancouver, WA (onsite) The Director, Protein Engineering and Structural Biology, will lead a team of highly specialized scientists supporting Absci’s drug-creation programs at the intersection of antibody engineering, structural biology, and AI-enabled biologics discovery. This role contributes directly to advancing internal and partnered programs while embodying Absci’s values of Innovation, Collaboration, and Determination. We are considering candidates for both Associate Director and Director level positions: For Associate Director level: Demonstrated experience leading efforts related to protein engineering and/or structural biology in programs (such as project teams, technical initiatives, or technology development). Track record of scientific and technical contributions to pipeline advancement. For Director level: Broader experience providing strategic and scientific leadership across multiple protein engineering and/or structural biology projects or platforms. Proven ability to shape team vision, mentor staff, and influence cross-functional or organizational direction. Responsibilities Include:&nbsp; Scientific Leadership and Collaboration Lead a multidisciplinary team focused on antibody engineering, structural biology, and binding characterization to support multiple internal and external drug-creation programs. Mentor scientists and research associates, supporting technical development, scientific excellence, and career growth. Partner closely with the AI team to align experimental and computational strategies supporting Absci’s generative AI drug-creation platform, including collaboration on model evaluation and establishment of in-silico metrics to assess performance of de novo design and lead optimization efforts. Serve as the protein engineering lead on cross-functional project teams, partnering with computational biology, analytical development and translational teams to coordinate experiments and maintain alignment on timelines, resources and objectives. Regularly summarize and present data to internal and external stakeholders to support informed decision-making to advance programs. Maintain awareness of emerging technologies and the competitive landscape in biologics discovery. Research and Innovation: Lead efforts to develop and optimize platforms for mAb and multispecific therapeutics, from design to production, testing, and evaluation. Rationally design molecules, perform antigen/antibody structural analyses to recommend residue-level changes that improve interaction function, specificity, stability, and manufacturability. Design and implement binding and biophysical assays to assess the mutation impacts on protein structure and function. Coordinate closely with Absci teams to ensure high-quality protein expression, purification, and biophysical characterization of complex biologics and antigens. Partner with Translational biology teams to provide mechanistic insight into target biology and antibody–target interactions, supporting target assessment and MOA understanding. Profile for Success: PhD in life sciences with 8+ years of experience (including 5+ years in biopharma or biotech) or MS with equivalent experience. Proficiency in protein structure–function analysis and computational modeling (e.g., Schrödinger, MOE, Rosetta), with hands-on experience designing and optimizing bispecific and multispecific antibodies. Deep understanding of antibody structure-function relationships, sequence optimization, and expression/purification workflows. Experience in binding and interaction analyses (e.g., BLI, SPR) and/or biophysical characterization techniques (e.g., analytical SEC, DSF, DLS). Familiarity with Fc engineering, half-life extension strategies, antibody developability, and immunogenicity assessment. Experience in deploying AI/ML models for protein sequence and structure analysis to enable biologics design and optimization is a plus.&nbsp; Demonstrated success progressing one or more biologics programs to lead candidate stage. Experience managing teams of PhD-level scientists and research associates. Track record of peer-reviewed publications and/or patent filings. Excellent oral, written, and interpersonal communication skills.&nbsp; How We Thrive Together: Absci’s Core &nbsp;Values&nbsp; We Believe in the Impossible: We are one team with one finish line:&nbsp; We embrace our differences: We deliver Results:&nbsp; We do the right thing:&nbsp; Innovate because lives depend on it. Compensation and Benefits The salary range for this position is $165,000 - 230,000/year. The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match.&nbsp;Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Director, Protein Engineering and Structural Biology

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.About the role&nbsp; Absci is seeking AI Scientists to join its team of experts advancing generative and predictive modeling at the intersection of machine learning and drug discovery. As an AI Scientist, you will develop AI models that generate and evaluate antibody therapeutic candidates. We are looking for exceptional contributors with backgrounds in deep learning, protein design and engineering, natural language processing, computer vision, and molecular dynamics to develop innovative approaches to creating and assessing therapeutic antibodies in silico.&nbsp; Absci’s computational teams (including its AI Scientists) develop and validate software platforms for antibody design and in silico assessment, while its Wet Lab teams experimentally validate its AI platforms, and its Drug Creation teams translate experimentally-validated AI designs into clinically-viable therapeutics. The ideal AI Scientist candidate will: Care as much about solving the technical problems related to designing antibody therapeutics as they do about translating solutions to the clinic; Use their expertise to influence the AI team's research agenda while maintaining high levels of responsibility and accountability for their work; Demonstrate their curiosity about the problems we are attempting to solve by developing proficiency in disciplines that fall outside their own areas of expertise, constantly increasing the scale and impact of their contributions; Invest in ensuring their work is accessible and interpretable to scientists with other domain expertise. Why Absci’s AI team? Absci offers AI Scientists a unique opportunity to not only develop novel, cutting edge machine learning models, but also apply these models in real-time to generate candidate antibody therapeutics. In particular: Absci provides its AI Scientists with access to industry-leading compute resources, enabling large-scale experimentation for model training and deployment.&nbsp; Absci maintains its own Wet Lab, enabling AI Scientists to validate novel modeling methods via both in silico and in vitro experimentation. Absci maintains and is growing its own internal pipeline of assets, enabling AI Scientists to see their work directly translated into therapeutic impact for patients. This position can be remote, hybrid, or onsite in New York, NY or Vancouver, WA.&nbsp; Key Responsibilities Develop state-of-the-art deep learning models for structure-based antibody design, antibody sequence design, antibody-antigen co-folding, antibody-antigen binding prediction, and physics-based antibody design and evaluation Partner with teammates in AI Research, Platform Engineering, and Computational Biology to identify key challenges and design innovative, AI-driven solutions Analyze in silico and in vitro validation results to iteratively improve design and evaluation methodologies Deliver and publish high-impact research that advances Absci’s position as a thought leader in the field of AI antibody design Qualifications PhD or equivalent experience in Machine Learning, Computer Science, Computational Biology, Computational Chemistry, Biophysics, or a related field 3+ years of research experience at the intersection of machine learning and protein design, molecular modeling, or a related field, ideally including industry experience Fluency in Python and PyTorch Comfortable with design, implementation, and evaluation of state-of-the-art AI algorithms for protein design and protein structure prediction Expertise in large-scale model training Demonstrated ability to work collaboratively in an ambitious, fast-paced, interdisciplinary environment Demonstrated experience presenting complex technical work to diverse audiences Strong publication record in respected, high-impact journals and conferences Absci’s AI team does not accept and is not responsible for fees related to unsolicited agency resumes. Compensation and Benefits The base salary range for this position is $160,000- $260,000. The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.&nbsp; Absci offers highly competitive salaries and benefits including medical, dental, and vision insurance, unlimited vacation, parental leave, employee assistance programs, voluntary life and disability insurance, annual bonus potential, the ability to participate in our employee stock purchase plan, a 401(k) with a generous company match, and so much more.Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

AI Scientist

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.About the role Absci is seeking AI Scientists to join its team of experts advancing generative and predictive modeling at the intersection of machine learning and drug discovery. As an AI Scientist with a focus on Drug Creation, you will develop AI models that generate and evaluate antibody therapeutic candidates. We are looking for exceptional contributors with backgrounds in deep learning, protein design and engineering, natural language processing, computer vision, and molecular dynamics to develop innovative approaches to creating and assessing therapeutic antibodies in silico.&nbsp; Absci’s computational teams (including its AI Scientists) develop and validate software platforms for antibody design and in silico assessment, while its Wet Lab teams experimentally validate its AI platforms, and its Drug Creation teams translate experimentally-validated AI designs into clinically-viable therapeutics. The ideal AI Scientist candidate will: Care as much about solving the technical problems related to designing antibody therapeutics as they do about translating solutions to the clinic; Use their expertise to influence the AI team's research agenda while maintaining high levels of responsibility and accountability for their work; Demonstrate their curiosity about the problems we are attempting to solve by developing proficiency in disciplines that fall outside their own areas of expertise, constantly increasing the scale and impact of their contributions; Invest in ensuring their work is accessible and interpretable to scientists with other domain expertise. Why Absci’s AI team? Absci offers AI Scientists a unique opportunity to not only develop novel, cutting edge machine learning models, but also apply these models in real-time to generate candidate antibody therapeutics. In particular: Absci provides its AI Scientists with access to industry-leading compute resources, enabling large-scale experimentation for model training and deployment.&nbsp; Absci maintains its own Wet Lab, enabling AI Scientists to validate novel modeling methods via both in silico and in vitro experimentation. Absci maintains and is growing its own internal pipeline of assets, enabling AI Scientists to see their work directly translated into therapeutic impact for patients. This position can be remote, hybrid, or onsite in New York City or Vancouver, WA. Key Responsibilities Collaborate closely with cross-functional teams comprising disease biologists, Structural Biologists, Wet Lab scientists, and computational biologists to define antibody design criteria and deliver AI designs that meet drug creation program goals and target product profiles&nbsp; Adapt and deploy deep learning models for structure-based antibody design, antibody sequence design, antibody-antigen co-folding, antibody-antigen binding prediction, and physics-based antibody design and evaluation in real-world drug design campaigns Collaborate closely with Wet Lab scientists and Structural Biologists to design and deliver AI antibody libraries and associated Wet Lab workflows that enable in vitro assessment of model performance Analyze in silico and in vitro validation results to iteratively improve design and evaluation methodologies Communicate and present experimental results in a manner that is accessible to audiences with highly-diverse backgrounds, driving discussions that lead to high-quality, informed decision-making and program progression Deliver and publish high-impact research that advances Absci’s position at the forefront of Wet Lab-integrated AI antibody discovery Qualifications PhD or equivalent experience in Machine Learning, Computer Science, Computational Biology, Computational Chemistry, Biophysics, or a related field 3+ years of research experience at the intersection of machine learning and protein design, molecular modeling, or a related field, ideally including industry experience Demonstrated experience in developing and applying molecular simulation and/or computational biophysics tools Fluency in Python and familiarity with PyTorch Comfortable with design, implementation, and evaluation of state-of-the-art AI algorithms for protein design and protein structure prediction Expertise in large-scale model deployment Demonstrated ability to work collaboratively in an ambitious, fast-paced, interdisciplinary environment, including with Wet Lab scientists. Demonstrated excellence in cross-disciplinary communication and collaboration, and in presenting complex technical work to diverse audiences Strong publication record in respected, high-impact journals and conferences Basic understanding of the drug discovery process with an earnest desire to learn more Absci’s AI team does not accept and is not responsible for fees related to unsolicited agency resumes.&nbsp; Compensation and Benefits The base salary range for this position is $160,000- $260,000. The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.&nbsp; Absci offers highly competitive salaries and benefits including medical, dental, and vision insurance, unlimited vacation, parental leave, employee assistance programs, voluntary life and disability insurance, annual bonus potential, the ability to participate in our employee stock purchase plan, a 401(k) with a generous company match, and so much more.Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

AI Scientist, Drug Creation

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.We are currently seeking a skilled and highly experienced Legal Operations Manager to join our Legal team. You will play a significant role in supporting SEC, Nasdaq, securities, and corporate governance matters for the company and its subsidiaries. In addition, this position will assist the Legal department on commercial and strategic transactions on an as-needed basis. Opportunities to expand the practice area are encouraged. Willing to train as needed. You will leverage your background and understanding of corporate governance and securities matters to drive the business forward in its mission to deliver better drugs to patients. You will be focused on assisting the Legal team in providing business-minded solutions, comprehensive strategic and tactical advice, and the highest-quality legal services to support Absci’s delivery of next-generation biologics to patients. Responsibilities:&nbsp; Draft, execute, and manage the full lifecycle of contracts across functions and programs. Review, or assist in the review of, and negotiate a high volume of routine legal agreements, including but not limited to: Confidentiality Agreements (CDAs/NDAs) Consulting Agreements Work Orders and Scopes of Work (SOWs) Sponsored Research Agreements (SRAs) Master Services Agreements (MSAs) Material Transfer Agreements (MTAs) Support the legal, finance and scientific teams in executing agreements with CROs, academic collaborators, vendors, and consultants. Provide guidance to stakeholders on contractual rights and responsibilities. Assist with preparation and management of board and committee minutes, agendas, reporting calendars, written consents, routine legal resolutions, secretary certificates, powers of attorney, and other board documents. Support the preparation and filing of Form 8-Ks, 10-K, 10-Qs, Section 16 reporting, proxy statements and other SEC filing documents, including assisting the Disclosure Committee.&nbsp; Support the coordination and execution of board meetings, including preparation and distribution of materials through the electronic board distribution portal. Support onboarding of Directors and executive officers. Coordinate matters related to Annual Meeting of Stockholders, including D&amp;O questionnaires and ESG. Assist with M&amp;A, financings and other strategic transactions. Assist in the formation, dissolution and maintenance of corporate entities, including international subsidiaries. Review and assist in administering corporate governance policies. Maintain records and proactively design legal file management systems for corporate subsidiaries, director and officer information, corporate record keeping, transaction execution, governance policies, and compliance processes. Aid attorneys and participate in projects across the department, including employment law or other transactional matters. Qualifications: Legal Operations Manager Bachelor’s degree in finance, law, business administration, or a similar discipline; paralegal certificate required. Minimum 8 years’ of paralegal experience (with a focus on corporate governance, securities and/or public company reporting); some in-house experience preferred Experience preparing, managing and maintaining board minutes, agendas, stockholder meeting materials, and corporate recordkeeping Experience preparing and filing Section 16 reports (Forms 3, 4 and 5) preferred Ability to multi-task and work independently, partnering across all levels of the organization High attention to detail is essential, combined with a positive, partnership-oriented approach Advanced proficiency with MS Office (Word, Excel, PowerPoint) Pay Range: $115,000 - 147,000 Legal Operations Sr. Manager (In addition to Manager level Qualifications) Bachelor’s degree in finance, law, business administration, or a similar discipline; paralegal certificate required. Advanced degree (JD, MBA, or equivalent) preferred. Minimum 10 years’ of paralegal experience (with a focus on corporate governance, securities and/or public company reporting); some in-house experience preferred Proven experience taking initiative to anticipate organizational needs, flag potential issues, and drive collaboration among cross-functional partners to achieve successful outcomes. Ability to proactively evaluate and recommend new tools and technologies to optimize legal operations and reporting workflows. Pay Range $137,000 - $176,000 Preferred (but not required): Education or work experience in life sciences&nbsp; Previous experience with contract management systems like Conga or LinkSquares.&nbsp;&nbsp; Previous experience with patent and trademark administrative matters, including experience with&nbsp; US, PCT, and foreign prosecution, drafting formality documents, attending to document legalization, and complying with priority document requirements.&nbsp; How We Thrive Together: Absci’s Core &nbsp;Values&nbsp; We are one team with one finish line: Collaborate across departments, proactively supporting leaders and colleagues to ensure everyone reaches shared goals and successes together. We embrace our differences: Foster an inclusive and welcoming environment by respecting diverse perspectives, preferences, and working styles. We deliver Results: Take ownership of your responsibilities, manage priorities efficiently, and ensure all logistics and tasks are completed with excellence and attention to detail. We do the right thing: Act with integrity and professionalism in every interaction, maintaining confidentiality, and communicating transparently. Innovate because lives depend on it: Continuously seek out tools, processes, or organizational improvements that make our teams more effective and amplify our impact. Competitive equity package applies. Pay offered may vary depending on job-related knowledge, skills, and experience. In addition to equity, compensation packages include a wide range of medical, dental, vision benefits and ability to participate in our employee stock purchase plan. Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, breakfast and lunch for onsite employees, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match. Legal authorization to work in the United States is required.&nbsp;Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Legal Operations Manager

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Lead Clinical Trial Manager&nbsp; Vancouver, WA (Onsite), Remote/Hybrid (US-based) We are seeking a dynamic Clinical Research Operations Manager to lead our clinical research initiatives and manage the operational aspects of our clinical trials. This pivotal role combines the scientific expertise of clinical research with the organizational skills of operations management to ensure the efficient and effective execution of studies across various therapeutic areas meeting regulatory standards and company objectives. The ideal candidate will have a strong background in the life sciences, a deep understanding of clinical trial processes, and experience in regulatory affairs to oversee both the scientific and logistical elements of clinical research. Responsibilities:&nbsp; Develop and maintain effective working relationships with cross-functional teams, external partners (CROs, vendors), and study sites to ensure collaboration and alignment on trial objectives. Manage Contract Research Organizations (CROs) to ensure that all clinical operations are carried out in alignment with the study’s goals, budget, and timelines. Ensure robust patient recruitment and retention strategies are in place and effectively executed. Author, review, and maintain Standard Operating Procedures (SOPs) related to clinical research and operations ensuring high quality, compliance with the study protocol and regulatory requirements across all trials. Support design, implementation, and oversight of clinical trials from concept through completion, ensuring adherence to protocols, regulatory requirements, and ethical standards. Identify potential risks and implement contingency plans. Ensure accurate data collection, documentation, and record-keeping. Support analysis and interpretation of clinical data, prepare reports, and communicate findings to internal stakeholders and regulatory agencies. Stay informed about industry developments, regulatory changes, and advancements in clinical research methodologies to inform trial design and execution strategies. Responsible for the integrity, confidentiality, and security of all research data. Qualifications: Bachelors Degree in life sciences, pharmacology or related field a must&nbsp; Advanced degree (MSc., Ph.D., PharmD, MD) in life sciences, pharmacology, or related field preferred Minimum of 2-3 years of experience in phase 1 clinical research and operations within the pharmaceutical or biotechnology industry, with experience in immunology and/or dermatology studies being a plus. Good working knowledge of Good Clinical Practice (GCP), FDA regulations, ICH guidelines, and other regulatory requirements in clinical research. Familiarity with the IND and CTA filing process. Exceptional organizational, communication, and leadership skills, with the ability to manage multiple projects and teams in a fast-paced environment. Strong analytical and problem-solving abilities, with a meticulous attention to detail. Demonstrated capability to work collaboratively across various departments and with external partners to achieve objectives. Ability to work in a fast-paced environment and manage multiple projects simultaneously. Ability to travel up to 20% per month as needed to oversee clinical trials at investigator sites,&nbsp; onsite meetings with vendors, and conferences The salary range for this position is $145,000- $165,000/year. Competitive equity package applies. Pay offered may vary depending on job-related knowledge, skills, and experience. In addition to equity, compensation packages include a wide range of medical, dental, and vision benefits andthe&nbsp; ability to participate in our employee stock purchase plan. Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, breakfast and lunch for onsite employees, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match.Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Lead Clinical Trial Manager

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Content Marketing &amp; Design Manager&nbsp; Remote&nbsp; Absci is seeking an experienced and hands-on Marketing and Communications professional to drive digital marketing and communications initiatives within our pioneering AI-driven drug discovery biotech. You will manage content creation, social media &amp; digital marketing, and help drive external communications initiatives.&nbsp; Responsibilities:&nbsp; Execute digital marketing campaigns across web, email, and social media, following established strategic guidance (LinkedIn, X, YouTube). Operate and maintain company social media channels, including developing content, posting updates, and engaging with followers in alignment with company messaging Draft, edit, and publish original content (social posts, blogs, email newsletters, web copy) that translates complex scientific information into engaging, audience-appropriate material Monitor online channels for brand mentions and engagement opportunities; respond to comments and inquiries as the company’s digital voice Stay informed on current trends in biotech communications and digital marketing best practices, incorporating actionable ideas Collect and report on performance analytics for digital campaigns, suggesting operational improvements where possible. Maintain and update website content as directed, ensuring technical accuracy and a positive user experience. Coordinate basic graphic design, layout, or video needs for digital platforms. Collaborate with internal subject matter experts and external partners to source content and ensure technical accuracy. Serve as the day-to-day point for our PR agency and Supreme Optimization (web/ads) Manage freelance graphic designers and medical-science writing contractors, ensuring SLAs, budgets, and timelines are met Qualifications: 5+ years in Pharmaceutical or Biotech marketing at a clinical-stage biotech or pharma, and a Bachelor's degree. A combination of education and experience will be considered.&nbsp; Proven experience managing brand social media, websites, and email communications with demonstrable engagement growth in life sciences contexts Strong graphic design and marketing technology proficiency (including Adobe Creative Suite, Canva,&nbsp; Hootsuite, WordPress, and Google Analytics) with a demonstrated portfolio of infographics, presentations, and digital assets Exceptional writing and storytelling skills; portfolio of press materials, decks, blog posts, or thought-leadership content Strong project management skills; ability to juggle concurrent campaigns and tight deadlines Self-starter who works independently and escalates strategically when needed The salary range for this position is $110,000- $ 150,000 per year.&nbsp; Preferred: Hands-on experience supporting or organizing participation in conferences, trade shows, or industry events Basic design, video editing, or website skills Familiarity with search marketing or paid advertising Previous agency experience&nbsp; How We Thrive Together: Absci’s Core &nbsp;Values&nbsp; We Believe in the Impossible: Approach every marketing challenge with creativity, resourcefulness, and crafting digital experiences that champion groundbreaking science. We are one team with one finish line: Collaborate closely with scientists, leadership, and other team members, ensuring every marketing initiative supports our shared goals and celebrates collective success. We embrace our differences: welcome diverse perspectives from both inside and outside the organization when developing content or campaigns, ensuring our messaging is inclusive and resonates with biotech’s global community. We deliver Results: Take ownership of your projects from concept to completion, execute with excellence, and measure performance to ensure our digital marketing achieves tangible impact. We do the right thing: Communicate our science transparently and ethically, uphold integrity in all digital interactions, and act as a responsible steward of the company’s values. Innovate because lives depend on it: Seek out and implement creative digital tools and approaches that amplify our mission. When applying, please include your portfolio and a brief explanation of your experience in the biotechnology or pharmaceutical industry.&nbsp; Competitive equity package applies. Pay offered may vary depending on job-related knowledge, skills, and experience. In addition to equity, compensation packages include a wide range of medical, dental, vision benefits and ability to participate in our employee stock purchase plan. Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, breakfast and lunch for onsite employees, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match. Legal authorization to work in the United States is required. Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Content Marketing and Design Manager

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Senior Research Associate, Pharmacology &amp; Bioassays Location: Vancouver, WA (Onsite) Position: Full-Time, Senior Research Associate (Sr. RA) We are seeking a highly motivated and skilled Senior Research Associate (Sr. RA) to join our Pharmacology &amp; Bioassays team. The successful candidate will play a key role in advancing preclinical drug discovery by executing cell-based assays and cell line engineering for various therapeutic programs.&nbsp; This position involves hands-on benchwork and requires experience with primary cell culture, disease-relevant mechanistic assays, mechanisms of action (MoA) assays, and reporter cell-based assays. The role will focus on drug discovery, supporting mechanistic studies, and generating data to guide the progression of Absci’s biologics pipeline. Key Responsibilities: Maintain and culture primary cell types, and run various in-vitro/ex-vivo assays contributing to the development of pharmacology work-packages. Contribute to design, development and hands-on execution of in-vitro and ex-vivo disease-relevant assays for MOA studies and therapeutic testing. Troubleshoot and refine assays, ensuring reproducibility and robustness in both medium- and high-throughput formats. Perform data analysis, interpret and present experimental data at various platforms. Collaborate with interdisciplinary teams, including cellular screening to integrate data from cell-based assays and support drug discovery goals. Contribute to the preparation of SOPs, study protocols, and data presentations for regulatory and internal purposes. Ensure adherence to best practices in assay development, data management, and experimental execution. Required Qualifications: BSc in Biology, Cell Biology, Immunology, Biotechnology, or related field with 5+ years of industry experience in cell-based assays and primary cell culture work, OR MSc with 3+ years of relevant industry experience. Hands-on experience in primary cell culture, including immune cells (PBMCs, T-cells, NK cells), cancer cell lines, and other disease-relevant models. Experience in mechanistic assays, such as MoA assays, ligand-binding assays, ADCC, CDC, ADCP, and cellular uptake assays. Experience in reporter cell-based assays, with the ability to develop and implement these assays. Experience with flow cytometry, ELISA, Western blot, qPCR, and multiplexing technologies. Proficiency in data analysis software such as GraphPad Prism, SoftMax Pro to interpret and visualize experimental results. Ability to troubleshoot assays, ensuring high-quality and reproducible data. Excellent communication skills, with the ability to present data effectively to a variety of stakeholders and contribute to decision-making. Strong organizational skills, with the ability to prioritize tasks and manage multiple projects simultaneously. Demonstrated success working in a matrixed, highly collaborative team environment, contributing to both individual and team goals. How We Thrive Together: Absci’s Core &nbsp;Values&nbsp; We Believe in the Impossible We are one team with one finish line We embrace our differences We deliver Results We do the right thing Innovate because lives depend on it. Compensation and Benefits The salary range for this position is $88,000 - 100,000/year. The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match. Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Senior Research Associate

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Absci is seeking an experienced Network Engineer for a 6-month, full-time contract based at our Corporate Headquarters in Vancouver, WA. This highly impactful role will be integral to the assessment, resolution, and improvement of diverse network challenges within our dynamic environment. The ideal candidate is a self-motivated professional with deep technical expertise who excels both independently and as part of a team. Responsibilities: Design, install, configure, and support enterprise network systems, including routers, switches, and firewalls Monitor network performance and proactively identify and resolve issues to ensure minimal downtime Work closely with IT Operations and Help Desk team members to deliver on network-related projects and issue resolution Maintain up-to-date network documentation, including diagrams and configurations. Knowledge of enterprise server and storage solutions, including VMWare Experience with AWS networking/server/storage environments Qualifications:&nbsp; 6 years of related experience, a mixture of education and experience will be considered. Proven expertise in designing, implementing, and supporting enterprise-grade networks. Advanced proficiency in managing Palo Alto Firewalls (highly desired). Practical knowledge of VMware platforms and AWS network/server/storage architectures. Strong troubleshooting skills and a collaborative mindset with the ability to work independently in a fast-paced environment. How We Thrive Together: Absci’s Core &nbsp;Values&nbsp; We Believe in the Impossible: You find new solutions for complex problems and don’t settle for “good enough.” We Are One Team with One Finish Line: You collaborate and communicate clearly with IT, Help Desk, and project teams for seamless network operations. We Embrace Our Differences: You value diverse perspectives to strengthen network design and troubleshooting. We Deliver Results: You consistently resolve issues and deliver network projects on time, supporting our fast-paced environment. We Do the Right Thing: You maintain the highest standards for security and reliability in every decision. Innovate Because Lives Depend on It: You bring fresh ideas to enhance systems, knowing that quality infrastructure supports real-world impact. Compensation and Benefits The salary range for this position is $110,000 -130,000/year. The range provided is a reasonable estimate of the base salary for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. This position will be employed through a staffing agency and will receive benefits through the staffing agency, including Medical insurance, Vision insurance, Dental insurance, and 401(k)Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Network Engineer

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Sr. Scientist, Immunology &amp; Bioassays Vancouver, WA (onsite) We are seeking a highly motivated, collaborative, and innovative scientist to join our Pharmacology and Bioassays team. The qualified candidate will have deep expertise in immunology and strong experience developing and executing in vitro and ex vivo cell-based assays to interrogate immune mechanisms and immune-mediated disease mechanisms.&nbsp; This individual will be responsible for helping to establish and expand our preclinical assays, will actively contribute from the bench, delivering in vitro and ex vivo work packages to support and advance Absci’s drug development pipeline. The successful candidate will demonstrate clear and professional communication, effectively collaborate with colleagues across a highly matrixed environment, and be capable of presenting scientific results to project teams.&nbsp; Responsibilities Design, develop, and execute preclinical in vitro and ex vivo cell-based assays to advance therapeutic programs and support target validation, MOA elucidation, and lead characterization. Analyze and interpret complex experimental datasets to define functional activity, mechanistic insight, and biological relevance of therapeutic candidates. Identify, evaluate, and implement new assay models, technologies, and experimental approaches to strengthen disease-relevant biology and assay capabilities. Serve as an immunology subject matter expert, integrating literature, experimental data, and disease biology to support project decisions and milestone advancement. Independently troubleshoot and optimize complex assays, applying scientific judgment to resolve technical and biological challenges. Contribute to the development and expansion of advanced in vitro and ex vivo research capabilities within the Pharmacology &amp; Bioassays team. Author and review SOPs, study reports, and scientific presentations to ensure clarity, rigor, and reproducibility. Required Qualifications Ph.D. or equivalent advanced degree in Pharmacology, Immunology/Inflammation, Physiology, cell biology, or related disciplines with at least 5+ years of post-PhD academic and/or industry experience in immunology, immune-mediated inflammatory diseases, or related field, establishing direct experimental experience with the complex biology of inflammatory diseases Extensive experience with flow-based in-depth characterization of immune cell populations in blood and tissue samples. Experience with cell-based assays, ELISA, MSD, qPCR, microscopy, histology/pathology (e.g. IF/IHC/ISH). Demonstrated expertise with complex 2D/3D functional cell-based and tissue-based assays to investigate disease biology and PK/PD relationship.&nbsp; &nbsp;Experience with leveraging complex data sets to characterize and establish a drug’s therapeutic mechanisms of action Ability to be hands-on and work in the lab, write protocols, and execute studies leveraging Absci’s in-house capabilities&nbsp; Experience working with project/research teams with functional responsibility to propose strategy, analyze, interpret, and present complex data to inform decisions &nbsp;Ability to collaborate in writing protocols and reports Outstanding communication skills with demonstrated ability to make effective presentations in a broad range of settings Preferred Skills and Experience Demonstrated record of leveraging in vitro/ex-vivo pharmacology models to explore antibody-based drug discovery.&nbsp; Experience with therapeutics programs leading to drug candidate nomination in one or more of the following therapeutic areas: oncology, immunology/inflammation, metabolic diseases Experience authoring study protocols, reports, and/or regulatory documents, including IBs, IND filings, and/or NDAs Experience working with complex patient-derived cell-based 2D/3D culture systems or ex vivo tissue models Ability to independently generate, analyze, and interpret multi-omics data sets Strong statistical analysis skills and an ability to articulate findings and make recommendations from complex study results Experience mentoring scientists, leading cross-functional project teams, and a track record of successful management of external teams Experience working with vendors and CROs to execute studies, analyze data, and generate reports promptly Compensation and Benefits The salary range for this position is $130,000 - 145,000/year. The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match.Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Senior Scientist, Immunology & Bioassays

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Associate Director, Pharmacology &amp; Bioassays Location: Onsite, Vancouver, WA (HQ) About the role: Absci is seeking a visionary scientific leader to join us as Associate Director, Pharmacology &amp; Bioassays. In this pivotal role, you will spearhead a multidisciplinary team driving in vitro and ex vivo functional characterization of next-generation biologics, including antibodies, bispecifics, and engineered binding proteins, to advance Absci’s discovery and preclinical pipeline. Associate Director, Pharmacology &amp; Bioassays will serve as the group’s primary subject matter expert (SME) in pharmacology, mechanistic biology, and functional assay strategy. They will ensure that data generated by the team is rigorous, reproducible, and directly informs program strategy from early discovery through IND-enabling studies. This is a critical scientific leadership role reporting to the Head of Disease Biology and partners closely with Disease Biology, Protein Engineering, and High-Throughput Screening (HTS) functions at Absci. Key Responsibilities Scientific &amp; Functional Leadership: Lead, mentor, and develop a high-performing team focused on in vitro and ex vivo assay development, mechanistic biology, and functional pharmacology. Serve as the primary pharmacology SME on internal project teams. Provide scientific direction on assay strategies and mechanistic understanding of biologic therapeutics, including MOA, receptor pharmacology, signaling pathways, and functional readouts. Uphold strong scientific rigor, reproducibility, data quality, and interpretation standards across all team deliverables. Pharmacology &amp; Mechanistic Biology Oversee the design, development, optimization, and execution of cell-based functional assays that evaluate potency, mechanistic activity, selectivity, and biological relevance of Absci’s therapeutic candidates. Guide assay strategies supporting: Target validation and MOA elucidation Lead identification and optimization Structure–function and functional epitope analysis Cell biology studies relevant to disease-associated pathways Integrate functional biology insights into quantitative pharmacology frameworks (e.g., dose–response modeling, receptor occupancy, PK/PD translation). Program Strategy &amp; Cross-Functional Partnership Represent the Pharmacology &amp; Bioassays group on cross-functional project teams, translating complex data into actionable recommendations and clear articulation of program risks. Collaborate closely with Protein Engineering, HTS, and Disease Biology to drive cohesive, milestone-aligned experimental plans. Identify data gaps, propose scientifically sound solutions, and guide planning to ensure programs remain on track with the right assays and decision-making metrics. Support in vivo study design by developing complementary in vitro/ex vivo assays to inform MOA, PD biomarkers, and dose selection. Operational Excellence Build and maintain state-of-the-art workflows and technologies relevant for cell-based and ex vivo assay systems (e.g., primary cell systems, cytokine/receptor signaling assays, flow cytometry, high-content imaging). Implement best practices for assay robustness, statistical rigor, documentation, and reproducibility. Manage team resources, timelines, and workload across multiple programs in a dynamic, fast-paced environment. Evaluate and oversee external collaborations, including CROs and academic groups, as needed. Qualifications Education &amp; Experience PhD in Pharmacology, Cell Biology, Biochemistry, Immunology, or a related discipline with 5-7+ years of industry experience, or an equivalent combination of advanced degree and experience. Demonstrated track record of scientific leadership and team development. Proven experience supporting or leading antibody drug development programs. Scientific Expertise Deep expertise in pharmacology and mechanistic biology of biologics, including antibodies, bispecifics, and other engineered protein therapeutics. Strong background in cell biology, including primary cell systems, cytokine biology, receptor–ligand interactions, signaling pathways, and effector function mechanisms. Extensive experience developing, executing, and troubleshooting in vitro/ex vivo functional assays, such as: Primary immune-cell or primary-cell functional assays 3D/complex multi-component cell-based assay systems Signaling pathway and reporter-based assays Cytokine/chemokine readouts (ELISA/MSD) Flow cytometry and high-content imaging ADCC/CDC or other immune-effector assays (when relevant) Demonstrated experience advancing biologic drug candidates through key stages of drug development, including target validation, lead optimization, and IND-enabling studies, with direct contribution to at least one successful IND submission. Leadership &amp; Interpersonal Skills Proven ability to lead and inspire scientific teams while maintaining high standards of quality and rigor. Excellent communication skills with the ability to translate complex biological data into program-relevant insights. Highly collaborative, strategic, proactive, and adaptable to evolving priorities. Ability to thrive in a dynamic biotech environment and influence across functions. How We Thrive Together: Absci’s Core &nbsp;Values&nbsp; We Believe in the Impossible We are one team with one finish line We embrace our differences We deliver Results We do the right thing Innovate because lives depend on it. Compensation and Benefits The salary range for this position is $160,000 -190,000/year. The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match. Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Associate Director, Pharmacology & Bioassays

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Senior R&amp;D Project Manager Vancouver, WA (onsite) Ready to drive execution on high-impact programs? We are seeking an enthusiastic and highly experienced Program Manager to join our Program &amp; Portfolio Management team. You will leverage your background and understanding of stakeholder management and leadership in order to drive execution on our highly cross-functional pipeline programs and play a significant role in the success of our overall portfolio strategy. This position requires strategic thinking and a high level of collaboration across multiple levels of the organization, from individual contributors to executive leadership and across multi-disciplinary teams within Absci, including AI Research, Protein Engineering, High Throughput Screening, Disease Biology, and Purification &amp; Analytics.&nbsp; A sense of urgency and drive is essential to thrive in our dynamic, high-performance culture. With your passion for driving initiatives and proven ability to work autonomously, you will be highly successful in the following areas: Responsibilities:&nbsp; Support corporate and portfolio strategy by safeguarding the success of highly cross-functional Drug Creation pipeline programs and communicating effectively with leadership about risks, costs, and opportunities.&nbsp; Facilitate cross-functional strategy discussion to align objectives, scope and pressure-test plans, surface and mitigate risk, drive decision making to deliver milestones on or ahead of schedule, and escalate issues with clearly presented solutions that link directly to the key program objectives. Define the program team's structure and culture to build high-performing cross-functional teams.&nbsp; Facilitate and document program team meetings, cross-functional communication, and decision making, and ensure alignment with technical groups and leadership Drive execution of cross-functional programs by planning, tracking, and holding stakeholders accountable for program tasks and deadlines. Use project management software to forecast and track program costs and time to ensure milestones are achieved on time and within budget.&nbsp; Identify, assess, prioritize &amp; manage project-related risks, bottlenecks, and interdependencies to ensure milestones are achieved on time and within budget. Work with stakeholders and scientific leadership to challenge assumptions, understand failure modes, and implement corrective actions while working to build a system where operational activities are increasingly automatic and seamless. .&nbsp; Simultaneously balance activities between multiple projects of various scopes. Contribute to the development and refinement of company-wide best practices for program management Qualifications: Program Manager Bachelor’s degree in a science-related field with 5+ years of experience in a biotech-related field or equivalent technical work experience; or a Master’s degree and 3+ years; or a PhD Degree and 1+ years. Proven experience with Change Management and Conflict Resolution with a proactive mindset Demonstrated ability to operate in a fast-paced, matrixed team environment&nbsp; Strong verbal and written communication skills, with the ability to clearly articulate project goals, strategies, and results to stakeholders at all levels across the organization Working knowledge of project management software (MS Project, SmartSheet, etc.) Familiar with workflows involving protein engineering, cloning, high-throughput screening, protein purification, and/or analytical chemistry Demonstrated commitment to Absci's core values. The salary range for this position is $106,000 - 130,000/year. Senior Program Manager Bachelor’s degree in a science-related field with 8+ years of experience in a biotech-related field or equivalent technical work experience; or a Master’s degree with 6+ years; or a PhD with 3+ years. Proven track record of successfully managing complex, cross-functional programs in drug discovery or related fields. Proven experience with Change Management and Conflict Resolution with a proactive mindset Excellent organizational and leadership skills with experience building and managing high-performing cross-functional teams in a matrixed environment Excellent verbal and written communication skills, with ability to clearly articulate project goals, strategies, and results to stakeholders at all levels across the organization Ability to think with a portfolio-level mentality, ensuring that individual program decisions align with the overall company goals Working knowledge of project management software (MS Project, SmartSheet, etc.) Familiar with complex workflows involving protein engineering, cloning, high-throughput screening, protein purification, and/or analytical chemistry Willingness to mentor and support junior program managers and to foster a culture of accountability, innovation, and continuous improvement. Demonstrated commitment to Absci's core values. The salary range for this position is $127,000 - $150,000/year. Preferred (but not required): Project management training In-depth or hands-on experience with SmartSheet or other project management software&nbsp; In-depth experience with early stage discovery and drug development for biologics Familiarity with late stage drug development including pre-clinical, CMC, and regulatory considerations for biologics The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match. Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Senior R&D Program Manager

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Clinical Research Operations Director&nbsp; Vancouver, WA (Onsite), Remote/Hybrid (US-based) We are seeking a dynamic Clinical Research Operations Director to lead our clinical research initiatives and manage the global operational aspects of our clinical trials. This pivotal role combines the scientific expertise of clinical research with the organizational skills of operations management to ensure the efficient and effective execution of studies across different therapeutic and geographic areas that meet regulatory standards and company objectives. The ideal candidate will have a strong background in the life sciences, a deep understanding of clinical trial processes, as well as regulatory affairs to oversee both the scientific and logistical elements of clinical research. Responsibilities:&nbsp; Trial Oversight and Execution: Support design, implementation, and oversight of clinical trials from concept through completion, ensuring adherence to protocols, regulatory requirements, and ethical standards. Manage Contract Research Organizations (CROs) to ensure that all clinical operations are carried out in alignment with the study’s goals, budget, and timelines. Oversee junior staff assigned to a project, but remain responsible for the success of a clinical project or program. Operational Management &amp; Compliance: Author, review, and maintain Standard Operating Procedures (SOPs) related to clinical research and operations ensuring high quality, compliance with the study protocol and regulatory requirements across all trials. Ensure robust patient recruitment and retention strategies are in place and effectively executed. Drive Program level consistency in data collection and compliance Drive analysis, troubleshooting, and interpretation of clinical data, prepare reports, and communicate findings to internal stakeholders and regulatory agencies. Ensure accurate data collection, documentation, and record-keeping. Responsible for the integrity, confidentiality, and security of all research data. Risk Management &amp; Strategy: Identify potential risks and implement contingency plans. Keep abreast of industry developments, regulatory changes, and advancements in clinical research methodologies to inform trial design and execution strategies. Collaboration &amp; Communication: Develop and maintain effective working relationships with cross-functional teams, external partners (CROs, vendors), and study sites to ensure collaboration and alignment on trial objectives. You Will Be Successful If You: Effectively build rapport and confidence when presenting trial updates, data, and regulatory information to Clinical Research Investigators and their staff. Are an exceptional leader who can successfully coordinate multiple complex clinical projects simultaneously across cross-functional teams to meet aggressive timelines. Proactively use your strong analytical and problem-solving abilities to troubleshoot operational issues and interpret clinical data to drive decision-making and project success. Demonstrate meticulous attention to detail in all operational and compliance documentation. Are adept at collaborating across various departments and with external partners to achieve shared objectives. Can manage global projects effectively, navigating multiple time zones and cultural differences in a fast-paced, agile environment. Qualifications: Bachelor’s Degree in life sciences, pharmacology, or a related field. A minimum of 8 years of direct experience in the operational management of multi-phase (I-IV) clinical research within the pharmaceutical or biotechnology (including CRO) industry. Demonstrated working knowledge of all relevant regulations, including Good Clinical Practice (GCP), FDA regulations, and ICH guidelines. Documented experience with or direct involvement in the IND (Investigational New Drug) and CTA (Clinical Trial Application) filing processes. Willingness and ability to travel up to 20% per month to oversee clinical trials at investigator sites, attend onsite meetings with vendors, and participate in conferences. Preferred: Experience in immunology, women’s health, and/or dermatology studies. Advanced degree (MSc., Ph.D., PharmD, MD) in life sciences, pharmacology, or a related field. The salary range for this position is $180,000 - $215,000. Competitive equity package applies. Pay offered may vary depending on job-related knowledge, skills, and experience. In addition to equity, compensation packages include a wide range of medical, dental, and vision benefits and ability to participate in our employee stock purchase plan. Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, breakfast and lunch for onsite employees, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match. Legal authorization to work in the United States is required.&nbsp;Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Director, Clinical Operations

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.We are currently seeking a dedicated and strategically minded Clinical Scientist Senior Director to join our Clinical Development team at Absci. In this pivotal role, you will help translate Absci’s AI-powered drug design into successful drug development programs. This position is ideal for a Senior Director who brings substantive experience in both clinical development and medical affairs. Absci is bringing potentially revolutionary medicines to fulfill unmet patient needs with a dedicated group of experienced team members who embrace working in multiple functions.&nbsp; In this important position role, your accountability spans a range of clinical science deliverables for the development program(s) at large as well as individual clinical trials.&nbsp; Given Absci’s paradigm-creating approach to drug development, contributing to medical affairs strategy and&nbsp; execution are important components of the position.&nbsp; You will leverage your deep background in clinical trial design/execution, medical data oversight, and scientific communication and KOL engagement to ensure our development programs generate high-quality, decision-ready data while building the scientific foundation needed to support our pipeline as it advances toward commercialization. The successful candidate will readily incorporate AI tools&nbsp; and technology into daily practice to efficiently achieve mission objectives. Responsibilities: Able to function independently with respect to key deliverables with close internal and external stakeholder collaboration. Develop expertise in assigned therapeutic areas to serve as a clinical and scientific subject-matter expert for assigned therapeutic area and indication, providing hands-on oversight of protocol execution and clinical data quality to enable decision ready outcomes. Engage clinical investigators and study sites to ensure timely and&nbsp; quality study execution. Participating in Investigator meeting planning and execution and assist with site initiation as needed. Be a leading voice in ideation of study designs, protocols, charters, publication plans, publication concepts and associated deliverables to fulfill Absci’s clinical development and medical affairs objectives . Support investigators, site staff, CROs/ CRAs on study protocol and related questions. Work closely with medical monitors on proactive data review, systematically identifying trends, safety signals, and data quality issues in collaboration with clinical operations under an established data monitoring plan. Collaborate with a cross-functional team to drive protocol development and governance approval, authoring and reviewing study design, endpoints, eligibility criteria, and related documents; ensure integrity of protocols throughout the trial lifecycle. Partner cross-functionally to translate clinical strategy into study concept documents, protocols, and related regulatory facing materials, ensuring alignment with Absci’s development objectives and Good Clinical Practice (GCP) standards. Proven ability to build and maintain strong relationships and contribute to interactions with external key opinion leaders to optimize clinical programs (e.g. advisory boards, individual engagements, steering committees, etc.). Experience in (or clear ability) with investigator engagement to optimize clinical trial conduct. Includes presenting at investigator meetings. Maintain excellent management and leadership skills, often without direct authority, including informing and motivating internal/external stakeholders, setting and monitoring goals and action plans. Build, track and manage relationships with specific external stakeholders, including key opinion leaders, disease advocacy groups, patient support groups, and educational foundations. Build and maintain company awareness of scientific, clinical and competitive landscape, periodically conducting informative reviews for internal stakeholders including senior leadership by reviewing and synthesizing data&nbsp; to support program strategy. Contribute to medical affairs activities, including support for scientific communication platforms, external expert engagement, KOL strategy, scientific conference strategy, publication planning and strategy of near market or marketed assets and bridging clinical development and medical affairs to ensure continuity across the product lifecycle. Contribute to regulatory submissions and health authority interactions. Present scientific findings internally and externally, including at leadership forums and scientific conferences; serve as a contributing author on peer-reviewed publications and data presentations. Provide guidance on the identification and management of CROs, collaborators, and consultants to support key clinical and medical affairs deliverables. Qualifications: A PhD or PharmD is required.&nbsp; 10+ years of pharmaceutical or biotechnology clinical drug development experience, with a demonstrated track record in late-phase (Phase 2/3) trial execution, scientific data review, and data quality oversight. Proven ability to bridge clinical development and medical affairs functions, including experience with developing and managing KOLs and publication strategy for clinical development programs,&nbsp; scientific communications, and medical support for marketed or near-market products. Experience contributing to regulatory submissions, health authority interactions, and/or authoring clinical regulatory documents in compliance with ICH, FDA, and EMA guidelines. Strong written and oral communication skills with the ability to clearly convey complex clinical and scientific data to internal leadership committees and external stakeholders. Preferred (but not required): Track record in successfully translating AI-driven drug discovery and/or targets into clinical development programs. Ability and experience successfully incorporating AI tools into daily work, efficiently achieving clinical development and medical affairs objectives. Industry and/or academic experience in Dermatology or Women’s Health therapeutic areas, including designing, monitoring, and interpreting clinical trials in these indications. &nbsp;How We Thrive Together: Absci’s Core&nbsp;Values &nbsp; We believe in the impossible &nbsp; We are one team with one finish line &nbsp; We embrace our differences &nbsp; We deliver results &nbsp; We do the right thing &nbsp; We innovate because lives depend on it Compensation and Benefits The salary range for this position is $262,000 - $315,000 per year.&nbsp;The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match. Legal authorization to work in the U.S. is required.&nbsp; AbSci may agree to sponsor an individual for an employment visa now or in the future if there is a shortage of individuals with particular skills for this job.&nbsp;&nbsp; In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire.&nbsp;&nbsp; This position is for our Vancouver, WA location&nbsp;(just outside of Portland, OR) - AbSci may agree to offer relocation assistance for this role.&nbsp;Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Clinical Development Scientist

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.As Director, Purification &amp; Analytical Development, you are a strategic leader who guides Absci’s work in biologics. You will lead and mentor teams working on purification and analytical support, and set the strategy for scientific and operational success. You help your teams manage uncertainty, focus on broad goals, and deliver solutions that impact patients. Your leadership will be instrumental in: Establishing and implementing strategic objectives for Purification and Analytical Development, in partnership with Absci’s executive team. Leading operational units, aligning them with the organizational vision and cascading a clear functional strategy. Steering our efforts on the frontlines of innovation—empowering the team to pursue what others call impossible. Responsibilities:&nbsp; Protein Purification and Analytical Development Oversee the design and execution of purification processes for soluble and membrane-bound proteins. Oversee analytical method development for characterization of therapeutic proteins using a variety of techniques (e.g., ELISA, BLI, HPLC, and MS). Lead troubleshooting and adoption of new technologies for purification and analytical support. Train and empower scientists in hands-on operation and maintenance of critical instrumentation. Integrate purification and analytical strategies to support drug discovery, selection of lead or drug candidates, antibody characterization, and tech transfers. Developability Assessment Design, implement, and oversee assessment of therapeutic protein developability. Develop and integrate computational, biophysical, and experimental workflows to assess and mitigate risks such as stability, immunogenicity, and expression challenges. Documentation &amp; Compliance Ensure accurate, comprehensive documentation (SOPs, technical reports, method validations) that meets quality standards. Review and interpret results from standard analytical techniques to assess protein purity, impurities, and process clearance. Champion use of electronic lab notebooks (ELN), LIMS, UNICORN, Benchling, SoftMax Pro, JMP, and related platforms for data integrity and process tracking. Support tech transfer and contribute to regulatory submission packages as needed. Stakeholder Influence &amp; Communication: Represent Purification &amp; Analytical Development with senior management, executives, and external partners—inspiring trust, negotiating on key matters, and balancing stakeholder priorities. Advocate for your teams, communicate cross-functionally, and unify diverse perspectives toward essential company goals. Qualifications:&nbsp; PhD with 10+ years, or MS with 12+ years of progressive industry experience in drug discovery &amp; analytical science, or related field—with demonstrated success leading teams and organizations through scale, complexity, and ambiguity. Demonstrated mastery of purification, analytical development and developability assessment, with a track record on influencing functional and organizational strategy. Deep familiarity with the competitive landscape and where Absci’s approach can break the mold. How We Thrive Together: Absci’s Core &nbsp;Values&nbsp; We Believe in the Impossible We are one team with one finish line We embrace our differences We deliver Results We do the right thing Innovate because lives depend on it. Compensation and Benefits The salary range for this position is $190,000 - 230,000/year. The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match. Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Director, Process Development and Analytical Development

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Head of People Operations Remote, Hybrid, or Onsite Vancouver, WA The Head of People Operations reports to the SVP, People &amp; Experience and leads the strategy and execution of scalable, compliant, and AI-enabled people operations. This role toggles between strategic vision and hands-on execution, directly building, optimizing, and operating core people systems and processes. The role owns the full people infrastructure including HR systems and automation, employee lifecycle operations, analytics, talent management, and global workforce operations to drive efficiency, consistency, and a high quality employee experience while intentionally embedding and reinforcing the company’s core values across all programs, processes, and employee interactions. Responsibilities People Systems, AI &amp; Analytics Own, optimize and manage the HR technology ecosystem (HRIS, payroll, benefits, performance, compensation, equity), ensuring strong data integrity, system integration, and user experience. Design and implement automation and AI-enabled workflows across People operations to improve efficiency, reduce manual work, and support scalable processes. Build and maintain workforce analytics, including dashboards and reporting, translating talent data into actionable insights and ensuring data accuracy. Negotiate with vendors on platform capabilities, contract terms, and feature enhancements to support strategic priorities. Employee Lifecycle &amp; Programs Oversee day-to-day employee lifecycle operations, ensuring accurate processing, strong data quality, and a consistent employee experience. Develop and maintain standard operating procedures (SOPs) to support consistency, scalability, and audit readiness. Lead the design and continuous improvement of core People programs (performance management, compensation, engagement, and organizational changes), ensuring they are analytically grounded, manager-friendly, and consistently executed. Compliance &amp; Policy Proactively manage employment compliance, including monitoring regulatory changes, completing required filings, and maintaining mandated postings. Conduct audits and implement corrective actions to ensure ongoing compliance and reduce risk. Develop, administer, and track policies and required training programs, ensuring completion and documentation. Talent &amp; Performance Own the end-to-end performance management architecture from goal setting through annual reviews and calibration with a focus on creating high-performing, accountable teams. Lead talent management programs (talent reviews, succession planning, development planning) to support leadership pipeline and internal mobility. Partner with leaders to assess organizational health and identify and address talent risks. Drive internal mobility infrastructure and leadership capability programs to support career development and succession. Global Operations Manage international workforce operations, including coordination with EOR partners. Oversee People operations vendors, including day-to-day management, contract support, and performance monitoring. You Will Be Successful If You: Deep expertise in HRIS platforms, payroll systems, benefits administration, and HR technology architecture; hands-on configuration, workflow automation, and a proven track record of leading systems implementations, process redesign, and digital modernization efforts required Proven track record managing people operations across a complex, multi-state and/or international workforce. Strong analytical and data storytelling skills; comfortable building executive ready narratives from complex workforce data. Solid HR fundamentals: employee relations, employment law, HR and benefit compliance, performance management, and policy development. Experience designing and executing talent management programs: performance cycles, succession planning, talent reviews, and high-potential development. Demonstrated fluency with AI tools and automation in HR workflows and able to articulate specific examples of how AI was applied to improve HR outcomes. Experience designing learning and development programs, including automated training delivery, onboarding acceleration, and skill-building initiatives. Systems thinker who can simultaneously drive operational rigor and strategic vision. Exceptional cross-functional influencer who builds trusted relationships with Finance, Legal, IT, and business leaders, as well as external vendors and stakeholders. Resilient, solutions-oriented change leader with experience guiding organizations through structural changes, systems transitions, and cultural evolution in fast-paced, evolving environments Qualifications:&nbsp; 10+ years of progressive HR/People Operations experience 3 years in a senior or lead role spanning multiple HR disciplines. Bachelor's degree required; advanced degree in HR, Business Administration, or related field preferred. How We Thrive Together: Absci’s Core &nbsp;Values&nbsp; We Believe in the Impossible: We are one team with one finish line:&nbsp; We embrace our differences: We deliver Results:&nbsp; We do the right thing:&nbsp; Innovate because lives depend on it. Compensation and Benefits The salary range for this position is $175,000 - 200,000/year. The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match. Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Head of People Operations

About Absci Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets. Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com or follow us on LinkedIn (@absci), X (@Abscibio), and YouTube.Human Resources Generalist Hybrid, Vancouver, WA Contract 5-6 Months About the role: We are currently seeking a detail-oriented HR Generalist to join our Human Resources team on a contract basis. This role will be responsible for benefits and compensation administration and compliance, leave management, and HR program support across the entire company. You work with a sense of urgency and thrive in a dynamic team and high-performance culture. This role is the first point of contact for HR-related matters which requires solid collaboration skills, excellent communication, and the ability to handle sensitive information with discretion while maintaining data accuracy and confidentiality&nbsp; Responsibilities:&nbsp; Support core HR programs and processes, ensuring a positive employee experience, strong stakeholder coordination, and accurate, timely system updates. Administer employee benefits programs (e.g., health, 401(k), FSA, wellness), including enrollments, changes, terminations, and open enrollment activities. Conduct compensation analysis using market data; develop insights, support pay recommendations, and contribute to merit and compensation planning cycles. Maintain accurate, confidential employee records and HRIS data in compliance with applicable laws and company standards. Serve as a primary employee resource, responding to inquiries on policies, benefits, and HR programs in a timely, compliant, and customer-focused manner. Manage employee lifecycle transactions (hires, changes, terminations) in partnership with Payroll, IT, and other stakeholders. Administer leave of absence programs (FMLA, ADA, state and company leaves), including case management, documentation, and communication. Ensure compliance with federal, state, and local regulations (e.g., wage &amp; hour, ADA, FMLA, EEO) and maintain required reporting and documentation. Support diversity, equity, and inclusion initiatives, compliance tracking, and reporting (e.g., EEO, affirmative action). Contribute to the development and continuous improvement of HR programs, processes, and employee engagement initiatives. Promote a positive, inclusive work environment and employee well-being. Qualifications:&nbsp; 5 years of related HR experience with a Bachelor’s degree; or 3 years and a Master’s degree Deep knowledge of federal, state, and local employment laws and regulations Strong analytical and data interpretation skills with proficiency Proficiency with Microsoft Office Suite, HRIS, and ATS systems (Rippling, Ashby are preferred) Demonstrated ability to maintain strict confidentiality and handle sensitive information Experience with benefits administration and leave management processes How We Thrive Together: Absci’s Core &nbsp;Values&nbsp; We Believe in the Impossible: We are one team with one finish line:&nbsp; We embrace our differences: We deliver Results:&nbsp; We do the right thing:&nbsp; Innovate because lives depend on it. Compensation and Benefits The salary range for this position is $95,000 - $115,000/year. The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law Absci offers highly competitive salaries and benefits, including medical, dental, vision insurance, unlimited vacation, parental leave, employee assistance program, voluntary life and disability insurance, annual bonus potential, and 401(k) with a generous company match. Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact hiring@absci.com.&nbsp;

Head of IT

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